Protein Alignment Nlg1 and cest-35.2

DIOPT Version :10

• Sequence 1: NP_731172.2
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_504398.1
• Gene: cest-35.2 / 178910
• WormBaseID: WBGene00016863
• Length: 544
• Species: Caenorhabditis elegans
• Alignment Length: 661
• Identity: 163/661 - (24%)
• Similarity: 258/661 - (39%)
• Gaps: 194/661 - (29%)

  Fly   146 HVVPDKLQYTQEIQVKQGRLMGITRRFQVTSGLRQVDQFLGLPYAEAPTGNRRFMPPGAPLPW-Q 209
            |:.|:|  .|:......|.:.|..    ...|.:.|:.:||:|:|:||.|:.||........| |
 Worm     7 HLKPEK--NTEVFNASCGPIRGNV----YEHGDKIVNGYLGIPFAKAPIGDLRFKKSVEAEKWTQ 65

  Fly   210 GLKIARHLPPVCPQKLPDLSPHGSENMSRARHKHLSRLLPYLRTESEDCLYLNLYVPHEEPQSTP 274
            .|...:: .|.|||.    :..|:..:|:|.:...:         .::||.||::.|..:....|
 Worm    66 PLDCYKY-GPGCPQS----AALGALMVSQATNHDFA---------EDNCLNLNVFAPKWKSAEFP 116

  Fly   275 KQYAVLVYLHGESFEWNSGNPYDGSVLSS---YGEVIVVTVNYRLGVLGFLRPSIDAHNIANYAL 336
            ..:.|:||.:|..||....:.:|...|:.   ..:||:||.|||:|.|||.....|... .|:.|
 Worm   117 NGFPVMVYFYGGGFEVGFSSMFDDYSLTGTLPLKDVILVTPNYRIGPLGFFATGDDVAR-GNWGL 180

  Fly   337 LDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASGLFHRAILMSGSA------ 395
            .||..||.|::::|::||||.|.||:.|.|.|.|.|::|.:||.|:..|.:.|.|||:|
 Worm   181 WDQALALQWVQKHIKSFGGDPSNVTISGTSAGGASVDFLSLSPHANKYFQKFIPMSGAATCPFGI 245

  Fly   396 --------------------------MSDWAASNQSLQLTMQIAHALECPLN---EHVEAEDDDV 431
                                      :..|..|..| ::.:: |...:||.:   ..|...|.|.
 Worm   246 RSKDVEGLIFREFANHHGYTGNDSKSLLQWYQSQDS-EIFLK-AEGYKCPASGMFSFVPNFDGDF 308

  Fly   432 L---LDCLRHR--RYQDILHI---------------PTALTQFSTSLGPIVDGHVIPNQPYKVMG 476
            .   .|.||..  :...|:.|               .|.....|.:|||    .|:.|:...|.
 Worm   309 FPKPFDELRKEAPKLGAIVSIGEYEGLGFEDFYAGQKTPQQMLSAALGP----EVVRNREEVVK- 368

  Fly   477 HYTEHFSRYDLLFGITESESYHTLAALALEEGLRENERDNLLR---------FYMQSRFD-IRPD 531
                           ..:|||       |:.|..||| :|:.:         ::....|| :|..
 Worm   369 ---------------RAAESY-------LKNGGNENE-ENIAKTLVEIFGDYYFSVGAFDTVRSL 410

  Fly   532 LALAATLKKYQDMYNNPIKATNLEHRDVVLDILSDARVVGPLLQTGMFHADVNRRNYMYVFGHNS 596
            :....|:..|...|.||                                      |...|||.|.
 Worm   411 VKYGNTVYLYSFNYFNP--------------------------------------NTPIVFGKNR 437

  Fly   597 ATGPFAHLPHSIMGEELAFIFGAPLAAAGPFPSGNYTVQEKLLSEAVMAYWTNFVKTGNPKAPWK 661
               ||....|   |.:|.:|||.        .:|.::.:::.:.:.:..|.|||.|.|||..  |
 Worm   438 ---PFNAANH---GSDLRYIFGE--------GTGEFSKEDRQVMDMMGTYHTNFAKYGNPNG--K 486

  Fly   662 GIFINSHALEWDRYDLDWPEFNRRAQAYLNIGIPPTVGYKYRQIYMNFWN--KELPDELNQIAAI 724
            |:     ::.|::|.||.|      ..|..|..|..      ::..||.:  .::.||:|: ..|
 Worm   487 GV-----SVPWEKYSLDNP------GRYFKIDYPKC------EMADNFLDGRHKIIDEVNE-HGI 533

  Fly   725 QEQLQKPGQEV 735
            |.|....|:::
 Worm   534 QYQEMVFGKKI 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_731172.2	COesterase	157..710	CDD:395084	151/621 (24%)
cest-35.2	NP_504398.1	COesterase	18..517	CDD:395084	150/618 (24%)