Protein Alignment Nlg1 and cest-26

DIOPT Version :10

• Sequence 1: NP_731172.2
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_001368609.1
• Gene: cest-26 / 180715
• WormBaseID: WBGene00017478
• Length: 585
• Species: Caenorhabditis elegans
• Alignment Length: 622
• Identity: 159/622 - (25%)
• Similarity: 257/622 - (41%)
• Gaps: 119/622 - (19%)

  Fly   137 STTHHPERRHVVPDKLQYTQEIQVKQGRLMGITRRFQVTSGLRQVDQFLGLPYAEAPTGNRRFMP 201
            |..||.| .::.|.|     :::.:.|.:.|.  |.::... |:||.|||:|:|:||.|:.||..
 Worm    29 SLRHHNE-SNLTPSK-----QVRTRNGLVEGF--RIKIDDD-REVDMFLGIPFAKAPVGDLRFKN 84

  Fly   202 PGAPLPWQGLKIARHLPPVCPQKLPDLSPHGSENMSRARHKHLSRLLPYLRTESEDCLYLNLYVP 266
            |.....|.|:|......|..||     :....|..:....|            ||||||||::.|
 Worm    85 PEHTEDWDGVKKCVRFGPRAPQ-----ADFFWERFTLGVGK------------SEDCLYLNVFSP 132

  Fly   267 HEEPQSTPK-QYAVLVYLHGESFEWNSGNPYDGSVLSSY---GEVIVVTVNYRLGVLGFLRPSID 327
            ..:.:.... .:.|:||:||..|..:|...|....::.|   ..|:|||:.||||:|||.... |
 Worm   133 TWKAEEVSNGLHPVMVYVHGGGFLIDSAVKYGDEGIAKYLCRHGVVVVTIQYRLGLLGFFSTG-D 196

  Fly   328 AHNIANYALLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASGLFHRAILMS 392
            .....|..|.|...||.|:::|:.|||||..:||:.|.|.|...|:.|.:||.:..|||:.:.|:
 Worm   197 QVCPGNLGLWDMTMALQWVRDNVHAFGGDPRKVTVFGQSAGGVSVDLLSLSPHSRDLFHQVVPMA 261

  Fly   393 GSAMSDWA--ASNQSLQLTMQIAHALECPLNEHVEAEDDDV---LLDCLRHRRYQD-----ILHI 447
            |:...:|:  ..|:.:....:.|:. :|  .:..:|.|::.   :|:.||.|:.::     :...
 Worm   262 GNGECEWSTVGKNRLVNACREFAYR-KC--WDEKQARDENASESMLEFLRTRKEREFEKRLLTRK 323

  Fly   448 PTALTQFSTSLGPIVDGHVIPNQPYKVMGHYTEHFSRYDLLFGITESESY--------------- 497
            ...:::....|.|::........| |.:....:...:.:::.|..|.|..
 Worm   324 GVDVSKIGLDLAPVIGSKPSDFLP-KSIEELRKEAPKKNIMVGTCEHEGLLFASLGPSNFDEKGI 387

  Fly   498 -HTLAALALEEGLRENE--RDNLLRFYMQSRFDIRPDLALAAT--LKKYQDM------YNNPIKA 551
             ..||.|..||...:.|  |:...:.|::...|...|..:||.  ::.|.|:      ||...|.
 Worm   388 DKLLALLITEENHEDFEALREEAKKMYLKKLSDDEDDKEVAARGYIQLYSDLFVNNGTYNYAEKM 452

  Fly   552 TNLEHRDVVLDILSDARVVGPLLQTGMFHAD-VNRRNYMYVFGHNSATGPFAHLPHSIMGEELAF 615
            |.|.::                  ..|:..| .|.|:    ||..|...||....|.   .|||:
 Worm   453 TKLGNK------------------VFMYSFDYCNPRS----FGILSLRAPFRAATHC---TELAY 492

  Fly   616 IFGAPLAAAGPFPSGNYTVQEKLLSEAVMAYWTNFVKTGNPKAPWKGIFINSHALEWDRYDLDW- 679
            |||..:..     :..|...::.:.:.:...||||.|.|||...::...:         :|..|
 Worm   493 IFGVSIVF-----NYRYNESDRAMLDLMTKMWTNFAKYGNPNGQYEDSTV---------FDFKWE 543

  Fly   680 PEFNRRAQAYLNIGIP----PTVGYKYRQIYMNFWNK 712
            |........:|.|...    .||   |:.....||.|
 Worm   544 PTSKEEPTNFLAINEKKCEMQTV---YQDNRAEFWKK 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_731172.2	COesterase	157..710	CDD:395084	150/598 (25%)
cest-26	NP_001368609.1	COesterase	40..575	CDD:395084	152/606 (25%)