Protein Alignment Nlg1 and Ces2e

DIOPT Version :9

• Sequence 1: NP_001246966.1
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_001157228.1
• Gene: Ces2e / 234673
• MGIID: 2443170
• Length: 559
• Species: Mus musculus
• Alignment Length: 583
• Identity: 182/583 - (31%)
• Similarity: 273/583 - (46%)
• Gaps: 118/583 - (20%)

  Fly   181 VDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLPPVCPQKLPDLSPHGSENMSRARHKHLS 245
            |..|||:|:|:.|.|..||.||.||.||.|::.....|.:|   |.:.:..|||::     |.::
Mouse    55 VHTFLGIPFAKPPVGPLRFAPPEAPEPWSGVRDGTSHPNMC---LQNDNLMGSEDL-----KMMN 111

  Fly   246 RLLPYLRTESEDCLYLNLYVP-H-EEPQSTPKQYAVLVYLHGESFEWNSGNPYDGSVLSSYGEVI 308
            .:||.: :.||||||||:||| | .|..:.|    |:|::||.:......:.||||:|::..:|:
Mouse   112 LILPPI-SMSEDCLYLNIYVPAHAHEGSNLP----VMVWIHGGALTVGMASMYDGSMLAATEDVV 171

  Fly   309 VVTVNYRLGVLGFLRPSIDAHNIANYALLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACVN 373
            ||.:.||||||||.... |.|...|:..|||:|||.|:::||..|||:..|||:.|.|.|...|:
Mouse   172 VVAIQYRLGVLGFFSTG-DQHAKGNWGYLDQVAALRWVQQNIVHFGGNPDRVTIFGESAGGTSVS 235

  Fly   374 YLMVSPVASGLFHRAILMSGSAMSDWAASNQSLQLTMQIAHALECPLNEHVEAEDDDVLLDCLRH 438
            ..:|||::.||||.||:.||.|:.....|:.|..:...:|:...|      .|.:.:.|:.|||.
Mouse   236 SHVVSPMSQGLFHGAIMESGVAVLPDLISSSSEMVHRIVANLSGC------AAVNSETLMCCLRG 294

  Fly   439 RRYQDILHIPTALTQFSTSLGPIVDGHVIPNQPYKVMGHYTEHFSRYDLLFGITESE-------- 495
            :...::|    |:.:....:..:|||..:|..|.::|.  ::.|.....:.||...|
Mouse   295 KNEAEML----AINKVFKIIPGVVDGEFLPKHPQELMA--SKDFHPVPSIIGINNDEYGWILPTI 353

  Fly   496 ----------SYHTLAAL----ALEEGLRENERDNLLRFYMQSRFDIRPDLALAATLKKYQDMYN 546
                      :..||.|:    ||:..|.....|.|:..||....|  |:...|    ::::|
Mouse   354 MDPAQKIEEITRKTLPAVLKSTALKMMLPPECGDLLMEEYMGDTED--PETLQA----QFREM-- 410

  Fly   547 NPIKATNLEHRDVVLDILSDARVVGPLLQTGMF---HADVNRRNYMYVFGHNSA-----TGPFAH 603
                             ..|...|.|.||...|   ||.|    |.|.|.|..:     ..|:..
Mouse   411 -----------------KGDFMFVIPALQVAHFQRSHAPV----YFYEFQHRPSFFKDFRPPYVK 454

  Fly   604 LPHSIMGEELAFIFGAPLAAAGPFPSGN----YTVQEKLLSEAVMAYWTNFVKTGNPKAPWKGIF 664
            ..|   |:|:..:||        :..||    ||.:|:.||..:|.||.||.:.|||
Mouse   455 ADH---GDEIFLVFG--------YQFGNIKLPYTEEEEQLSRRIMKYWANFARHGNP-------- 500

  Fly   665 INSHALEWDRYDLDWPEFNRRAQAYLNIGIPPTVGYKYRQIYMNFWNKELPDELNQIAAIQEQ 727
             ||..|.:      ||..:...| ||.:.|.|:||...:...:.||.|.||.::.::...||:
Mouse   501 -NSEGLPY------WPVMDHDEQ-YLQLDIQPSVGRALKARRLQFWTKTLPQKIQELKGSQER 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_001246966.1	COesterase	153..710	CDD:278561	175/564 (31%)
		Aes	<263..>408	CDD:223730	62/146 (42%)
Ces2e	NP_001157228.1	COesterase	30..538	CDD:278561	175/564 (31%)
		Aes	<128..>231	CDD:223730	46/107 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810