Protein Alignment Nlg1 and Ace

DIOPT Version :9

• Sequence 1: NP_001246966.1
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_001163600.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Alignment Length: 659
• Identity: 165/659 - (25%)
• Similarity: 253/659 - (38%)
• Gaps: 155/659 - (23%)

  Fly   158 IQVKQGRLMGITRRFQVTSGLRQVDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLPPVCP 222
            :|...|.:.|.:    ||...|:|..:.|:|||:.|..:.||..|....||.|:..|..|...|.
  Fly    45 VQTSSGPVRGRS----VTVQGREVHVYTGIPYAKPPVEDLRFRKPVPAEPWHGVLDATRLSATCV 105

  Fly   223 QKLPDLSP--HGSENMSRARHKHLSRLLPYLRTESEDCLYLNLYVP------------------- 266
            |:..:..|  .|.|..:           |.... ||||||:|::.|
  Fly   106 QERYEYFPGFSGEEIWN-----------PNTNV-SEDCLYINVWAPAKARLRHGRGANGGEHPNG 158

  Fly   267 ----------HEEPQSTPKQYAVLVYLHGESFEWNSG--NPYDGSVLSSYGEVIVVTVNYRLGVL 319
                      :..||:|.....:|::::|..|...|.  :.|:..::::.|.|||.:..||:|..
  Fly   159 KQADTDHLIHNGNPQNTTNGLPILIWIYGGGFMTGSATLDIYNADIMAAVGNVIVASFQYRVGAF 223

  Fly   320 GFLR-----PSIDAHNI-ANYALLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACVNYLMVS 378
            |||.     ||..|... .|..|.||..|:.|:|:|..||||:...:||.|.|.|::.||..::|
  Fly   224 GFLHLAPEMPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGESAGSSSVNAQLMS 288

  Fly   379 PVASGLFHRAILMSGSAMSDWAASNQSLQLTMQIAHAL--ECPLNEHVEAEDDDVLLDCLRH--- 438
            ||..||..|.::.||:..:.|  |:.:.:..::|..||  :|..|..:...:...::.|:|.
  Fly   289 PVTRGLVKRGMMQSGTMNAPW--SHMTSEKAVEIGKALINDCNCNASMLKTNPAHVMSCMRSVDA 351

  Fly   439 --------RRYQDILHIPTALTQFSTSLGPIVDGHVIPNQPYKVMGHYTEHFSRYDLLFGITESE 495
                    ..|..||..|:|         |.:||..:|..|..:|  .|.....||:|.|
  Fly   352 KTISVQQWNSYSGILSFPSA---------PTIDGAFLPADPMTLM--KTADLKDYDILMG----- 400

  Fly   496 SYHTLAALALEEGLRENERDNLLRFYMQSRFD-IRPDLALAATLKKYQDMYNNPI-KATNLEHRD 558
                            |.||....|.:....| ...|.|.|....||.::.||.. |||..|...
  Fly   401 ----------------NVRDEGTYFLLYDFIDYFDKDDATALPRDKYLEIMNNIFGKATQAEREA 449

  Fly   559 VVLDILS------------DARVVG------PLLQTGMFHADVNRRNYMYVFGHNSATGPFAHLP 605
            ::....|            ..|.||      |..:.....|:.....:.|.|.|.::|..:....
  Fly   450 IIFQYTSWEGNPGYQNQQQIGRAVGDHFFTCPTNEYAQALAERGASVHYYYFTHRTSTSLWGEWM 514

  Fly   606 HSIMGEELAFIFGAPLAAAGPFPSGNYTVQEKLLSEAVMAYWTNFVKTGNPKAPWKGIFINSHAL 670
            ..:.|:|:.:.||.||.     .|..|...|:.|.:.:::....|.|||||....:
  Fly   515 GVLHGDEIEYFFGQPLN-----NSLQYRPVERELGKRMLSAVIEFAKTGNPAQDGE--------- 565

  Fly   671 EWDRYDLDWPEFNRRAQAYLNIGIPPTVGYKYR---QIYMNFWNKELP---------DELNQIAA 723
                   :||.|::....|........:....|   ....:|||..||         |..:..|:
  Fly   566 -------EWPNFSKEDPVYYIFSTDDKIEKLARGPLAARCSFWNDYLPKVRSWAGTCDGDSGSAS 623

  Fly   724 IQEQLQKPG 732
            |..:||..|
  Fly   624 ISPRLQLLG 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_001246966.1	COesterase	153..710	CDD:278561	154/626 (25%)
		Aes	<263..>408	CDD:223730	51/181 (28%)
Ace	NP_001163600.1	COesterase	41..601	CDD:278561	154/626 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910