Protein Alignment Nlg1 and ces3

DIOPT Version :10

• Sequence 1: NP_731172.2
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_001038401.1
• Gene: ces3 / 560651
• ZFINID: ZDB-GENE-030131-9563
• Length: 549
• Species: Danio rerio
• Alignment Length: 548
• Identity: 174/548 - (31%)
• Similarity: 262/548 - (47%)
• Gaps: 64/548 - (11%)

  Fly   181 VDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLPPVCPQKLPDLSPHGSENMSRARHKHLS 245
            |:|:||:|:|:.|.|..|...|.....|:|::.|.....:|.|. |::.|..:::|:..
Zfish    50 VEQYLGIPFAQPPVGPHRLAAPQPVQGWEGIRNATEYSSMCLQD-PNIVPKYAKSMTLE------ 107

  Fly   246 RLLPYLRTESEDCLYLNLYVPHEEPQSTPKQYAVLVYLHGESFEWNSGNPYDGSVLSSYGEVIVV 310
              ||.... ||||||||:|.|.:..:|  .::.|:|::||.:........|||:.|::|.:|:||
Zfish   108 --LPPTGV-SEDCLYLNVYTPSQRSES--DKFPVMVWIHGGALVIGGACMYDGTPLAAYEKVVVV 167

  Fly   311 TVNYRLGVLGFLRPSIDAHNIANYALLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACVNYL 375
            .:.||||:||:|... |.|...|:..|||||||.|:::||||||||...||:.|.|.|....:.|
Zfish   168 VIQYRLGILGYLSTG-DQHAQGNWGFLDQIAALQWVQQNIEAFGGDPQSVTIAGESAGGISASLL 231

  Fly   376 MVSPVASGLFHRAILMSGSAMSDWAASNQSLQLTMQIAHALECPLNEHVEAEDDDVLLDCLRHRR 440
            .:||:..|||.|||..||.|.....:....|.....||:..||      :....:||:.|:|...
Zfish   232 TLSPMTKGLFQRAIFQSGVATVKGYSFKDPLTYAKVIANITEC------DFSSSEVLVKCIREMT 290

  Fly   441 YQDILHIPTALTQFSTSLGPIVDGHVIPNQPYKVMGHYTEHFSRYDLLFGITESESYHTLAALAL 505
            .:.|  |..|..::... |..|||..|..||.:::  .::.|.:..:|.|.|..|...||:...|
Zfish   291 EEQI--IKAAQKKYRLP-GATVDGEFIKAQPEEIL--KSKDFPKIPILVGTTNHEFGWTLSHAIL 350

  Fly   506 ----EEGL-RENERDNLLRFYMQSRFDIRPDLALAATLKKYQDMYNNPIKATNLEHRDVVLDILS 565
                .:|: .::.:..|..||.....:....:|         |.|....| |..|.||...::|.
Zfish   351 PKDWAKGMDAKSAKQTLDFFYNAGASEANGIIA---------DEYFKNAK-TPEEIRDAFTELLG 405

  Fly   566 DARVVGPLLQTGMFHADVNRRNYMYVFGH-----NSATGPFAHLPHSIMGEELAFIFGAPLAAAG 625
            |..:|.|.::...:|.|.....|||.|.|     |.....|....|   |:|:.|:|||......
Zfish   406 DIIMVIPSIKVASYHRDAGAPVYMYEFQHGPSIANKFRPSFVKADH---GDEIGFMFGACFWDGQ 467

  Fly   626 PFPSGNYTVQEKLLSEAVMAYWTNFVKTGNPKAPWKGIFINSHALEWDRYDLDWPEFNRRAQAYL 690
            ...:|..|.:|..|...||.||.|||:||:|         |...:.|..||        ::..||
Zfish   468 VKVTGTLTEEENQLCRTVMKYWANFVRTGSP---------NPAPVPWPVYD--------QSNKYL 515

  Fly   691 NIGIPPTVGYKYRQIYMNFWNKELPDEL 718
            |:|:..|.|...::..:.|:.:|||.:|
Zfish   516 NLGLQQTEGQGLKKDKLLFFTEELPKKL 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_731172.2	COesterase	157..710	CDD:395084	169/538 (31%)
ces3	NP_001038401.1	COesterase	25..535	CDD:395084	169/538 (31%)