DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nlg1 and SPAPB18E9.04c

DIOPT Version :9

Sequence 1:	NP_001246966.1	Gene:	Nlg1 / 40913	FlyBaseID:	FBgn0051146	Length:	1354	Species:	Drosophila melanogaster
Sequence 2:	NP_001018272.1	Gene:	SPAPB18E9.04c / 3361427	PomBaseID:	SPAPB18E9.04c	Length:	800	Species:	Schizosaccharomyces pombe

Alignment Length:	538	Identity:	112/538 - (20%)
Similarity:	172/538 - (31%)	Gaps:	154/538 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   891 CSKSRDGDDSFVLEMTRKSNTYEAIKTG-------QRSLSCSTVDTHTKVCEWMSSQEAPKSGSF 948
            |:.........:.|.|  |:|..|..||       ..|.||:|           |:...|..||.
pombe    77 CTTDTSASTPIITEST--SSTSSASTTGSSSSPLPSTSTSCTT-----------STSIPPTGGSS 128

  Fly   949 NTATP--PPQPILSDGRLIICQDIEVADAALLIPQHMHEPQHYEMLLQRQHSALTEPSDEILQQQ 1011
            :.:||  |..|..|           .:..::.||     |..........:...|..:.......
pombe   129 SLSTPITPTVPPTS-----------TSSTSIPIP-----PTSTSSTDTNSNPLPTTSTSCTTSTS 177

  Fly  1012 YPLRNHSHSHSDPVDMILAADEQVTSFVHADDVDINVTSRDDSD-GLEVIPLTSAQQLELLRQRN 1075
            .|....|.|.|.|:...:..    || ..:..:.|..||...:| ....:|.||.       ...
pombe   178 IPPTGGSSSLSTPITPTVPP----TS-TSSTSIPIPPTSTSSTDTNSSPLPTTST-------SCT 230

  Fly  1076 YPKVLPTEQDLINSSYKRNSLPPQNFNA---PLPPPRTISNTLGRRRRDSSNITTSPL-QVARDC 1136
            ....:||......|:....::||.:.::   |:||..|          .|::..:||| ..:..|
pombe   231 TSTSIPTGGSSSLSTPITPTVPPTSTSSTSIPIPPTST----------SSTDTNSSPLPTTSTSC 285

  Fly  1137 GGEDEDLKEPQITQNTLI------VGPIVPKSPASSLKRVKRMP----------ESSAMTALSGS 1185
                        |.:|.|      ..|:.|..|.:|.......|          .||.:.:.|.|
pombe   286 ------------TTSTSIPPTGNSTTPVTPTVPPTSTSSTSTPPPPASTSSTGTSSSPLPSTSTS 338

  Fly  1186 FQSFEAVPPAHETT-------PPQGGERTECIYAIRPSPGSCSWAAPNGDLYAQPMKSSSR---- 1239
            ..:..::||...:|       ||.....|    :..|.|.|.|....:    :.|:.|:|.
pombe   339 CTTSTSIPPTGNSTTPVTPTVPPTSTSST----STPPPPASTSSTGTS----SSPLLSTSTSCTT 395

  Fly  1240 --------NSLIP-RPTKPAESQS----------------QATPAGPAGESLGSTGMATASRIPQ 1279
                    ||..| .||.|..|.|                .:||.  ....|.:|...|::.:|.
pombe   396 STSIPPTGNSTTPVTPTVPPTSSSTPLTTTNCTTSTSVPYTSTPV--TSTPLATTNCTTSTSVPY 458

  Fly  1280 LQRQASGKDLQARTATDN-----TANPLGCQPRTDSTISSGSSASYASTTDSSS----SSSTGTV 1335
            .....:...|.....|.:     |:.|:...|.|.:..::.:|..|.||..:||    ||||...
pombe   459 TSTPVTSTPLTTTNCTTSTSIPYTSTPVTSTPLTTTNCTTSTSVPYTSTPVTSSNYTISSSTPVT 523

  Fly  1336 RTELQQFQPAPGRSITTN 1353
            .|      |....:.||:
pombe   524 ST------PVTTTNCTTS 535

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
Nlg1	NP_001246966.1	COesterase	153..710	CDD:278561
Nlg1	NP_001246966.1	Aes	<263..>408	CDD:223730
SPAPB18E9.04c	NP_001018272.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43903
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100