Protein Alignment Nlg1 and ace-1

DIOPT Version :9

• Sequence 1: NP_001246966.1
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_510660.1
• Gene: ace-1 / 181706
• WormBaseID: WBGene00000035
• Length: 620
• Species: Caenorhabditis elegans
• Alignment Length: 668
• Identity: 191/668 - (28%)
• Similarity: 291/668 - (43%)
• Gaps: 135/668 - (20%)

  Fly   136 PSTTHHPERRHVVPDKLQYTQEIQVKQGRLMGITRRFQVTSGLRQVDQFLGLPYAEAPTGNRRFM 200
            |||....:..|:......:.:|:..:.|:  .:||             |.|:|:||.|.||.||.
 Worm    12 PSTILAVDLIHLHDGSPLFGEEVLSQTGK--PLTR-------------FQGIPFAEPPVGNLRFK 61

  Fly   201 PPGAPLPWQGLKIARHLPPVCPQK----LPDLSPHGSENMSRARHKHLSRLLPYLRTESEDCLYL 261
            .|....||:....|...|..|.|.    ..|.  :|| .|..|..|           .|||||||
 Worm    62 KPKPKQPWRIPLNATTPPNSCIQSEDTYFGDF--YGS-TMWNANTK-----------LSEDCLYL 112

  Fly   262 NLYVPHE-EPQSTPKQYAVLVYLHGESFEWNSG----NPYDGSVLSSYGEVIVVTVNYRLGVLGF 321
            |:|||.: :|.   |:.||:|:::|..| | ||    :.|||.:|:....||:|.:|||:.:.||
 Worm   113 NVYVPGKVDPN---KKLAVMVWVYGGGF-W-SGTATLDVYDGRILTVEENVILVAMNYRVSIFGF 172

  Fly   322 L---RPSIDAHNIANYALLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASG 383
            |   ||...    .|..:.||:.|:.|:.:||:.||||.||:||.|.|.|||.|:..|:||.::.
 Worm   173 LYMNRPEAP----GNMGMWDQLLAMKWVHKNIDLFGGDLSRITLFGESAGAASVSIHMLSPKSAP 233

  Fly   384 LFHRAILMSGSAMSDWAASNQSLQLTMQIA--HALECPLNEHVEAEDDDVLLDCLRH-------- 438
            .|||||:.||||.|.||...:.:.|...:.  :|::|. |..:...|.|.:|||.:.
 Worm   234 YFHRAIIQSGSATSPWAIEPRDVALARAVILYNAMKCG-NMSLINPDYDRILDCFQRADADALRE 297

  Fly   439 ------RRYQDILHIPTALTQFSTSLGPIVDGHVIPNQPYKVMGHYTEHFSRYDLLFGITESESY 497
                  |.:.|...:            |:|||..:.......:..  .:|.:..||.|....||.
 Worm   298 NEWAPVREFGDFPWV------------PVVDGDFLLENAQTSLKQ--GNFKKTQLLAGSNRDESI 348

  Fly   498 HTLA-----ALALEEGLRENERDNLLRFYMQSRFDIRP------DLALAATLKKY--QDMYNNPI 549
            :.|.     ...:.:...:.:.....:.:::...|:.|      .|.|||.|.:|  ||:...|
 Worm   349 YFLTYQLPDIFPVADFFTKTDFIKDRQLWIKGVKDLLPRQILKCQLTLAAVLHEYEPQDLPVTP- 412

  Fly   550 KATNLEHRDVV--LD-ILSDARVVGPLLQTGMFHADVNRRNYMYVFGHNSATGPFAHLPHSIMGE 611
                   ||.:  :| :|.|......:.:..:.|.......|.|.|.|.::...:......:.|.
 Worm   413 -------RDWINAMDKMLGDYHFTCSVNEMALAHTKHGGDTYYYYFTHRASQQTWPEWMGVLHGY 470

  Fly   612 ELAFIFGAPLAAAGPFPSGNYTVQEKLLSEAVMAYWTNFVKTGNPKAPWKGIFINSHALEWDRYD 676
            |:.||||.||..    ...|||.:|:.||...|.||.||.|||:|.....|.|..         |
 Worm   471 EINFIFGEPLNQ----KRFNYTDEERELSNRFMRYWANFAKTGDPNKNEDGSFTQ---------D 522

  Fly   677 LDWPEFNRRAQAYLNIGIPPT------VGYKYRQIYMNFWNKELPDELNQIAAI-------QEQL 728
            : ||::|..:..|:|:.:..:      :|:..|:....||...||:.:..:|.:       ::|:
 Worm   523 V-WPKYNSVSMEYMNMTVESSYPSMKRIGHGPRRKECAFWKAYLPNLMAAVADVGDPYLVWKQQM 586

  Fly   729 QKPGQEVITG---HMSKY 743
            .|...|.||.   |..:|
 Worm   587 DKWQNEYITDWQYHFEQY 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_001246966.1	COesterase	153..710	CDD:278561	175/606 (29%)
		Aes	<263..>408	CDD:223730	64/152 (42%)
ace-1	NP_510660.1	COesterase	13..561	CDD:278561	178/622 (29%)
		Aes	<114..>249	CDD:223730	62/143 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910