Protein Alignment Nlg1 and cest-8

DIOPT Version :9

• Sequence 1: NP_001246966.1
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_001359583.1
• Gene: cest-8 / 182818
• WormBaseID: WBGene00007691
• Length: 605
• Species: Caenorhabditis elegans
• Alignment Length: 632
• Identity: 145/632 - (22%)
• Similarity: 233/632 - (36%)
• Gaps: 156/632 - (24%)

  Fly   151 KLQYTQEIQVKQGRLMGITRRFQVTSGLRQVDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIAR 215
            :.|..:.|....|:|.|:.   :.:........|..:|:|:.|.||.||.||.....|.|:.
 Worm    14 EFQTLKIINTSYGKLRGMA---EWSDDANHKFTFKSVPFAKPPIGNLRFAPPQKLDHWDGIL--- 72

  Fly   216 HLPPVCPQKLPDLSPHGSENMSRARHKHLSRLLPYLRTES---EDCLYLNLYVPHEEPQSTPKQY 277
                       |.|.:.:..||.:.          |.|:|   |||||:|::...:..:|   :.
 Worm    73 -----------DASVYSAACMSNST----------LTTQSYVNEDCLYINIFTSEKCLKS---KC 113

  Fly   278 AVLVYLHGESFEWNSGNPY-DGSVLSSY--GEVIVVTVNYRLGVLGFLRPSIDAHNIANYALLDQ 339
            :|:||.||.::...|...: |..:|..|  .:||.|....||||.|.|....:|:...|..:.|.
 Worm   114 SVIVYFHGGAYNTESATMFSDRFILDRYVHEDVIFVIPAVRLGVFGQLYFGPNAYLTENLFMFDA 178

  Fly   340 IAALHWIKENIEAFGGDNSRVTLMGHSTGAACVNYL----MVSPVASGLFHRAILMSGSAM---S 397
            |.||.::...|..||||..:||:||||:|...|..|    ||.|... ||.:.|::|.:.|   .
 Worm   179 ILALDFVHNEISNFGGDPEKVTIMGHSSGGTLVEALGFSSMVDPELK-LFQQMIMLSSTGMFGFD 242

  Fly   398 DWAASNQSLQLTMQIAHALECPLNEHVEAEDDDV--LLDCLRHRRYQDILHIP---TALTQFSTS 457
            |....|     :..|...|.|......|....:|  .|||:||....:||.:.   ..:.|.|..
 Worm   243 DLVIDN-----SFTIVEKLGCFNGTKEERNTVNVAETLDCMRHIDGYEILRVQQKMELMDQLSFK 302

  Fly   458 LGPIVDGHVIPNQPYKVM-GHYTE---HFSRYDLLFGITESESYHTLAALALEEGLRENERDNLL 518
                   :::...|:.:: |:..:   :.|..:.:||.||.|.
 Worm   303 -------YLLRGAPFMLLNGNIADLKKNTSPRNAIFGTTEHEF---------------------- 338

  Fly   519 RFYMQSRFDIRPD-LALAATLKKYQDMYNNPIK-ATNLEHR-----------DVVLDILSDARVV 570
                   ||:... |.:..|...|:    ||:. |.|.:.|           |.....:|.|...
 Worm   339 -------FDVTEKYLYITVTFLDYE----NPVAVARNYDGRLMKNMETMITGDSAAIFVSTATCA 392

  Fly   571 GPLLQTGMFHADV----NRRNYMYVFGHNSATGPFAHLPHSIMGEELAFIFGAPLAAAGPFPSGN 631
            ..:...|   |||    .|::|                  |:...::.:..|...|       .|
 Worm   393 AAMANAG---ADVFLFETRQSY------------------SVHVSDMQYFIGNHCA-------HN 429

  Fly   632 YTVQEKLLSEAVMAYWTNFVKTGNPKAPWKGIFINSHALEWDRYDLDWPEFNRRAQAYLNIGIPP 696
            .|:...:|........|||.|.|.|...|..:         |...:::.|....::|  ..|...
 Worm   430 RTIDIDILDSFYSKLLTNFTKHGKPSPGWDPV---------DPGRMNYLELKVDSKA--RSGPVM 483

  Fly   697 TVGYKYRQIYMNFWNKELPDELNQIAAIQEQLQKPGQEVITGHMSKY 743
            ..||..:.:  :||..|:.:....::.::.....|.:...|....:|
 Worm   484 LEGYHAKDV--SFWVGEMTEFDQNVSKMRHSEGLPPERQDTKSQRQY 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_001246966.1	COesterase	153..710	CDD:278561	139/595 (23%)
		Aes	<263..>408	CDD:223730	49/154 (32%)
cest-8	NP_001359583.1	Abhydrolase	19..495	CDD:389770	138/592 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810