Protein Alignment Nlg1 and Ces1a

DIOPT Version :9

• Sequence 1: NP_001246966.1
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_001177304.1
• Gene: Ces1a / 679817
• RGDID: 1583671
• Length: 563
• Species: Rattus norvegicus
• Alignment Length: 617
• Identity: 174/617 - (28%)
• Similarity: 278/617 - (45%)
• Gaps: 99/617 - (16%)

  Fly   141 HPERRHVVPDKLQYTQEIQVKQGRLMGITRRFQVTSGLRQ-VDQFLGLPYAEAPTGNRRFMPPGA 204
            ||....|| |.|         ||:::|   ::....|..| |..|||:|:|:.|.|:.||.||..
  Rat    19 HPSSPPVV-DTL---------QGKVLG---KYISLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQP 70

  Fly   205 PLPWQGLKIARHLPPVCPQ------KLPDLSPHGSENMSRARHKHLSRLLPYLRTESEDCLYLNL 263
            ...|..:|.|...||:|.|      .|.::..:..||:.          |.|    ||||||||:
  Rat    71 AESWSFVKNATSYPPMCSQITGVGPVLSEVFTNQLENVP----------LEY----SEDCLYLNI 121

  Fly   264 YVPHEEPQSTPKQYAVLVYLHGESFEWNSGNPYDGSVLSSYGEVIVVTVNYRLGVLGFLRPSIDA 328
            |.|.:  .::..:..|:|::||........:.:||..||::.:|:||.:.||||:.|||... |.
  Rat   122 YSPTD--LTSKDRLPVMVWVHGGGLLSGGASTFDGLALSTHEKVVVVVIQYRLGIWGFLSTG-DE 183

  Fly   329 HNIANYALLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASGLFHRAILMSG 393
            |:..|:...||:|||.|::.||..||||.:.|||.|.|.|...|:.|::||:...||||||..||
  Rat   184 HSRGNWGHFDQVAALQWVQNNIVNFGGDPNSVTLFGESAGGESVSVLVLSPLTKNLFHRAISESG 248

  Fly   394 SAMSDWAASNQSLQLTMQIAHALECPLNEHVEAEDDDVLLDCLRHRRYQDILHIPTALTQFSTS- 457
            .|::.......:.....|:|.|..|......:      ::.|||.:..:::|.....:..|:..
  Rat   249 VALTPCLFRENTRLAAEQVAIATGCAATTSAD------IVRCLREKTEEELLATTLKMKFFALDL 307

  Fly   458 ----------LGPIVDGHVIPNQPYKVMGHYTEHFSRYDLLFGITESE---SYHTLAALALEEGL 509
                      |..::||.::|..|.:::..  ::|:....:.||.:.|   ...|:....|.|..
  Rat   308 HGDPRESYPFLTTVIDGVLLPKAPEEILSE--KNFNTVPYIVGINKQEFGWFIPTMMGYPLSESK 370

  Fly   510 RENERDNLLRFYMQSRFDIRPDLALAATLKKYQDMYNNPIKATNLEHRDVVLDILSDARVVGPLL 574
            .:.:....|.:......:|..:|...|| :||....:.|.|     .:|:.||::.|.....|.:
  Rat   371 LDQKTATSLLWKSYPLTNISKELTPVAT-EKYLGGSDCPDK-----KKDLFLDMMGDVLFAVPSV 429

  Fly   575 QTGMFHADVNRRNYMYVFG-HNSATGPFAHLPHSIM---GEELAFIFGAPLAAAGPFPSGNYTVQ 635
            ....:|.|.....|:|.|. |.|......  |.:::   |:|:..::|.|....|.      :.:
  Rat   430 IVARYHRDARATTYVYEFKYHPSFVSDMR--PKTVIADHGDEVYSVWGTPFLKEGA------SEE 486

  Fly   636 EKLLSEAVMAYWTNFVKTGNPKAPWKGIFINSHALEWDRYDLDWPEFNRRAQAYLNIG--IPPTV 698
            |..||..:|.:|.||.:.|||         |...|.      .|||::.: ::||.||  |....
  Rat   487 EINLSTMMMKFWGNFARNGNP---------NGEGLP------HWPEYDEK-ESYLQIGTTIQQAQ 535

  Fly   699 GYKYRQIYMNFWNKELPDELNQIAAIQEQLQK 730
            ..||:::  .||......|:.:  |.:|..||
  Rat   536 KLKYKEV--AFWTGLRGMEVEE--ATEEDTQK 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_001246966.1	COesterase	153..710	CDD:278561	161/583 (28%)
		Aes	<263..>408	CDD:223730	54/144 (38%)
Ces1a	NP_001177304.1	COesterase	24..545	CDD:278561	165/590 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810