Protein Alignment Nlg1 and cest-35.1

DIOPT Version :10

• Sequence 1: NP_731172.2
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_504400.1
• Gene: cest-35.1 / 178912
• WormBaseID: WBGene00015067
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 619
• Identity: 153/619 - (24%)
• Similarity: 242/619 - (39%)
• Gaps: 173/619 - (27%)

  Fly   181 VDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLPPVCPQK-------LPDLSPHGSENMSR 238
            ||.:||:|:|:||.|..||........|..........|.|||.       :|..|.
 Worm    36 VDGYLGIPFAKAPIGELRFKKSVEAEKWTEPLDCYKYGPGCPQSGALGAMIVPQASA-------- 92

  Fly   239 ARHKHLSRLLPYLRTESED-CLYLNLYVPHEEPQSTPKQYAVLVYLHGESFEWNSGNPYDGSVLS 302
                        :|..:|| ||.||::.|..:....|....|:||.:|..||....:.:|...|:
 Worm    93 ------------IREFAEDNCLTLNVFAPKWKSAEFPNGLPVIVYFYGGGFEVGFSSMFDDYSLT 145

  Fly   303 S---YGEVIVVTVNYRLGVLGFLRPSIDAHNIANYALLDQIAALHWIKENIEAFGGDNSRVTLMG 364
            .   ..:||:||.|||:|.|||.....|... .|:.|.||..||.|::::|::||||.|.||:.|
 Worm   146 GTLPLKDVILVTPNYRIGPLGFFATGDDVSR-GNWGLWDQALALQWVQKHIKSFGGDPSNVTISG 209

  Fly   365 HSTGAACVNYLMVSPVASGLFHRAILMSGSAMSDWAASNQSLQLTMQIAHALECPLNEHVEAEDD 429
            .|.|.|.|::|.:||.|:..||:.|.|||:|                     .||..  :.::|.
 Worm   210 TSAGGASVDFLSLSPHANKYFHKFIPMSGAA---------------------TCPFG--IRSKDV 251

  Fly   430 DVLL--DCLRHRRY-----QDILH-----------------IPTALTQFSTSLGPIVDGHVIPNQ 470
            :.|:  :..:|..|     :.:||                 .| |...|  |..|..||...|
 Worm   252 EGLIFREFAKHHGYAGNDSESLLHWYQSQDAEIFLKAEGFKYP-ASGMF--SFVPNYDGDFFP-- 311

  Fly   471 PYKVMGHYTEHFSRYDLLFGITESESYHTLAALALEEGLRENERDNLLRFYMQSRFDIRPDLALA 535
              |......:...:.|.:..:.|.|      .|..||            ||...:   .|...|.
 Worm   312 --KPFDELRKEAPKLDAIVSVAEYE------GLGFEE------------FYPGQK---SPQEVLT 353

  Fly   536 ATL-----KKYQDMYNNPIKA--TNLEHRD------VVLDILSD----ARVVGPLLQTGMFHADV 583
            |.|     :..:::....::|  .|:|.:.      .:::|..|    ..|...:.....:..:|
 Worm   354 AALGPEVVRNREEVVKKAVEAYLENIEDKSGEKIGKKLVEIFGDYYFSVGVFDTVRSLAKYGNNV 418

  Fly   584 NRRNYMY-------VFGHNSATGPFAHLPHSIMGEELAFIFGAPLAAAGPFPSGNYTVQEKLLSE 641
            ...::.|       :||.|.   ||....|   |.::.:|.|..:        |.::.:::.:.:
 Worm   419 YLSSFNYFNPETPIMFGENR---PFNAASH---GCDIRYILGDGI--------GEFSKEDRKVMD 469

  Fly   642 AVMAYWTNFVKTGNPKAPWKGIFINSHALEWDRYDLDWPEFNRRAQAYLNIGIPPTVGYKYRQIY 706
            .:..|.|||.|.|||..  ||:     ::.|::|.||.|      ..|..|..|..      ::.
 Worm   470 MMGTYLTNFAKYGNPNG--KGV-----SIPWEKYSLDNP------GRYFKIDYPKC------EMA 515

  Fly   707 MNFWN--KELPDELNQIAAIQEQLQKPGQEVITG 738
            .||.:  .::.||:|: ..||.      ||::.|
 Worm   516 DNFLDGRYKIIDEVNE-HGIQY------QEMVFG 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_731172.2	COesterase	157..710	CDD:395084	144/587 (25%)
cest-35.1	NP_504400.1	COesterase	16..523	CDD:395084	145/591 (25%)