Protein Alignment Nlg1 and nlgn3b

DIOPT Version :10

• Sequence 1: NP_731172.2
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: XP_005165239.1
• Gene: nlgn3b / 567415
• ZFINID: ZDB-GENE-060526-197
• Length: 846
• Species: Danio rerio
• Alignment Length: 872
• Identity: 259/872 - (29%)
• Similarity: 393/872 - (45%)
• Gaps: 168/872 - (19%)

  Fly   148 VPDKLQYTQEIQVKQGRLMGITRRFQVTSGLRQVDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLK 212
            |...|.|...:....|||.|: |....|.||..|||:||:|||..|.|.:|||||.||..|.|::
Zfish    38 VASTLTYQPTVNTALGRLRGM-RVAVATEGLGPVDQYLGVPYAAPPVGEKRFMPPDAPSAWSGVR 101

  Fly   213 IARHLPPVCPQ----KLPDLSPHGSENMSRARHKHLSRLLPYLRTESEDCLYLNLYVPHE----- 268
            .|...||||||    .:||:.      |......::..:..||:.:||||||:|:|||.:
Zfish   102 NATRFPPVCPQTVRNAVPDIM------MPVWATYNMDTVATYLQEQSEDCLYMNIYVPTQSGTKR 160

  Fly   269 -----------------EPQSTPKQYAVLVYLHGESFEWNSGNPYDGSVLSSYGEVIVVTVNYRL 316
                             :.:..|:  .|::::||.|:...:||..|||||:|||.|||:|:|||:
Zfish   161 TGDMSADTERTEDDGLRDSRDDPR--PVMLFIHGGSYMEGTGNIMDGSVLASYGNVIVITLNYRV 223

  Fly   317 GVLGFLRPSIDAHNIANYALLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVA 381
            |:||||.....|.. .||.|||||.||.||.:||..||||..|||:.|...||:||:.|.:|..:
Zfish   224 GILGFLSTGDQAAK-GNYGLLDQIQALRWINKNIGYFGGDPGRVTVFGSGIGASCVSLLTLSHHS 287

  Fly   382 SGLFHRAILMSGSAMSDWAASNQSLQLTMQIAHALECPLNEHVEAEDDDVLLDCLRHRRYQDILH 446
            .|||||||:.||||:|.|:.:.|.::.|..:|..:.|.:   ::.:|   |:.|::.|.|::::.
Zfish   288 EGLFHRAIIQSGSALSSWSVNYQPVKYTRLLAERVGCNV---LDTQD---LVLCMQKRSYRELVE 346

  Fly   447 IPTALTQFSTSLGPIVDGHVIPNQPYKVMGHYTEHFSRYDLLFGITESESYHTLAALALEE--GL 509
            ......:|..:.||::||.:||:.|..:|..  ..|..||::.|:.:.|.:..:..:...|  |:
Zfish   347 QEIQPARFHVAFGPVIDGDLIPDDPEVLMEQ--GEFLNYDIMLGVNQGEGFRFVEGVVEPEEGGV 409

  Fly   510 RENERDNLLRFYMQSRFDIRPD--LALAATLKKYQDMYNNPIKATNLE-HRDVVLDILSDARVVG 571
            ..::.|..:..::.|.:.. |:  ..|..|:|   .||.:.....|.| .|..::.:.:|.:.|.
Zfish   410 SGSDFDFTVSDFVDSLYGY-PEGKDTLRETIK---FMYTDWADRDNPETRRKTLVAMFTDHQWVE 470

  Fly   572 PLLQTGMFHADVNRRNYMYVFGHNSAT---GPFAHLPHSIMGEELAFIFGAPLAAAGP---FPSG 630
            |.:.|...||......:.|.|.|:..:   .|:|...|   |:||.::||.||  .||   ||.
Zfish   471 PAVVTADLHARYGSPTFFYAFYHHCQSPMKPPWADSAH---GDELPYVFGVPL--IGPTELFPC- 529

  Fly   631 NYTVQEKLLSEAVMAYWTNFVKTGNPK--APWKGIFINSHALEWDRYDLDWPEFNRRAQAYLNIG 693
            |::..:.:||..||.|||||.|||:|.  .|....||::.|..::  ::.|.::....|.||:||
Zfish   530 NFSRNDIMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFE--EVTWAKYGPHDQLYLHIG 592

  Fly   694 IPPTVGYKYRQIYMNFWNKELPDELNQIAAIQEQLQKPGQEVITGHMSKYGPRDHGAEDPVRTLK 758
            :.|.|...||...:.||...:|                       |:.......|......|...
Zfish   593 LKPRVRDHYRATKVAFWKHLVP-----------------------HLYNLHDMFHYTSTTTRVPP 634

  Fly   759 LLLQEPS-LAGPTQSGESTETAAENMYNAPPTFGHVHKMQGGSDFEDLVTSTNSLESGEDHPQAP 822
            ||....| .|.|...|....|:.:.                                       |
Zfish   635 LLTTHSSHSATPRPGGNKARTSGKQ---------------------------------------P 660

  Fly   823 PETVAKS-----------EATMQLLIALITIIIVLNLLIYGTFLLRQ-RRRRAKALPFPAPK--- 872
            |::.|:|           ...:.:.||:...::.||:|.:.....|: :|.|....|.|||:
Zfish   661 PQSTARSGPLVIANPRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKRSRQDTPPQPAPQRQT 725

  Fly   873 ----LGGTILSYDGANDEELKRCSKSRDGDDSFVLEMTRKSNTYEAIKTGQRSLSCSTVDTHTKV 933
                |.....|..|.|.|||..|..         |.:|..|:..:...|.:||.....:.|.:.|
Zfish   726 PPIDLNYAPTSISGGNQEELSLCDP---------LRLTPASSPRDYALTLRRSPDDIPLMTPSSV 781

  Fly   934 CEWMSSQEAPKSGSF--NTATPPPQPI 958
            .      ..|.||:.  ||.|..|..:
Zfish   782 A------MTPNSGTMTPNTVTLTPNSV 802

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_731172.2	COesterase	157..710	CDD:395084	204/591 (35%)
nlgn3b	XP_005165239.1	COesterase	45..609	CDD:395084	204/593 (34%)
		Herpes_BLLF1	<753..>843	CDD:282904	14/56 (25%)