Protein Alignment Nlg1 and Bche

DIOPT Version :10

• Sequence 1: NP_731172.2
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_075231.1
• Gene: Bche / 65036
• RGDID: 619996
• Length: 597
• Species: Rattus norvegicus
• Alignment Length: 602
• Identity: 176/602 - (29%)
• Similarity: 267/602 - (44%)
• Gaps: 83/602 - (13%)

  Fly   154 YTQE---IQVKQGRLMGITRRFQVTSGLRQVDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIAR 215
            :|:|   |..|.||:.|::  ..:..|  .|..|||:|||:.|.|:.||..|.....|..:..|.
  Rat    22 HTEEDVIITTKTGRVRGLS--MPILGG--TVTAFLGIPYAQPPLGSLRFKKPQPLNKWPDVYNAT 82

  Fly   216 HLPPVCPQKLPDLSP--HGSE------NMSRARHKHLSRLLPYLRTESEDCLYLNLYVPHEEPQS 272
            .....|.|.:....|  .|||      |:                  ||||||||:::|..:
  Rat    83 KYANSCYQNIDQAFPGFQGSEMWNPNTNL------------------SEDCLYLNVWIPVPK--- 126

  Fly   273 TPKQYAVLVYLHGESFEWNSGN--PYDGSVLSSYGEVIVVTVNYRLGVLGFLRPSIDAHNIANYA 335
             ||...|:|:::|..|:..:.:  .|||..|:....||||::|||:|.||||....::....|..
  Rat   127 -PKNATVMVWVYGGGFQTGTSSLPVYDGKFLTRVERVIVVSMNYRVGALGFLAFPGNSEAPGNMG 190

  Fly   336 LLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASGLFHRAILMSGSAMSDWA 400
            |.||..||.||:.||.||||:...|||.|.|.|||.|:..::.|.:..||.||||.|||:.:.||
  Rat   191 LFDQQLALQWIQRNIAAFGGNPKSVTLFGESAGAASVSLHLLCPQSYPLFTRAILESGSSNAPWA 255

  Fly   401 ASN--QSLQLTMQIAHALECPLNEHVEAEDDDVLLDCLRHRRYQDI-----LHIPTALTQFSTSL 458
            ..:  ::...|:.:|..:.|      ..|::..::.|||.:..|:|     |.:|:...: |.:.
  Rat   256 VKHPEEARNRTLTLAKFIGC------SKENEKEIITCLRSKDPQEILLNEKLVLPSDSIR-SINF 313

  Fly   459 GPIVDGHVIPNQPYKVMGHYTEHFSRYDLLFGITESESYHTLAALALEEGLRENERDNLLRFYMQ 523
            ||.|||..:.:.|:.::  .........:|.|:.:.|....|...|  .|..::....:.|...|
  Rat   314 GPTVDGDFLTDMPHTLL--QLGKVKTAQILVGVNKDEGTAFLVYGA--PGFSKDNDSLITRREFQ 374

  Fly   524 SRFDIR----PDLALAATLKKYQDMYNNPIKATNLEHRDVVLDILSDARVVGPLLQTGMFHADVN 584
            ...::.    ..|...|.|..|.|...:   .|...:|:...||:.|..::.|.|:.....|::.
  Rat   375 EGLNMYFPGVSSLGKEAILFYYVDWLGD---QTPEVYREAFDDIIGDYNIICPALEFTKKFAELE 436

  Fly   585 RRNYMYVFGHNSATGPFAHLPHSIMGEELAFIFGAPLAAAGPFPSGNYTVQEKLLSEAVMAYWTN 649
            ...:.|.|.|.|:..|:......:.|.|:.|:||.||..     ..|||..|::.|.::|..|.|
  Rat   437 INAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLER-----RVNYTRAEEIFSRSIMKTWAN 496

  Fly   650 FVKTGNPKAPWKGIFINSHALEWDRYDLDWPEFNRRAQAYLNIGIPPT-VGYKYRQIYMNFWNKE 713
            |.|.|:|    .|...||..         ||.|....|.||.:....: :..|.|.....||...
  Rat   497 FAKYGHP----NGTQGNSTV---------WPVFTSTEQKYLTLNTEKSKINSKLRAPQCQFWRLF 548

  Fly   714 LPDELNQIAAIQEQLQK 730
            .|..|.....|.|:.|:
  Rat   549 FPKVLEITGDIDEREQE 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_731172.2	COesterase	157..710	CDD:395084	168/577 (29%)
Bche	NP_075231.1	COesterase	25..545	CDD:395084	168/577 (29%)
		AChE_tetra	560..594	CDD:430146	2/6 (33%)