Protein Alignment Nlg1 and ace-3

DIOPT Version :9

• Sequence 1: NP_001246966.1
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_496963.1
• Gene: ace-3 / 175076
• WormBaseID: WBGene00000037
• Length: 607
• Species: Caenorhabditis elegans
• Alignment Length: 645
• Identity: 172/645 - (26%)
• Similarity: 277/645 - (42%)
• Gaps: 153/645 - (23%)

  Fly   157 EIQVKQGRLMGITRRFQVTSGLRQVDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLPPVC 221
            |:|.|    :|..|..:...|.::|..|||:|:||.|....||..|....||.|...|..|.|.|
 Worm    33 EVQTK----LGTVRGTESDHGNKRVRSFLGVPFAEPPINEHRFKKPTPARPWNGTISANTLSPAC 93

  Fly   222 PQKLPDLSP--HGSENMSRARHKHLSRLLPYLRTESEDCLYLNLYVPHEEPQSTPKQYAVLVYLH 284
            .|......|  .||| |..|.           ...||||||:|::.|.:....|     |||:|.
 Worm    94 FQGRDSYDPTFWGSE-MWNAN-----------TPVSEDCLYVNIWAPADAYNLT-----VLVWLF 141

  Fly   285 GESFEWNSGNP----YDGSVLSSYGEVIVVTVNYRLGVLGFLRPSIDAHNI-ANYALLDQIAALH 344
            |..| | .|:|    |||..|::.|.||||.:|||:|..|:|  .:|..:: .|..:|||..||:
 Worm   142 GGGF-W-YGSPSLLLYDGKELATRGNVIVVNINYRVGPFGYL--FLDHEDVPGNMGMLDQQLALY 202

  Fly   345 WIKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASGLFHRAILMSGSAMSDWA--ASNQSLQ 407
            ||:::|.:|||:.:|::|:|.|.|||.:...:::|.:.|||...||.|||..:.|:  :..::.|
 Worm   203 WIRDHIFSFGGNPARISLVGESAGAASIVAHLIAPASKGLFQNGILQSGSLDNKWSMDSPKRAKQ 267

  Fly   408 LTMQIAHALECPLNEHVEAEDDDVLLDCLRHRRYQ-----------DILHIPTALTQFSTSLGPI 461
            .:..:|..:.|   ...:..|...   |||:...|           :.|..|.|:.....:....
 Worm   268 KSTALADLVGC---NQTKITDQTA---CLRNTPAQLLIDNIWNVGLNFLEFPFAIVSKDQNFFKH 326

  Fly   462 VDGHVIPNQPYKVMGHYTEHFSRYDLLFGITESE----SYHTLAAL----ALEEGLRENERDNLL 518
            :||.:...:     |.|:   :..:|:|||...|    :.:.||..    :::.||..:|
 Worm   327 LDGFIALRE-----GTYS---TDVNLMFGINHDEGNFWNIYNLAKFFDKQSVKPGLDRDE----- 378

  Fly   519 RFY--MQSRFDIRPDLALAATLKKYQDMYNNPIKATNLEHRDVVLDILSDARVVGPLLQTGMFHA 581
             |:  :.:.|.::|:  |..|..||                     :.||.:...|..:|..:..
 Worm   379 -FHECVDTAFAVQPE--LVRTAAKY---------------------VYSDPKCTDPKKKTDFYTE 419

  Fly   582 DVNR---------------RNY-----------MYVFGHNSATGPFAHLPHSIMGEELAFIFGAP 620
            .||:               .||           :|.|...|:..|:......:.|.|:.::||.|
 Worm   420 QVNQMVGDYFFTCDSIWFAHNYPKMAGNQSNVFVYYFDQPSSANPWPKWTGVMHGYEIEYVFGVP 484

  Fly   621 L--AAAGPFPSGNYTVQEKLLSEAVMAYWTNFVKTGNPKAPWKGIFINSHALEWDRYD----LDW 679
            |  ..||      ||.:|..:||.|:.:||.|..||.|....:.:. .:..::|||||    ..|
 Worm   485 LHNTTAG------YTKEEMDVSEKVIDFWTTFANTGVPSLRKRAVG-TTQKIKWDRYDGTDHTTW 542

  Fly   680 PEFNRRAQAYLNIGIPPTVGYKYRQIYMNFWN--KELPDELNQIAAIQEQLQKPGQEVIT 737
              .|.:..::..|       .:.:::..:.|.  |::     :.:|.:|:|.......:|
 Worm   543 --MNIKTGSFRMI-------QEIKKVECDLWRNAKDM-----EYSAYKEELATTSSSTLT 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_001246966.1	COesterase	153..710	CDD:278561	166/614 (27%)
		Aes	<263..>408	CDD:223730	56/151 (37%)
ace-3	NP_496963.1	COesterase	28..564	CDD:278561	166/614 (27%)
		Aes	<123..>234	CDD:223730	47/119 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910