Protein Alignment Nlg1 and cest-28

DIOPT Version :9

• Sequence 1: NP_001246966.1
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_504691.2
• Gene: cest-28 / 187305
• WormBaseID: WBGene00019654
• Length: 548
• Species: Caenorhabditis elegans
• Alignment Length: 630
• Identity: 157/630 - (24%)
• Similarity: 266/630 - (42%)
• Gaps: 142/630 - (22%)

  Fly   141 HPERRHVVPDKLQYTQEIQVKQGRLMGITRRFQVTSGLRQVDQFLGLPYAEAPTGNRRFMPPGAP 205
            |.||.       ::::::....|.:.|...|.    |.:.||.:||:|:|:...   ||..|...
 Worm     7 HLERE-------KHSEKLNATCGPIQGNVYRI----GDKTVDGYLGIPFAKPLV---RFKKPEPA 57

  Fly   206 LPWQGLKIARHLPPVCPQKLPDLSPHGSENMSRARHKHLSRLLPYLRTESED---CLYLNLYVPH 267
            ..|:.::......|.|||..|                 .:..:.:.:.:..|   ||.||::...
 Worm    58 GTWEEVRDCTKYGPRCPQSGP-----------------FAEAINFQKDDIPDEANCLTLNVFSKI 105

  Fly   268 EEPQSTPKQYAVLVYLHGESFEWNSGNPY-DGSVLSS--YGEVIVVTVNYRLGVLGFLRPSIDAH 329
            .:.::..|...|:||:||..:|.::...| |.||..:  ..:|:|||:|||:|:|||.... |..
 Worm   106 SDSKNFNKTRPVMVYIHGGGYECSASRDYCDYSVAGTLPLKDVVVVTLNYRVGILGFFTTG-DTV 169

  Fly   330 NIANYALLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASGLFHRAILMSGS 394
            ...|:||.|....|:||:::||:||||...:|:.|.|.|||||:.|.:||.:..||:|.|:|||.
 Worm   170 CPGNFALWDLTLGLNWIQKHIESFGGDPGNITIFGQSAGAACVDLLALSPHSRDLFNRVIVMSGG 234

  Fly   395 AMSDWA--ASNQSLQLTMQIAHALECPLNEHVEAEDDDVLLDCLRHRRYQDI-----LHIPTALT 452
            |:.::|  .:|...::..:.|..|      ..:..:...|.:.::.:..::|     ..:|.:..
 Worm   235 ALCEYAVRTANSQAKVCYEFARHL------GYDGTNSQTLFNWMKSKPLEEIEKMNGFQVPASGI 293

  Fly   453 QFSTSLGPIVDGHVIPNQ--------PYK-VMGHYTEHFSRYDLLFGITESESYHTLAALALEEG 508
            ...|   |.:|....|..        |.| :|..:.||   ..|.|.....:....|.||.
 Worm   294 LAWT---PNLDDDFFPKSLDELRIGAPKKDIMMGFAEH---EGLFFEFLIKDPTPPLEALK---- 348

  Fly   509 LRENERDNLLRFYMQSRFDIRPDLALAATLKKYQDMYNNPIKATNLEH-RDVVLDILSDARVVGP 572
            |..||      :|.:...|     ...||..|..:.|:..::.|:.:. ::.::|.:.||
 Worm   349 LYVNE------YYKKDTGD-----HFEATRNKIIEFYSRNVEDTDEKSTKERLIDFVGDA----- 397

  Fly   573 LLQTGMFHADVNRRN--------YMYVFGHNSATGPFAHLPHSIMGEELAFI-FGAP-------- 620
            |...|:|.   |.:|        ::|:|.:.:.:|         .|.:..|: |.||
 Worm   398 LFTAGVFD---NAKNCLKHGNNVWLYIFDYCNPSG---------FGNQEEFMTFVAPTHCTDLRY 450

  Fly   621 LAAAGPFPSGNYTVQEKLLSEAVMAYWTNFVKTGNPKAPWKGIFINSH-ALEWDRYDLDWPEFNR 684
            :...|.:.....|.:|..:.|.:...::||.|.|||         |.| :.||:::.||.|   |
 Worm   451 VLGEGLYSDFQPTEEEHKMIEKMTTIYSNFAKYGNP---------NEHGSSEWEKFTLDNP---R 503

  Fly   685 RAQAYLNIGIPPTVGYKYRQIYMNFWNKELPDELNQIAAIQEQLQ 729
            |   :..|..|..   |.|..|.       ||.:..:..|:.:.|
 Worm   504 R---HFQISYPRG---KMRNDYH-------PDRMKFLELIRAKNQ 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_001246966.1	COesterase	153..710	CDD:278561	150/597 (25%)
		Aes	<263..>408	CDD:223730	57/149 (38%)
cest-28	NP_504691.2	COesterase	17..516	CDD:278561	148/585 (25%)
		Aes	<112..>222	CDD:223730	47/110 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810