Protein Alignment Nlg1 and Ces5a

DIOPT Version :10

• Sequence 1: NP_731172.2
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_001012056.2
• Gene: Ces5a / 307660
• RGDID: 1549717
• Length: 575
• Species: Rattus norvegicus
• Alignment Length: 610
• Identity: 186/610 - (30%)
• Similarity: 282/610 - (46%)
• Gaps: 122/610 - (20%)

  Fly   137 STTHHPERRHVVPDKLQYTQ--EIQVKQGRLMGITRRFQVTSGLRQVDQFLGLPYAEAPTGNRRF 199
            |.|..|.|         ||:  .:|.||..::|         .|..|:.|||:|:|..|.|..||
  Rat    26 SVTEEPHR---------YTRLGWVQGKQATVLG---------RLEPVNVFLGIPFAAPPLGPLRF 72

  Fly   200 MPPGAPLPWQGLKIARHLPPVCPQKLPDLSPHGSENMSRARHKHLSRLLPYLRTESEDCLYLNLY 264
            ..|..|:||..|:.|...|.||.|.|..|..:  :|:.:..:..|.        .||||||||:|
  Rat    73 SNPQPPIPWHDLREATTYPNVCFQNLEWLFIY--QNLLKVHYPKLG--------VSEDCLYLNIY 127

  Fly   265 VPHEEPQSTPKQYA-------VLVYLHGESFEWNSGNPYDGSVLSSYGEVIVVTVNYRLGVLGFL 322
            .|         .||       |::::.|..||..|.:.:|||.|::|.:|::||:.||||:.||.
  Rat   128 AP---------AYANDGSRLPVMMWIPGGGFETGSASIFDGSALAAYEDVLIVTIQYRLGIFGFF 183

  Fly   323 RPSIDAHNIANYALLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASGLFHR 387
            ... :.|...|:|..||:|||.|::|||..|||:...||:.|.|.||..::.|::||:::|||||
  Rat   184 NTQ-NQHAPGNWAFQDQLAALQWVRENINYFGGNPDSVTIFGGSAGAISISSLILSPLSAGLFHR 247

  Fly   388 AILMSGSAMSDWAASNQSLQ-LTMQIAHALE-----CPLNEHVEAEDDDVLLDCLRHRRYQDILH 446
            ||:.||.|:.      .||: ...::.|.|:     |..|    ..|..|||.|||.:...::|
  Rat   248 AIMQSGVAII------PSLKNFDDELKHGLQVVADVCKCN----VSDSKVLLKCLREKSSLELL- 301

  Fly   447 IPTALTQFSTSLGPIVDGHVIPNQPYKVMGHYTEHFSRYDLLFGITESESYHTLAALALEE---G 508
               :|.|.:.:...:|||...|.:|.:::...|  |.....:.|:...|..:.|......|   |
  Rat   302 ---SLGQKTKAFTRVVDGSFFPEEPMELLSQKT--FKTVPSIIGVNNQECGYILPMREAPEILFG 361

  Fly   509 LRENERDNLLRFYMQSRFDIRPD-LALAATLKKYQDMYNNPIKATNLEHRDVVLDILSDARVVGP 572
            ..|:....|:...:.    |.|. :.:.|     :|.::.....|::  ||.:||:..|...|.|
  Rat   362 SNESTALTLIHVLLH----IPPQYMHIVA-----KDYFHGKHSLTDI--RDTLLDLFGDVFFVVP 415

  Fly   573 LLQTGMFHADVNRRNYMYVFGHN----SATGP-FAHLPHSIMGEELAFIFGAPLAAAGPFPSGNY 632
            .|.|...|.|.....|.|.|.|.    ..|.| |....|:   :|:.|:||      |||..|:.
  Rat   416 GLVTARNHRDAGGPVYFYEFQHRPNCFQNTRPAFVKADHT---DEIRFVFG------GPFLEGDV 471

  Fly   633 ------TVQEKLLSEAVMAYWTNFVKTGNPKAPWKGIFINSHALEWDRYDLD-WPEFNRRAQAYL 690
                  |..|||||..:|:||.||.::|:|...                ||. ||.:::. ::||
  Rat   472 VMFEEATEDEKLLSRKMMSYWANFARSGDPNGD----------------DLPLWPAYDQN-ESYL 519

  Fly   691 NIGIPPTVGYKYRQIYMNFWNKELP 715
            .:.:..:.|::.:...:.||...||
  Rat   520 KLDVNISTGWRLKDRRVEFWTDTLP 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_731172.2	COesterase	157..710	CDD:395084	176/581 (30%)
Ces5a	NP_001012056.2	COesterase	29..539	CDD:395084	180/600 (30%)