Protein Alignment Nlg1 and Ces2f

DIOPT Version :10

• Sequence 1: NP_731172.2
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_001073334.2
• Gene: Ces2f / 71903
• MGIID: 1919153
• Length: 561
• Species: Mus musculus
• Alignment Length: 616
• Identity: 184/616 - (29%)
• Similarity: 293/616 - (47%)
• Gaps: 102/616 - (16%)

  Fly   131 SSEHEPSTTHHPERRHVVPDKLQYTQEIQVKQGRLMGITRRFQVTSGLRQVDQFLGLPYAEAPTG 195
            |||..|....|             |.::   :|:.:.:|   .:.:|   ...|||:|:|:.|.|
Mouse    29 SSEASPIRNTH-------------TGQV---RGKFVHLT---DIKAG---AHNFLGIPFAKPPVG 71

  Fly   196 NRRFMPPGAPLPWQGLKIARHLPPVCPQKLPDLSPHGSENMSRARHKHLSRLLPYLRTESEDCLY 260
            ..||.||.||.||.|::.....|.:|.|....::..|.        |.:..:||.. :.||||||
Mouse    72 PLRFAPPEAPEPWSGVRDGTSQPAMCLQNDDIVNLEGL--------KIIKMILPPF-SMSEDCLY 127

  Fly   261 LNLYVP-H-EEPQSTPKQYAVLVYLHGESFEWNSGNPYDGSVLSSYGEVIVVTVNYRLGVLGFLR 323
            ||:|.| | :|..:.|    |:|:|||........:.||||||::..:|:||...||||:.||..
Mouse   128 LNIYTPAHAQEGSNLP----VMVWLHGGGLVAGMASMYDGSVLAATEDVVVVVTQYRLGIPGFYS 188

  Fly   324 PSIDAHNIANYALLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASGLFHRA 388
            .. |.....|:..|||.|||||:::||..|||:...|||.|.|.|...|::.::|||:.||||||
Mouse   189 TG-DEQARGNWGFLDQTAALHWVQQNIANFGGNPDSVTLFGQSAGGTSVSFHVLSPVSQGLFHRA 252

  Fly   389 ILMSGSAMSDWAASNQSLQLTMQIAHALECPLNEHVEAEDDDVLLDCLRHRRYQDILHIPTALTQ 453
            |:.||.|:......:....:..::|:...|      |..:.:.|:.|||.:...:||    |:::
Mouse   253 IMESGVALLPTIIPDSPEMIFTKVANLSGC------ETSNSEALVRCLRGKSEAEIL----AMSK 307

  Fly   454 FSTSLGPIVDGHVIPNQPYKVMGHYTEHFSRYDLLFGITESESYHTLAAL-ALEEGLRENERDNL 517
            ....:..:|||..:|..|.|::.  :..|.....:.|:...|....:..: ...:.:|:..|:|
Mouse   308 AFRFMPAVVDGKFLPRHPKKLLA--SADFHPVPSIIGVNNDEYGWIIPKIFKFSQTIRKINRNN- 369

  Fly   518 LRFYMQSRFD--IRP----DLALAATLKKYQDMYNNPIKATNLEHRDVVLDILSDARVVGPLLQT 576
            |:..|:...:  :.|    ||.:...|:..:|.:     ...::.|:::.|.|    ::.|.||.
Mouse   370 LKAIMKITTEQMMLPSECGDLLIEEYLRDTEDPW-----TLQMQFREMIGDFL----IIIPALQV 425

  Fly   577 GMF---HADVNRRNYMYVFGHNSATGPFAHLPH--SIMGEELAFIFGAPLAAAGPFPSG---NYT 633
            ..|   ||.|    |.|.|.|.|:...:....|  :..|:||..|||:       |..|   ::|
Mouse   426 ARFQRSHAPV----YFYEFQHRSSLLKYFRPWHVKADHGDELYLIFGS-------FFWGLKFSFT 479

  Fly   634 VQEKLLSEAVMAYWTNFVKTGNPKAPWKGIFINSHALEWDRYDLDWPEFNRRAQAYLNIGIPPTV 698
            .:|||||..:|.||.||.:.|||         ||..|.:      ||..| :...||.:.|.|:|
Mouse   480 AEEKLLSRKMMKYWANFARYGNP---------NSEDLPY------WPASN-QDDLYLQLDIHPSV 528

  Fly   699 GYKYRQIYMNFWNKELPDELNQIAAIQEQLQ 729
            |:..:...:.||.|.||.::.::....::::
Mouse   529 GHALKARRLPFWTKTLPQKMLELKGNHDKIK 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_731172.2	COesterase	157..710	CDD:395084	173/569 (30%)
Ces2f	NP_001073334.2	COesterase	32..540	CDD:395084	176/592 (30%)