Protein Alignment Nlg1 and Ces1b

DIOPT Version :9

• Sequence 1: NP_001246966.1
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_001074841.1
• Gene: Ces1b / 382044
• MGIID: 3779470
• Length: 567
• Species: Mus musculus
• Alignment Length: 591
• Identity: 171/591 - (28%)
• Similarity: 274/591 - (46%)
• Gaps: 99/591 - (16%)

  Fly   158 IQVKQGRLMGITRRFQVTSGLRQ-VDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLPPVC 221
            :...||:::|   ::....|... |..|||:|:|:.|.|:.||.||....||..:|.|...||:|
Mouse    26 VDTTQGKILG---KYTSLEGFEHPVAVFLGVPFAKPPLGSLRFAPPEPAEPWSFVKNATSYPPMC 87

  Fly   222 PQK------LPDLSPHGSENMSRARHKHLSRLLPYLRTESEDCLYLNLYVPHEEPQSTPKQYAVL 280
            .|.      |.|:.....|:            :|.|  .||||||||:|.|.:..:|:  ...|:
Mouse    88 SQDAVAVQLLSDMLSTKKES------------IPPL--FSEDCLYLNIYSPADLTKSS--LLPVM 136

  Fly   281 VYLHGESFEWNSGNPYDGSVLSSYGEVIVVTVNYRLGVLGFLRPSIDAHNIANYALLDQIAALHW 345
            |::||........:.|:|..||::..|:|||:.||||:.|..... |.|:..|:|.|||:|||.|
Mouse   137 VWIHGGGLMTGGASLYNGLALSAHENVVVVTIQYRLGIWGLFSTG-DEHSRGNWAHLDQLAALRW 200

  Fly   346 IKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASGLFHRAILMSGSAMSDWAASNQSLQLTM 410
            :::||..|||:...||:.|.|.|...|:.|::||:|..||||||..|...:       :::.:|:
Mouse   201 VQDNIANFGGNPDSVTVFGSSAGGVSVSVLVLSPLAKNLFHRAISESSVVL-------ENIVITL 258

  Fly   411 QIAHALECPLNEHVEA------EDDDVLLDCLRHRRYQDILHIPTAL-----------TQFSTSL 458
            .:   :.|.|::.:..      .....::.|||.:...::|.|...|           .:.:||:
Mouse   259 DL---VACDLSQMIATVSGCNDTSSTAMVQCLRQKTENELLEITVKLEVTKVGGAASAKKDNTSM 320

  Fly   459 GPIVDGHVIPNQPYKVMGHYTEHFSRYDLLFGITESE---SYHTLAALALEEGLRENERDNLLRF 520
            ..::||.|:|..|.:::..  :.||....:.|..:.|   ...|:....|.||....|..:||..
Mouse   321 STVIDGVVLPKAPEEILAE--KSFSTVPYIVGFNKQEFGWIIPTMLGDLLSEGKMNEETASLLLR 383

  Fly   521 YMQSRFDIRPDLALAATLKKYQDMYNNPIKATNLEHRDVVLDILSDA--RVVGPLLQTGMFHADV 583
            ...|..:|...| :.|.::||....::|.|     .||::||:.||.  .:...||...:..|.|
Mouse   384 RFHSDLNISESL-IPAVIEKYLRGTDDPAK-----KRDLLLDMFSDVFFGIPAVLLSRSLRDAGV 442

  Fly   584 NRRNYMYVFGHNSATGPFA--HLPHSI---MGEELAFIFGAPLAAAGPFPSGNYTVQEKLLSEAV 643
            :  .|||.|.:..:   |.  ..|.::   .|:|:..:||.||...|.      :.:|..||:.|
Mouse   443 S--TYMYEFRYRPS---FVSDKRPQTVEGDHGDEIFSVFGIPLLKEGT------SEEETNLSKMV 496

  Fly   644 MAYWTNFVKTGNPKAPWKGIFINSHALEWDRYDLDWPEFNRRAQAYLNIGIPPTVGYKYRQIYMN 708
            |.:|.||.:.|||         |...|.      .|||::.: :.||.||.......:.:...:.
Mouse   497 MKFWANFARNGNP---------NGEGLP------HWPEYDEK-EGYLQIGATTQQAQRLKAEEVA 545

  Fly   709 FWNKEL 714
            ||.:.|
Mouse   546 FWTELL 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_001246966.1	COesterase	153..710	CDD:278561	168/585 (29%)
		Aes	<263..>408	CDD:223730	53/144 (37%)
Ces1b	NP_001074841.1	COesterase	19..547	CDD:278561	168/585 (29%)
		Aes	<121..>239	CDD:223730	46/120 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810