Protein Alignment Nlg1 and Nlg3

DIOPT Version :10

• Sequence 1: NP_731172.2
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: XP_061500330.1
• Gene: Nlg3 / 3290865
• VectorBaseID: AGAMI1_000316
• Length: 952
• Species: Anopheles gambiae
• Alignment Length: 960
• Identity: 301/960 - (31%)
• Similarity: 455/960 - (47%)
• Gaps: 171/960 - (17%)

  Fly   119 NTTAAVLATDEGSSEHEPSTTHHPERRHVVPDKLQYTQEIQVKQGRLMGITRRFQVTSGLRQVDQ 183
            :|::.::.|..|:..   .|..|.:.||:.|                               |:.
Mosquito    60 STSSRIVHTKYGAVS---GTIEHLDGRHLDP-------------------------------VEA 90

  Fly   184 FLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLPPVCPQKLPDL--SPHGSENMSRARHKHLSR 246
            |.|:|||..|.||.|||||.....|.|:|.|....|||||:|||:  .....|.|.|.|.::|.|
Mosquito    91 FRGVPYASPPVGNLRFMPPVTGALWSGVKKADRFSPVCPQRLPDIYNETAALERMPRGRLEYLRR 155

  Fly   247 LLPYLRTESEDCLYLNLYVPHE----EPQSTPKQYAVLVYLHGESFEWNSGNPYDGSVLSSYGEV 307
            ||||||.:||||||||:|||.:    |..||.| |||:|::||||:|||||||||||||:|||::
Mosquito   156 LLPYLRNQSEDCLYLNIYVPTQAGSRESSSTSK-YAVVVFVHGESYEWNSGNPYDGSVLASYGQI 219

  Fly   308 IVVTVNYRLGVLGFLRPSIDAHN--IANYALLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAA 370
            :|||:|||||:||||..::|..:  .|||.|:|.|||||||:|||||||||...|||.||.||||
Mosquito   220 LVVTINYRLGILGFLNANVDRFSKAPANYGLMDIIAALHWIQENIEAFGGDPKSVTLAGHGTGAA 284

  Fly   371 CVNYLMVS-PVASG-LFHRAILMSGSAMSDWAASNQSLQLTMQIAHALEC-PLNEHVEAEDDDVL 432
            ||::|:.| .|..| ||||||:||||.::.|:...:..:....::|.:.| |...|      .:|
Mosquito   285 CVHFLIASAAVPEGLLFHRAIMMSGSGLAPWSLVGEPAKFAAYVSHHVNCSPDLPH------QLL 343

  Fly   433 LDCLRHRRYQDILHIPTALTQFSTSLGPIVDGHVIPNQPYKVMG--HYTEH-------------- 481
            |.|||.:..:|||........|..:.||.|||.||.....:.|.  ||:::
Mosquito   344 LKCLRDKPLEDILSTSVRAPDFGNAFGPSVDGVVIDTGEIQQMDGTHYSDYSGNPAATKPSAHIH 408

  Fly   482 ------------------FSRYDLLFGITESESYHTLAALALEEGLRENERDNLLRFYMQSRFDI 528
                              .|:||||.|:|.:|:|....:..::.|:..:.|..:|:.|::|.:..
Mosquito   409 NTLNTINAILLRKLAINKLSKYDLLVGVTRAEAYFAFNSEDVQYGIEADRRAKILKNYVRSTYSF 473

  Fly   529 RPDLALAATLKKYQDMYNNPIKATNLEHRDVVLDILSDARVVGPLLQTGMFHADVNRRNYMYVFG 593
            ..:..||..:.:|.| :..|::.. :..||..|:.|||||:|.|.:||...|:..:|.:::|||.
Mosquito   474 HLNEILATIVNEYTD-WERPVQHP-INIRDETLEALSDARIVAPAVQTADLHSADHRNSFLYVFD 536

  Fly   594 HNSATGPFAHLPHSIMGEELAFIFGAPLAAAGPFPSGNYTVQEKLLSEAVMAYWTNFVKTGNPKA 658
            :.:..|.|......|.||:|.::|||||.......:.|||..|..||||||.||:||::||||..
Mosquito   537 YQTKFGDFPQRQGCIHGEDLPYLFGAPLVGGFNHFTRNYTKSEIALSEAVMIYWSNFIRTGNPNE 601

  Fly   659 PWKGIFINSHALEWDRY-DLDWPEFNRRAQAYLNIGIPPTVGYKYRQIYMNFWNKELPDELNQIA 722
            ..:    |.|..:..|: :::|..:....:.|||:...|.:...||...::||...:||
Mosquito   602 QLE----NDHVRDRTRFKNIEWTPYESVHKKYLNLDTKPKLKNHYRAHRLSFWLNLVPD------ 656

  Fly   723 AIQEQLQKPG-QEVITGH--MSKYGPRDHGAEDPVRTLKLLLQEPSLAGPTQSGESTETAAENMY 784
                 |.||| .:|.:||  :.........|...|:.|....::|:..|...:..:|:..:...:
Mosquito   657 -----LHKPGNDDVPSGHHELESDDEEQPAALPTVKPLNPPQRDPATIGSNYTLFTTQVFSLLNF 716

  Fly   785 NAPPTFGHVHKMQGGSDFEDLVTSTNSLESGEDH--------------PQAPPETVAKSEATMQL 835
            ::.....:..:...|:.....||:.:| |.|:|.              ..:..:..|.....:.:
Mosquito   717 SSYGILPNGSRHYPGTRPVHPVTAESS-EGGDDDGGAAGGGAGGAGGMSSSQEDGFAAYSTALSV 780

  Fly   836 LIALITIIIVLNLLIY-GTFLLRQRRRRAKALPFPAPKLGGTILSYDGANDE-ELKRCSKSRDGD 898
            .||:...:::||:||: |.:..|.:.|      ...|:.||..:...|.:.. :.|:.:::....
Mosquito   781 TIAIGCSLLILNVLIFAGVYYQRDKTR------LNEPRGGGPGMGGPGGHGTLQTKKRNENGQMP 839

  Fly   899 DSFVLEMTRKSNTYEAIKTGQRSLSCSTVDTHTKVCEWMSSQEAPKSGSFNTATPPPQPILSDGR 963
            ::...|:  :|.|..|      ....||:..|............|:........|||
Mosquito   840 NNICGEL--ESLTIHA------KADPSTILGHHHPALQHHQMPPPEFADLPQRAPPP-------- 888

  Fly   964 LIICQDIEVADAALLIPQHMHE---------PQHYEMLLQRQHSALTEPS 1004
                            |:|:..         |.|...|:......||:.|
Mosquito   889 ----------------PKHLKSVPGDGGGMLPAHALQLIGSNCGTLTKKS 922

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_731172.2	COesterase	157..710	CDD:395084	235/598 (39%)
Nlg3	XP_061500330.1	None