Protein Alignment Nlg1 and cest-34

DIOPT Version :9

• Sequence 1: NP_001246966.1
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_001360105.1
• Gene: cest-34 / 179057
• WormBaseID: WBGene00019652
• Length: 550
• Species: Caenorhabditis elegans
• Alignment Length: 602
• Identity: 154/602 - (25%)
• Similarity: 238/602 - (39%)
• Gaps: 168/602 - (27%)

  Fly   177 GLRQVDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLPPVCPQKLPDLSPHGSENMSRARH 241
            |.::|..:||:|||:.|||..||..|.....|...:......|.||       |.| :.:.:..
 Worm    32 GDKEVHGYLGMPYAKPPTGEMRFAKPVPADDWTETRDCTKYGPRCP-------PSG-QGLEKGM- 87

  Fly   242 KHLSRLLPYLRTESED---CLYLNLYVPHEEPQSTPKQYAVLVYLHGESFEWNSGNPY-DGSVLS 302
                    ::..:..|   .|.:|::||..|.........|:||:||..||.:|...: |.|:.|
 Worm    88 --------FVNPDEPDEANGLSVNVFVPGWESSEYKNARPVMVYVHGGGFEISSSREFCDYSISS 144

  Fly   303 S--YGEVIVVTVNYRLGVLGFLRPSIDAHNIANYALLDQIAALHWIKENIEAFGGDNSRVTLMGH 365
            :  ..:||:||:|||||:|||.... |.....|:.|.||..||.|::::|.:||||.:.|||.|.
 Worm   145 TLPMKDVILVTMNYRLGILGFFTTG-DEVCPGNFGLWDQTLALQWVQKHIASFGGDPNNVTLFGQ 208

  Fly   366 STGAACVNYLMVSPVASGLFHRAILMSGSAMSDWA---ASNQSLQLTMQIAHALECPLNEHVEAE 427
            |.|.|||:.|.:||.:..||.:.:.||||||.::|   |.|:        ||..
 Worm   209 SAGGACVDLLTLSPHSRDLFQKVVPMSGSAMCEFAMRTAENE--------AHVF----------- 254

  Fly   428 DDDVL-------------LDCLRHRRYQDILHIPTALTQFS------TSLGPIVDGHVIPNQPYK 473
             ||:|             |:.:|......|    |..|.::      .||.|..||...|    |
 Worm   255 -DDILARLGFTGSGSKERLEFMRSLPCDKI----TGKTGYTYKQSGFMSLCPNYDGDFFP----K 310

  Fly   474 VMGHYTEHFSRYDLLFGITESE-------------SYHTLAALALEEGLRENE-------RDNLL 518
            .:....:..|:..|:.||..:|             .|..|..|.:||..:|:.       |..:.
 Worm   311 PLDELRKDASKRILMTGIVGNEGLLFAFDRNTPYKDYTDLLRLKIEEDYKEDVVDDVEGIRKEIF 375

  Fly   519 RFYMQ--SRFDIRPDLALAATLKKYQDMYNNPIKAT---NLEHRDVVLDILSDARVVGPLLQTGM 578
            .:|.:  |..|....:..||.... ..:::..::||   ..||.|.|
 Worm   376 EYYTKNISEGDEEAIMRKAAEFVG-DSIFHTGVRATAQNAAEHGDEV------------------ 421

  Fly   579 FHADVNRRNYMYVFGHNSATGPFA----HLPH--SIMGEELAFIFGAPLAAAGPFPSGNYTVQEK 637
                     ::|.|.:.:..| ||    :||:  ...|.||.::||     .|.......|.:|.
 Worm   422 ---------WLYNFDYCNPDG-FAPLKGYLPYIEPTHGMELRYLFG-----DGIISKFEPTEEEL 471

  Fly   638 LLSEAVMAYWTNFVKTGNPKAPWKGIFINSHALEWDRYDLDWPEFNRRAQAYLNIGIPPTVGYKY 702
            .:.:.....:.||.|.|||.        .:.:..|:::|                  |...|..|
 Worm   472 KMLDKFTTMFANFAKYGNPN--------ETGSSAWEKFD------------------PARPGRHY 510

  Fly   703 RQIYMNFWNKELPDELN 719
            |   :::.|..:.||.:
 Worm   511 R---ISYPNSGMEDEFS 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_001246966.1	COesterase	153..710	CDD:278561	151/591 (26%)
		Aes	<263..>408	CDD:223730	62/150 (41%)
cest-34	NP_001360105.1	COesterase	15..530	CDD:365897	154/602 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810