Protein Alignment Nlg1 and cest-3

DIOPT Version :9

• Sequence 1: NP_001246966.1
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_510042.2
• Gene: cest-3 / 181385
• WormBaseID: WBGene00008451
• Length: 588
• Species: Caenorhabditis elegans
• Alignment Length: 695
• Identity: 145/695 - (20%)
• Similarity: 249/695 - (35%)
• Gaps: 215/695 - (30%)

  Fly   127 TDEGSSEHEPSTTHHPERRHVVPDKLQYTQEIQVKQGRLMGITRRFQVTSGLRQVDQ--FLGLPY 189
            |..||.:...|||:                      |:|.|.|         ..|||  |..:|:
 Worm    15 TLNGSGQRIISTTY----------------------GKLEGKT---------VNVDQHMFKNVPF 48

  Fly   190 AEAPTGNRRFMPPGAPLPWQGLKIARHLPPVCPQKLPDLSPHGSENMSRARHKHLSRLLPYLRTE 254
            |:.|.|..||..|....||:.::.|....|.|              .|.:..:..|...|.
 Worm    49 AKPPLGKLRFSLPEWTNPWKNIRNATEYSPSC--------------FSNSSMRTDSNFFPM---- 95

  Fly   255 SEDCLYLNLYVPHEEPQSTPKQYAVLVYLHGESFEWNSGNPY-DGSVLSSY--GEVIVVTVNYRL 316
            ||||||||::.  .|.....|..:.:||.||.....:|...: |..:|..|  ..|:.:...|||
 Worm    96 SEDCLYLNVFT--NEYCLKSKNCSTVVYYHGGGINMDSAVQFNDTFILERYVKENVVFIIPAYRL 158

  Fly   317 GVLGFLRPSIDAHNIA--NYALLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGA---------- 369
            |:.|.|  ...::|:.  |.|:.|...||.:|.:.|..|||....:.|||||.||
 Worm   159 GIFGLL--YFGSNNLVPQNLAIHDCELALRFIHQEISNFGGHKDDINLMGHSAGAHISLIFGFSR 221

  Fly   370 ------ACVNYLMV-SPVASGLFHRAILMSGSAMSDWAASNQSLQLTMQIAHALECPLNEHVEAE 427
                  ..:|.::| |||.|           ..|.:....|     ....|..:.| ...:|.|.
 Worm   222 HIDPDHKLINRIIVLSPVPS-----------YDMPELLIKN-----CYDFAERVGC-YKRNVTAR 269

  Fly   428 DDDVLLDCLRHRRYQDILHIPTALTQFSTSLGPIVDG------HVIPNQPY----KVMGHYTEHF 482
            |.:: :.|||.:..:.::           |:..:::.      :.:..:|:    :.:..:.|:.
 Worm   270 DTEI-VKCLRKKDARGLM-----------SMQRLMENDRLYFWNFLAGEPFMYRDESIADFKEYA 322

  Fly   483 SRYDLLFGITESESYHTLAALALEEGLRENERDNLLRFYMQSRFDIRPDLALAATLKKYQDMYNN 547
            .:.|:|.|.|..|       :..:...:||.                   |:|.:...:::.|..
 Worm   323 VKRDMLIGNTVDE-------VKWKRLKKENP-------------------AIAGSFMDWENPYEV 361

  Fly   548 PIKATNLEHRDVVLDILSDARVVGPLLQTGMF-HADVNRRNYMYVFGHNSATGPFAHLPHSIMGE 611
            ..| .|..|....::...::...|..:.|..: .|..|....:|:|..|..  |.:|:      .
 Worm   362 AHK-FNFYHDSAPVNSTYESFTQGIFVSTATYAEAQANAGGTVYLFQSNQQ--PSSHV------S 417

  Fly   612 ELAFIFGAPLAAAGPFPSGNYTVQEKLLSEAVMAYWTNFVKTGNPKAPWKGIF---INSHALE-- 671
            ::.:..|   .....:.:.:..:.:...|:.::    ||.|.|:|...|:.:.   :|.:|||
 Worm   418 DMQYFVG---THREDYHTSDMDIMDTFYSKMIV----NFTKFGSPSPVWEPLVPSRMNYYALEVN 475

  Fly   672 -----WDRYDLDWPEFNRRAQAYLNIGIPPTVGYKYRQIYMNFWNKELPDELNQIAAIQEQLQKP 731
                 |.|.:.|:.|.:                       :|||      .:|..|..:|..::
 Worm   476 TEKGIWPRMEEDFHESD-----------------------VNFW------FINMTAFDREVTRQ- 510

  Fly   732 GQEVITGHMSKYGPRDHGAEDPVRTLKLLLQEPSLAGPTQSGEST 776
             ::...|....:.|...|   ||     :|       ||::.||:
 Worm   511 -KKTSNGTSLTWSPMHPG---PV-----IL-------PTKTNESS 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_001246966.1	COesterase	153..710	CDD:278561	124/601 (21%)
		Aes	<263..>408	CDD:223730	43/166 (26%)
cest-3	NP_510042.2	Abhydrolase	23..496	CDD:304388	127/619 (21%)
		Aes	<118..>254	CDD:223730	41/153 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810