Protein Alignment Nlg1 and ges-1

DIOPT Version :10

• Sequence 1: NP_731172.2
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_503411.1
• Gene: ges-1 / 178633
• WormBaseID: WBGene00001578
• Length: 562
• Species: Caenorhabditis elegans
• Alignment Length: 636
• Identity: 151/636 - (23%)
• Similarity: 246/636 - (38%)
• Gaps: 188/636 - (29%)

  Fly   158 IQVKQGRLMGITRRFQVTSGLRQVDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLPPVCP 222
            ::...|::.||.        ....:.||.:|:|:.|..:.||..|.||.||:.:..|       .
 Worm    20 VETNYGKVEGIE--------YEGAEVFLAIPFAKPPVDDLRFEKPVAPDPWEDVYPA-------T 69

  Fly   223 QKLPDLSPHGSENMSRARHKHLSRLLPYLRTESEDCLYLNLYVPHEEPQSTPKQYAVLVYLHGES 287
            |...|.:||         ::.:::...|   ..||||.||:..| ::.:..|    ||.::||..
 Worm    70 QYRNDCTPH---------YRLVAQFSSY---SGEDCLTLNIIKP-KKAEKLP----VLFWIHGGG 117

  Fly   288 FEWNS----GNPYDGSVLSSYGEVIVVTVNYRLGVLGFL-RPSIDAHNIANYALLDQIAALHWIK 347
            :|..|    |..:.....:|.| |||.||.||||.:||. ..:.|..  .|:.|.||.|||.::|
 Worm   118 YEIGSASQHGYEFFAKRYASQG-VIVATVQYRLGFMGFFSEGTSDVQ--GNWGLFDQAAALEFVK 179

  Fly   348 ENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASGLFHRAILMSGSAMSDWAASNQSLQLTMQI 412
            .|||.||||.:::|:.|:|.|||.|:.|.:||.....:.:||:||.|:...||.....::.:.|:
 Worm   180 SNIENFGGDPNQITIWGYSAGAASVSQLTMSPYTRDSYSKAIIMSASSFVGWATGPNVVETSKQL 244

  Fly   413 AHALECP---LNEHVEAEDDDVLLDCLRHRRYQ----DILHIPTALTQFSTSLGPIVDGHVIPNQ 470
            |..|.||   ..|.::.:....:.|.:..:.:.    |||.           ..|::||..:...
 Worm   245 AEILGCPWPGAKECMKKKSLHEIFDAIEVQGWTTGTIDILR-----------WSPVIDGDFMTKN 298

  Fly   471 PYKVMGHYTEHFSRYDLLFGITESESYHTLAALALEEGL-------------------------- 509
            |.::                |.||....||..::.:||.
 Worm   299 PEEL----------------IKESPVKPTLIGMSNKEGSYFAALNMGRVIADFGLSPEDMPKVDE 347

  Fly   510 --------------------RENERDNLLRFYMQSRFDIRPDLALAATLKK----YQDMYNNPIK 550
                                ||...:::|.||::..   :|     |.:|.    |.|.|:
 Worm   348 EFISEIIGRKLLYNNRYGENREKVWNDILDFYVKQG---KP-----AEVKDLNGFYVDRYS---- 400

  Fly   551 ATNLEHRDVVLDILSDARVVGPLLQTGMFHADVNRRN--YMYVFGHNSATGPFAHLPHSIMG--- 610
                       ::|||.....|:|:.  ..:.|.|:.  :.|...|........|:|....|
 Worm   401 -----------ELLSDITFNVPILRE--ITSRVERKTPVWTYRMDHYDKNIWKKHIPEQARGSPH 452

  Fly   611 -EELAFIFGAP-LAAAGPFPSGNYTVQEKLLSEAVMAYWTNFVKTGNPKAPWKGIFINSHALEWD 673
             .|..::|..| :|........:..:|..|:...:     :|.|||.|:..
 Worm   453 ANEYHYLFDMPVMAKIDMKKEPDSWIQNDLIDMVI-----SFAKTGVPQIE-------------- 498

  Fly   674 RYDLDW-PEFNRRAQAYLNI---GIPPTVGYKYRQIYMNFWNKELPDELNQ 720
              |::| |..:.....:|||   |:  ::.:...|..:.|||     ||.|
 Worm   499 --DVEWRPVSDPDDVNFLNIRSDGV--SIEHGLFQEPLAFWN-----ELRQ 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_731172.2	COesterase	157..710	CDD:395084	145/624 (23%)
ges-1	NP_503411.1	COesterase	16..535	CDD:395084	145/624 (23%)