Protein Alignment Nlg1 and Ces2g

DIOPT Version :10

• Sequence 1: NP_731172.2
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_001099645.1
• Gene: Ces2g / 291952
• RGDID: 1308358
• Length: 560
• Species: Rattus norvegicus
• Alignment Length: 605
• Identity: 189/605 - (31%)
• Similarity: 282/605 - (46%)
• Gaps: 97/605 - (16%)

  Fly   140 HHPERRHVVPDKLQYTQEIQVKQGRLMGITRRFQVTSGLRQVDQFLGLPYAEAPTGNRRFMPPGA 204
            |.||..   |.:..:|.::|.|      :|......||   |..|||:|:|:||.|..||.||.|
  Rat    28 HSPESS---PIRNTHTGQVQGK------LTHSKDFKSG---VHTFLGIPFAKAPVGPLRFAPPEA 80

  Fly   205 PLPWQGLKIARHLPPVCPQKLPDLSPHGSENMSRARHKHLSRLLPYLRTESEDCLYLNLYVP--- 266
            |.||.|::.......:|||.:         .|:....|.:...||.: :.||||||||:|.|
  Rat    81 PEPWSGVRDGTSQSNICPQNV---------RMNMEGLKEMKLTLPPV-SMSEDCLYLNIYAPAHA 135

  Fly   267 HEEPQSTPKQYAVLVYLHGESFEWNSGNPYDGSVLSSYGEVIVVTVNYRLGVLGFLRPSIDAHNI 331
            ||     .....|:|::||.:......:.||||:|::..:|:|||:.||||||||.... |.|..
  Rat   136 HE-----GSHLPVMVWIHGGALTVGMASMYDGSMLAATEDVVVVTIQYRLGVLGFFSTG-DHHAR 194

  Fly   332 ANYALLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASGLFHRAILMSGSAM 396
            .|:..|||:|||.|:::||..|||:...||:.|.|.|...|:..:|||::.|||||||:.||.|:
  Rat   195 GNWGYLDQVAALRWVQQNIAHFGGNPDCVTIFGESAGGLSVSSHVVSPMSKGLFHRAIMESGVAL 259

  Fly   397 SDWAASNQSLQLTMQIAHALECPLNEHVEAEDDDVLLDCLRHRRYQDILHIPTALTQFSTSLGPI 461
            ......|.|..:...:.....|      ||.|.:.|:.|||.:..:.|    |.:::....:..:
  Rat   260 MPGTIFNFSEMVYQMVVKLSGC------EAMDPESLVHCLRGKSEEQI----TVISKEFQMIPAV 314

  Fly   462 VDGHVIPNQPYKVMGHYTEHFSRYDLLFGITESE-SYHTLAALALEEGLRENERDNLLRFYMQSR 525
            |||..:||.|.:::.  :..|.....:.|....| .:.....:...:.::...|:||..|..
  Rat   315 VDGEFLPNHPQELLA--SADFHPVPSIIGFNNDEYGWIVPKVIGSAQTIKGITRENLQAFLK--- 374

  Fly   526 FDIRPDLALA-----ATLKKYQDMYNNP--IKATNLEHRDVVLDILSDARVVGPLLQTGMF---H 580
             |..|.:.|.     ..:::|.....:|  ::|...|       ::.|...|.|.||...|   |
  Rat   375 -DTAPQMMLPPECSDLLMEEYMGDIEDPQTLQAQFTE-------MMEDFMFVIPSLQVARFQRSH 431

  Fly   581 ADVNRRNYMYVFGHNSATGPFAHLPH--SIMGEELAFIFGAPLAAAGPFPSG---NYTVQEKLLS 640
            |.|    |.|.|.|.|:.......||  :..|:|:.|:||:       |..|   |.|..||||:
  Rat   432 APV----YFYEFQHQSSFLKDIRPPHVKADHGDEVPFVFGS-------FFWGMKLNLTEGEKLLN 485

  Fly   641 EAVMAYWTNFVKTGNPKAPWKGIFINSHALEWDRYDLDWPEFNRRAQAYLNIGIPPTVGYKYRQI 705
            ..:|.||.||.:.|||         ||::|.:      ||.|:...| ||.:...|.||...:..
  Rat   486 RRMMKYWANFARYGNP---------NSNSLPY------WPVFDYDEQ-YLQLNTQPAVGRIQKAR 534

  Fly   706 YMNFWNKELPDELNQIAAIQ 725
            .:.||.|.||.::.::...|
  Rat   535 KLQFWTKTLPQKIEELKRSQ 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_731172.2	COesterase	157..710	CDD:395084	178/571 (31%)
Ces2g	NP_001099645.1	COesterase	32..539	CDD:395084	180/584 (31%)