Protein Alignment Nlg1 and Ces2b

DIOPT Version :10

• Sequence 1: NP_731172.2
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_937814.1
• Gene: Ces2b / 234669
• MGIID: 2448547
• Length: 556
• Species: Mus musculus
• Alignment Length: 565
• Identity: 176/565 - (31%)
• Similarity: 264/565 - (46%)
• Gaps: 87/565 - (15%)

  Fly   181 VDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLPPVCPQKLPDLSPHGSENMSRARHKHLS 245
            |..|||:|:|:.|.|..||.||.||.||.|::.....|.:|.|.|..:             |.:.
Mouse    57 VHTFLGIPFAKPPVGPLRFAPPEAPEPWSGVRDGTAHPAMCLQNLGVM-------------KEIK 108

  Fly   246 RLLPYLRTESEDCLYLNLYVP-H-EEPQSTPKQYAVLVYLHGESFEWNSGNPYDGSVLSSYGEVI 308
            ..||.:.| ||||||||:|.| | .|..:.|    |:|::||........:.||||:|::..:::
Mouse   109 LKLPPVST-SEDCLYLNIYTPAHAHEGSNLP----VMVWIHGGGLVAGMASMYDGSLLAAIEDLV 168

  Fly   309 VVTVNYRLGVLGFLRPSIDAHNIANYALLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACVN 373
            |||:.||||||||.... |.|...|:..|||:|||.||::||..|||...|||:.|.|.|...|:
Mouse   169 VVTIQYRLGVLGFFSTG-DQHARGNWGFLDQVAALRWIQQNIAHFGGKPDRVTIFGESAGGTSVS 232

  Fly   374 YLMVSPVASGLFHRAILMSGSAMSDWAASNQSLQLTMQIAHALECPLNEHVEAEDDDVLLDCLRH 438
            ..:|||::.||||.||:.||.|:..:..::.|..::..:|....|      ||.|.:.|:.|||.
Mouse   233 SHVVSPMSKGLFHGAIMESGVALLPYLITDTSEMVSTTVAKLSGC------EAMDSEALVRCLRG 291

  Fly   439 RRYQDILHIPTALTQFSTSLGPIVDGHVIPNQPYKVMGHYTEHFSRYDLLFGITESESYHTL-AA 502
            :...:||    |:.:....:..:|||...|..|.:::.  :|.|.....:.|:...|...|: ..
Mouse   292 KSEAEIL----AINKLVQMIPAVVDGEFFPRHPKELLA--SEDFHPVPSIIGVNNDEFGWTIPVV 350

  Fly   503 LALEEGLRENERDNLLRFYMQSRFDIR-----PDLALAATLKKYQDMYNNPIKATNLEHRDVVLD 562
            :...:.::|..|:||......:...:.     .||.:...:...:|.....|:.|         :
Mouse   351 MGSAQTIKEITRENLQAVLKNTTAQLMLPPECSDLLMEEYMGDTEDAQTLQIQFT---------E 406

  Fly   563 ILSDARVVGPLLQTGMF---HADVNRRNYMYVFGHNSATGPFAHLPH--SIMGEELAFIFG---- 618
            ::.|...|.|.||...|   ||.|    |.|.|.|..|:.......|  :...:|:.|:||
Mouse   407 MMEDFMFVIPALQVAYFQRSHASV----YFYEFQHQIASLKDVRPTHVKADHADEIPFVFGYFFW 467

  Fly   619 -APLAAAGPFPSGNYTVQEKLLSEAVMAYWTNFVKTGNPKAPWKGIFINSHALEWDRYDLDWPEF 682
             ..|         ::|..|||||..:|.||.||.:.|||         ||..|.:      ||..
Mouse   468 DMKL---------DFTEGEKLLSRRMMKYWANFARHGNP---------NSEGLPY------WPVM 508

  Fly   683 NRRAQAYLNIGIPPTVGYKYRQIYMNFWNKELPDELNQIAAIQEQ 727
            :...| ||.:...|.||...:...:.||.|.|..::.::.|.|::
Mouse   509 DHDEQ-YLQLDTQPAVGRALKSRRLQFWTKTLSQKIQELRASQDK 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_731172.2	COesterase	157..710	CDD:395084	170/546 (31%)
Ces2b	NP_937814.1	COesterase	32..535	CDD:395084	170/546 (31%)