Protein Alignment Nlg1 and cel.2

DIOPT Version :9

• Sequence 1: NP_001246966.1
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_001020344.2
• Gene: cel.2 / 565117
• ZFINID: ZDB-GENE-061110-10
• Length: 551
• Species: Danio rerio
• Alignment Length: 553
• Identity: 161/553 - (29%)
• Similarity: 248/553 - (44%)
• Gaps: 115/553 - (20%)

  Fly   178 LRQVDQFLGLPYAEAPTGNRRFMPPGAPLP-WQGLKIARHLPPVCPQKLPDLSPHGSENMSRARH 241
            ||.:|.|.|:|:| ||.|  |...| .|.| |:|:..|......|.|
Zfish    43 LRYMDVFKGIPFA-APPG--RLQKP-VPHPGWEGVLKATEYSKRCIQ------------------ 85

  Fly   242 KHLSRLLPYLRTE---SEDCLYLNLYVPHEEPQSTPKQYAVLVYLHGESFEWNSGNP-------- 295
                  |..|:|:   ||||||||::||  :.::......|:|:::|..|....|..
Zfish    86 ------LNLLQTDTMGSEDCLYLNIWVP--QGKTVSYNLPVMVFIYGGGFLLGGGQGANFLDNYL 142

  Fly   296 YDGSVLSSYGEVIVVTVNYRLGVLGFLRPSIDAHNIANYALLDQIAALHWIKENIEAFGGDNSRV 360
            |||..::..|.|||||.|||:|.:|||... ||....||.|.||.||:.|:..||:||||:...:
Zfish   143 YDGEEIADRGNVIVVTFNYRVGSMGFLSTG-DADAPGNYGLWDQHAAISWVHRNIKAFGGNPDNI 206

  Fly   361 TLMGHSTGAACVNYLMVSPVASGLFHRAILMSGSAMSDWAASNQSLQLTMQIAHALECPLNEHVE 425
            |:.|.|.|:..||:.::||...||..|||..||.|:..||.:....:...:||..:.||
Zfish   207 TIFGESAGSTSVNFQIISPKNKGLIRRAISQSGVALCPWAINRNPRKFAEEIAKKVGCP------ 265

  Fly   426 AEDDDVLLDCLRHRRYQDILHIPTALT-----QFSTS----------LGPIVDGHVIPNQPYKVM 475
              .|..::.|||...       |.|:|     :.:||          |.|::||..||::|..:.
Zfish   266 --TDSGMVACLRRTD-------PKAVTLAGKVRLATSATEPIVHNLYLSPVIDGDFIPDEPDTLF 321

  Fly   476 GHYTEHFSRYDLLFGITESESYHTLAAL---ALEEGLRENERDNLLRFYMQSRFDIRPDLALAAT 537
            |:..:    .|.:.|:.:.:. |..|.|   ::...|.....:.:.........|...|..: ||
Zfish   322 GNAAD----IDYIAGVNDMDG-HIFATLDIPSINNALATTTEEEVQALATALSKDRGQDAGI-AT 380

  Fly   538 LKKYQDMYNNPIKATNLEHRDVVLDILSDARVVGPLLQTGMF-HAD--VNRRNYMYVFGHNSATG 599
            .::|...:.:  |....:.:..|:::.:|...:.| .||.:: |:|  .:.|.|.|:|..:|...
Zfish   381 FQEYTVNWGS--KPNKEDIKKTVVEMETDYIFLVP-TQTALYLHSDNAKSARTYSYLFSESSRIP 442

  Fly   600 PFAHLPHSIMGEELAFIFGAPLAAAGPFPSGNYTVQEKLLSEAVMAYWTNFVKTGNP-----KAP 659
            .|.....:...:||.::||.|...    |.| |..:.:.:|:.::||||||.:||||     |.|
Zfish   443 IFPLWMGADHADELQYVFGKPFTT----PLG-YFPRHRDVSKYMIAYWTNFAQTGNPNTGESKVP 502

  Fly   660 WKGIFINSHALEWDRYDLDWPEFNRRAQAYLNI 692
                             :.||||:.....||:|
Zfish   503 -----------------VTWPEFSNPGHQYLDI 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_001246966.1	COesterase	153..710	CDD:278561	161/553 (29%)
		Aes	<263..>408	CDD:223730	57/152 (38%)
cel.2	NP_001020344.2	COesterase	26..539	CDD:306613	161/553 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43903
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.910