Protein Alignment Nlg1 and Ces1b

DIOPT Version :10

• Sequence 1: NP_731172.2
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_001074841.1
• Gene: Ces1b / 382044
• MGIID: 3779470
• Length: 567
• Species: Mus musculus
• Alignment Length: 591
• Identity: 171/591 - (28%)
• Similarity: 274/591 - (46%)
• Gaps: 99/591 - (16%)

  Fly   158 IQVKQGRLMGITRRFQVTSGLRQ-VDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLPPVC 221
            :...||:::|   ::....|... |..|||:|:|:.|.|:.||.||....||..:|.|...||:|
Mouse    26 VDTTQGKILG---KYTSLEGFEHPVAVFLGVPFAKPPLGSLRFAPPEPAEPWSFVKNATSYPPMC 87

  Fly   222 PQK------LPDLSPHGSENMSRARHKHLSRLLPYLRTESEDCLYLNLYVPHEEPQSTPKQYAVL 280
            .|.      |.|:.....|:            :|.|  .||||||||:|.|.:..:|:  ...|:
Mouse    88 SQDAVAVQLLSDMLSTKKES------------IPPL--FSEDCLYLNIYSPADLTKSS--LLPVM 136

  Fly   281 VYLHGESFEWNSGNPYDGSVLSSYGEVIVVTVNYRLGVLGFLRPSIDAHNIANYALLDQIAALHW 345
            |::||........:.|:|..||::..|:|||:.||||:.|..... |.|:..|:|.|||:|||.|
Mouse   137 VWIHGGGLMTGGASLYNGLALSAHENVVVVTIQYRLGIWGLFSTG-DEHSRGNWAHLDQLAALRW 200

  Fly   346 IKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASGLFHRAILMSGSAMSDWAASNQSLQLTM 410
            :::||..|||:...||:.|.|.|...|:.|::||:|..||||||..|...:       :::.:|:
Mouse   201 VQDNIANFGGNPDSVTVFGSSAGGVSVSVLVLSPLAKNLFHRAISESSVVL-------ENIVITL 258

  Fly   411 QIAHALECPLNEHVEA------EDDDVLLDCLRHRRYQDILHIPTAL-----------TQFSTSL 458
            .:   :.|.|::.:..      .....::.|||.:...::|.|...|           .:.:||:
Mouse   259 DL---VACDLSQMIATVSGCNDTSSTAMVQCLRQKTENELLEITVKLEVTKVGGAASAKKDNTSM 320

  Fly   459 GPIVDGHVIPNQPYKVMGHYTEHFSRYDLLFGITESE---SYHTLAALALEEGLRENERDNLLRF 520
            ..::||.|:|..|.:::..  :.||....:.|..:.|   ...|:....|.||....|..:||..
Mouse   321 STVIDGVVLPKAPEEILAE--KSFSTVPYIVGFNKQEFGWIIPTMLGDLLSEGKMNEETASLLLR 383

  Fly   521 YMQSRFDIRPDLALAATLKKYQDMYNNPIKATNLEHRDVVLDILSDA--RVVGPLLQTGMFHADV 583
            ...|..:|...| :.|.::||....::|.|     .||::||:.||.  .:...||...:..|.|
Mouse   384 RFHSDLNISESL-IPAVIEKYLRGTDDPAK-----KRDLLLDMFSDVFFGIPAVLLSRSLRDAGV 442

  Fly   584 NRRNYMYVFGHNSATGPFA--HLPHSI---MGEELAFIFGAPLAAAGPFPSGNYTVQEKLLSEAV 643
            :  .|||.|.:..:   |.  ..|.::   .|:|:..:||.||...|.      :.:|..||:.|
Mouse   443 S--TYMYEFRYRPS---FVSDKRPQTVEGDHGDEIFSVFGIPLLKEGT------SEEETNLSKMV 496

  Fly   644 MAYWTNFVKTGNPKAPWKGIFINSHALEWDRYDLDWPEFNRRAQAYLNIGIPPTVGYKYRQIYMN 708
            |.:|.||.:.|||         |...|.      .|||::.: :.||.||.......:.:...:.
Mouse   497 MKFWANFARNGNP---------NGEGLP------HWPEYDEK-EGYLQIGATTQQAQRLKAEEVA 545

  Fly   709 FWNKEL 714
            ||.:.|
Mouse   546 FWTELL 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_731172.2	COesterase	157..710	CDD:395084	168/585 (29%)
Ces1b	NP_001074841.1	COesterase	22..547	CDD:395084	168/585 (29%)