Protein Alignment Nlg1 and cest-32

DIOPT Version :9

• Sequence 1: NP_001246966.1
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_504397.1
• Gene: cest-32 / 178909
• WormBaseID: WBGene00016862
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 595
• Identity: 161/595 - (27%)
• Similarity: 251/595 - (42%)
• Gaps: 125/595 - (21%)

  Fly   181 VDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLPPVCPQKLPDLSPHGSENMSRARHKHLS 245
            |:.:||:|:|:||....||..|.....|..........|.|||     |.|           .:|
 Worm    36 VNGYLGIPFAKAPICELRFKKPVEAEKWTKPLNCHKYGPGCPQ-----SGH-----------MIS 84

  Fly   246 RLLP--YLRTESEDCLYLNLYVPHEEPQSTPKQYAVLVYLHGESFEWNSGNPYDGSVLSS---YG 305
            .|||  |.....::||.||::.|..:.:..|....::||.||..||....:.:|...||.   ..
 Worm    85 NLLPPGYREFAEDNCLNLNIFAPSWKSEEFPNGLPIMVYFHGGGFEIGFSSMFDDYSLSGTLPLK 149

  Fly   306 EVIVVTVNYRLGVLGFLRPSIDAHNIANYALLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAA 370
            :|||||.|||:|.|||:... |..:..||.|.||..||.|::|:|::|||:.:.||:.|.|.|..
 Worm   150 DVIVVTANYRVGPLGFMTTG-DEVSRGNYGLWDQTLALKWVQEHIKSFGGNPNIVTVCGTSAGGV 213

  Fly   371 CVNYLMVSPVASGLFHRAILMSGSAMSDWAASNQSLQLTMQIAHALECPLNEH-VEAEDDDVLLD 434
            ....|.:||.::.||||.:.|||||..::     |::...|.|.........| .|.||.:.||:
 Worm   214 SAGLLALSPHSNKLFHRFMAMSGSAFCEF-----SIRTKEQEAEIFRNFAKHHGYEGEDSESLLE 273

  Fly   435 CLRHR---RYQDILHIPTALTQFSTSLGPIVDGHVIPNQPYKVMGHYTEHFSRYDLLFGITESES 496
            ..:.:   ::|:........:.|.|.: |..||...| :|:       :..||        |:..
 Worm   274 WYKSQPLSKFQETATFEKKASGFLTFI-PNFDGDFFP-KPF-------DELSR--------EAPK 321

  Fly   497 YHTLAALALEEGL--------RENERDNLLRFY----MQSRFDIRPDLALAATLKKYQDMY---- 545
            ...:|.:...|||        |.|:.|.:...:    :::..|::         |:..:.|
 Worm   322 LDAMATVDEYEGLGFLTMFQSRRNDMDIIKSSFGSDVVENAVDVQ---------KRIMEFYMKNI 377

  Fly   546 -NNPIKATNLEHRDVVLDILSDARVVGPLLQTGMFHADVNRRNYM-----YVFGHNS--ATG-PF 601
             .|..||  :|.|  ::.::||:......|:|...........|:     |..|.|.  ||. ||
 Worm   378 DKNDDKA--VEKR--LIQLISDSWFNIGALETVKTSTKYGSNAYLGSFDYYNMGSNDPYATWFPF 438

  Fly   602 AHLPHSIMGEELAFIFGAPLAAAGPFPSGNYTVQEKLLSEAVMAYWT-NFVKTGNPKAPWKGIFI 665
            ....|   |.||.::.|..:....|       ::|:.....:|...| ||||.|||..      |
 Worm   439 KAANH---GSELKYMLGEGMGKFSP-------IEEEFKVIDMMGTLTANFVKYGNPNG------I 487

  Fly   666 NSHALEWDRYDLDWPEFNRRAQAYLNIGIPPTVGYKYRQIYMNFWNKELP--DELNQIAAIQEQL 728
            |...| |.:|.   ||   :..:|..|..|.:      ::..||.:..|.  :::|:.:
 Worm   488 NGPEL-WKKYT---PE---KPYSYFKIDYPKS------EMRDNFQDGRLKLFEDINKSS------ 533

  Fly   729 QKPGQEVITG 738
             |..||::.|
 Worm   534 -KKFQEIVYG 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_001246966.1	COesterase	153..710	CDD:278561	154/563 (27%)
		Aes	<263..>408	CDD:223730	55/147 (37%)
cest-32	NP_504397.1	COesterase	15..516	CDD:278561	153/560 (27%)
		Aes	<104..>227	CDD:223730	45/123 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810