Protein Alignment Nlg1 and Cel

DIOPT Version :10

• Sequence 1: NP_731172.2
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_058693.2
• Gene: Cel / 24254
• RGDID: 2331
• Length: 612
• Species: Rattus norvegicus
• Alignment Length: 696
• Identity: 186/696 - (26%)
• Similarity: 277/696 - (39%)
• Gaps: 168/696 - (24%)

  Fly   158 IQVKQGRLMGITRRFQVTSGLRQVDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLPPVCP 222
            :..:.|.:.|:.::..:..| ..||.|.|:|:|.|.|.......||    |||...|......|.
  Rat    26 VYTEGGFVEGVNKKLSLLGG-DSVDIFKGIPFATAKTLENPQRHPG----WQGTLKATDFKKRCL 85

  Fly   223 Q-KLPDLSPHGSENMSRARHKHLSRLLPYLRTESEDCLYLNLYVPHEEPQSTPKQYAVLVYLHGE 286
            | .:.....:|                      .|||||||::||....| ......|:|:::|.
  Rat    86 QATITQDDTYG----------------------QEDCLYLNIWVPQGRKQ-VSHDLPVMVWIYGG 127

  Fly   287 SFEWNSGNP--------YDGSVLSSYGEVIVVTVNYRLGVLGFLRPSIDAHNIANYALLDQIAAL 343
            :|...||..        |||..:::.|.|||||.|||:|.||||... ||:...|:.|.||..|:
  Rat   128 AFLMGSGQGANFLKNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTG-DANLPGNFGLRDQHMAI 191

  Fly   344 HWIKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASGLFHRAILMSGSAMSDWAASNQSLQL 408
            .|:|.||.|||||...:|:.|.|.|||.|:...:||...||..|||..||.|:|.||.....|..
  Rat   192 AWVKRNIAAFGGDPDNITIFGESAGAASVSLQTLSPYNKGLIRRAISQSGVALSPWAIQENPLFW 256

  Fly   409 TMQIAHALECPLNEHVEAEDDDVLLDCLRHRRYQDILHIPTALT-QFSTSLG------------- 459
            ...||..:.||      .||...:..||:       :..|.||| .:...|.
  Rat   257 AKTIAKKVGCP------TEDTAKMAGCLK-------ITDPRALTLAYRLPLKSQEYPIVHYLAFI 308

  Fly   460 PIVDGHVIPNQPYKVMGHYTEHFSRYDLLFGITESES--YHTLAALALEEGLRENERDNLLRFY- 521
            |:|||..||:.|..:.    ::.:..|.|.||.:.:.  :.|:...|:::..::...::..|..
  Rat   309 PVVDGDFIPDDPINLY----DNAADIDYLAGINDMDGHLFATVDVPAIDKAKQDVTEEDFYRLVS 369

  Fly   522 ----------MQSRFDIRPDLALAATLKKYQDMYNNPIKATNLEHRDVVL--DILSDARVVGPLL 574
                      .|:.|||            |.:.:.......|::...|..  |||.       |:
  Rat   370 GHTVAKGLKGTQATFDI------------YTESWAQDPSQENMKKTVVAFETDILF-------LI 415

  Fly   575 QTGM------FHADVNRRNYMYVFGHNSATGPFAHLPHSIMGEELAFIFGAPLAAAGPFPSGNYT 633
            .|.|      .||. :.:.|.|:|.|.|....:.....:...::|.::||.|.|.    |.| |.
  Rat   416 PTEMALAQHRAHAK-SAKTYSYLFSHPSRMPIYPKWMGADHADDLQYVFGKPFAT----PLG-YR 474

  Fly   634 VQEKLLSEAVMAYWTNFVKTGNP---KAPWKGIFINSHALEWDRYDLDWPEFNRRAQAYLNIG-- 693
            .|::.:|:|::||||||.|:|:|   .:|     :.:|          |..:......||:|.
  Rat   475 AQDRTVSKAMIAYWTNFAKSGDPNMGNSP-----VPTH----------WYPYTTENGNYLDINKK 524

  Fly   694 IPPTVGYKY-RQIYMNFWNKELPDELNQIAAIQEQLQKPGQEVITGHMSKYGPRDHGAEDPVRTL 757
            |..|...:: |:.::.||           |...|.|    ..|:..|..   |.|.....||..
  Rat   525 ITSTSMKEHLREKFLKFW-----------AVTFEML----PTVVGDHTP---PEDDSEAAPVPP- 570

  Fly   758 KLLLQEPSLAGPTQSGESTETAAENMYNAPPTFGHVHKMQGGSDFE 803
                .:.|...|....:.::|..     .|||    ...|.|...|
  Rat   571 ----TDDSQVVPVPPTDDSQTTP-----VPPT----DNSQAGDSVE 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_731172.2	COesterase	157..710	CDD:395084	166/601 (28%)
Cel	NP_058693.2	COesterase	26..542	CDD:395084	166/601 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	553..612		14/68 (21%)
		4 X 11 AA tandem repeats, O-glycosylated region	556..599		12/59 (20%)