Protein Alignment Nlg1 and ges-1

DIOPT Version :9

• Sequence 1: NP_001246966.1
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_503411.1
• Gene: ges-1 / 178633
• WormBaseID: WBGene00001578
• Length: 562
• Species: Caenorhabditis elegans
• Alignment Length: 636
• Identity: 151/636 - (23%)
• Similarity: 246/636 - (38%)
• Gaps: 188/636 - (29%)

  Fly   158 IQVKQGRLMGITRRFQVTSGLRQVDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLPPVCP 222
            ::...|::.||.        ....:.||.:|:|:.|..:.||..|.||.||:.:..|       .
 Worm    20 VETNYGKVEGIE--------YEGAEVFLAIPFAKPPVDDLRFEKPVAPDPWEDVYPA-------T 69

  Fly   223 QKLPDLSPHGSENMSRARHKHLSRLLPYLRTESEDCLYLNLYVPHEEPQSTPKQYAVLVYLHGES 287
            |...|.:||         ::.:::...|   ..||||.||:..| ::.:..|    ||.::||..
 Worm    70 QYRNDCTPH---------YRLVAQFSSY---SGEDCLTLNIIKP-KKAEKLP----VLFWIHGGG 117

  Fly   288 FEWNS----GNPYDGSVLSSYGEVIVVTVNYRLGVLGFL-RPSIDAHNIANYALLDQIAALHWIK 347
            :|..|    |..:.....:|.| |||.||.||||.:||. ..:.|..  .|:.|.||.|||.::|
 Worm   118 YEIGSASQHGYEFFAKRYASQG-VIVATVQYRLGFMGFFSEGTSDVQ--GNWGLFDQAAALEFVK 179

  Fly   348 ENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASGLFHRAILMSGSAMSDWAASNQSLQLTMQI 412
            .|||.||||.:::|:.|:|.|||.|:.|.:||.....:.:||:||.|:...||.....::.:.|:
 Worm   180 SNIENFGGDPNQITIWGYSAGAASVSQLTMSPYTRDSYSKAIIMSASSFVGWATGPNVVETSKQL 244

  Fly   413 AHALECP---LNEHVEAEDDDVLLDCLRHRRYQ----DILHIPTALTQFSTSLGPIVDGHVIPNQ 470
            |..|.||   ..|.::.:....:.|.:..:.:.    |||.           ..|::||..:...
 Worm   245 AEILGCPWPGAKECMKKKSLHEIFDAIEVQGWTTGTIDILR-----------WSPVIDGDFMTKN 298

  Fly   471 PYKVMGHYTEHFSRYDLLFGITESESYHTLAALALEEGL-------------------------- 509
            |.::                |.||....||..::.:||.
 Worm   299 PEEL----------------IKESPVKPTLIGMSNKEGSYFAALNMGRVIADFGLSPEDMPKVDE 347

  Fly   510 --------------------RENERDNLLRFYMQSRFDIRPDLALAATLKK----YQDMYNNPIK 550
                                ||...:::|.||::..   :|     |.:|.    |.|.|:
 Worm   348 EFISEIIGRKLLYNNRYGENREKVWNDILDFYVKQG---KP-----AEVKDLNGFYVDRYS---- 400

  Fly   551 ATNLEHRDVVLDILSDARVVGPLLQTGMFHADVNRRN--YMYVFGHNSATGPFAHLPHSIMG--- 610
                       ::|||.....|:|:.  ..:.|.|:.  :.|...|........|:|....|
 Worm   401 -----------ELLSDITFNVPILRE--ITSRVERKTPVWTYRMDHYDKNIWKKHIPEQARGSPH 452

  Fly   611 -EELAFIFGAP-LAAAGPFPSGNYTVQEKLLSEAVMAYWTNFVKTGNPKAPWKGIFINSHALEWD 673
             .|..::|..| :|........:..:|..|:...:     :|.|||.|:..
 Worm   453 ANEYHYLFDMPVMAKIDMKKEPDSWIQNDLIDMVI-----SFAKTGVPQIE-------------- 498

  Fly   674 RYDLDW-PEFNRRAQAYLNI---GIPPTVGYKYRQIYMNFWNKELPDELNQ 720
              |::| |..:.....:|||   |:  ::.:...|..:.|||     ||.|
 Worm   499 --DVEWRPVSDPDDVNFLNIRSDGV--SIEHGLFQEPLAFWN-----ELRQ 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_001246966.1	COesterase	153..710	CDD:278561	145/624 (23%)
		Aes	<263..>408	CDD:223730	55/149 (37%)
ges-1	NP_503411.1	COesterase	18..535	CDD:278561	145/624 (23%)
		Aes	<100..>211	CDD:223730	46/118 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810