Protein Alignment Nlg1 and cest-10

DIOPT Version :9

• Sequence 1: NP_001246966.1
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_501133.3
• Gene: cest-10 / 177493
• WormBaseID: WBGene00016595
• Length: 579
• Species: Caenorhabditis elegans
• Alignment Length: 617
• Identity: 143/617 - (23%)
• Similarity: 240/617 - (38%)
• Gaps: 144/617 - (23%)

  Fly   158 IQVKQGRLMGITRRFQVTSGLRQVDQ------FLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARH 216
            ::...|:|.|              ||      |..:|:|:.|.|..||..|.....|.|::.|:.
 Worm    24 VETSLGKLNG--------------DQIGNFHLFKKIPFAKPPLGKLRFQKPQPAETWNGVRNAKD 74

  Fly   217 LPPVCPQKLPDLSPHGSENMSRARHKHLSRLLPYLRTESEDCLYLNLYVPHEEPQSTPKQYAVLV 281
            ..|.|              ||.:     |......:...||||:||::.  .|.....|..||::
 Worm    75 YGPAC--------------MSNS-----STTKTVQKWVDEDCLHLNIFT--SETCLKSKNCAVVI 118

  Fly   282 YLHGESFEWNSGNPY-DGSVLSSYG--EVIVVTVNYRLGVLGFLRPSIDAHNIA--NYALLDQIA 341
            ||||.:..::|...: |..:|.:|.  |::.|....|||:  |....::..:||  |.||.|.:.
 Worm   119 YLHGGNLHYDSAVMFNDTFLLHTYASQEIVFVIPAVRLGI--FSHFVVEDQSIAPNNLALFDMLQ 181

  Fly   342 ALHWIKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVAS---GLFHRAILMSGSAMSDWAASN 403
            |:.:.|.:|..|||:|.|.||:|||.|....:.|..|...:   .||.:.|.||.....|
 Worm   182 AMEFAKSDIHNFGGNNKRTTLLGHSYGGTVASMLSFSTKVNTDLSLFQQYISMSSPTNFD----- 241

  Fly   404 QSLQL----TMQIAHALEC-PLN-EHVEAEDDDVLL-DCLRHRRYQDILHIPTALTQFSTSLGPI 461
             :|:|    |.:.|....| |.| :.:.....:|.: |||:.:...::|.|..:|.:...   |:
 Worm   242 -TLELQVERTYRFAEHANCLPKNSKFMRKNQKEVYMRDCLKKKSASELLRIQRSLEEAGY---PV 302

  Fly   462 VDGHVIPNQPYK--VMGHYTEHFSRYDLLFGITESES-----YHTLA-ALALEEGLRENERDNLL 518
            ..|.|:....::  :...:.:..:....|.|.|:.||     |..:. ||..|.....||
 Worm   303 YGGSVMRGPIFQEVLERDFMDSPNNITSLTGCTKYESLVYDHYRNMGKALGFENYEEVNE----- 362

  Fly   519 RFYMQSRFDIRPDLALAATLKKYQ-DMYNNPIKATNLEHRDVVLDILSDARVVGPLLQTGMFHAD 582
                                 ||: |.....|:..|:::...::.|....||      ..:...:
 Worm   363 ---------------------KYRSDSKEGKIEFDNVKNATQIMLIQIRTRV------NKILKKN 400

  Fly   583 VNRRNYMYVFGHNSATGPFAHLPHSIMGEELAFIFGAPLAAAGPFPSGNYTVQEKLLSEAVMAYW 647
            :...:|.|.:.        .|..|:   ::|.||.|     ..||......::   |.....:.:
 Worm   401 IPAYHYEYAYP--------KHANHT---DDLFFIMG-----VHPFIQDENEIK---LGNFYRSMF 446

  Fly   648 TNFVKTGNPKAPWKGIFINSHALEWDRYDLDWPEFNRRAQAYLNIGIPPTVGYKYRQIYMNFWNK 712
            .||:|||||.....|..:|....    ::::|.|         ..|..|.:...:.|..:::|.|
 Worm   447 LNFIKTGNPGNGCDGANLNGSTY----FEVNWNE---------TTGERPVMKNNFEQKILDYWTK 498

  Fly   713 ---ELPDELNQIAAIQEQLQKPGQEVITGHMS 741
               |...|::.:..|:.:.| |...|.:.:.|
 Worm   499 NMIEFDREVSLLRNIKSRRQ-PASRVFSAYYS 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_001246966.1	COesterase	153..710	CDD:278561	134/581 (23%)
		Aes	<263..>408	CDD:223730	47/152 (31%)
cest-10	NP_501133.3	Abhydrolase	23..503	CDD:389770	136/588 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810