Protein Alignment Nlg1 and ace-2

DIOPT Version :9

• Sequence 1: NP_001246966.1
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_491141.1
• Gene: ace-2 / 171905
• WormBaseID: WBGene00000036
• Length: 629
• Species: Caenorhabditis elegans
• Alignment Length: 621
• Identity: 171/621 - (27%)
• Similarity: 249/621 - (40%)
• Gaps: 154/621 - (24%)

  Fly   146 HVVPDKLQYTQEIQVKQGRLMGITRRFQVTSGLRQVDQFLGLPYAEAPTGNRRFMPPGAPLPWQG 210
            |||...|          |.:.|:.:.|...    :|..|||:|||:.|.|:|||........|.|
 Worm    39 HVVHTPL----------GTIRGVGQTFDGA----KVSAFLGVPYAKPPIGSRRFKMAEMIDRWSG 89

  Fly   211 LKIARHLPPVCPQKLPDLSPH--GSE--NMSRARHKHLSRLLPYLRTESEDCLYLNLYVPHEEPQ 271
            ...||.|...|...:....|.  |:|  |...|              .|||||.:|::||.:...
 Worm    90 ELEARTLAKTCYLTIDSAFPQFPGAEMWNPPGA--------------ISEDCLNMNIWVPEDHDG 140

  Fly   272 STPKQYAVLVYLHGESFEWNSGNP----YDGSVLSSYGEVIVVTVNYRLGVLGFLRPSIDAHNIA 332
            |      |:|:::|..|  .||.|    |.|||.::....|||.||||||..|||....|:....
 Worm   141 S------VMVWIYGGGF--FSGTPSLDLYSGSVFAAKEHTIVVNVNYRLGPFGFLYFGDDSPIQG 197

  Fly   333 NYALLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASGLFHRAILMSGSAMS 397
            |..|:||..||.|:.|||.|||||.|||||.|.|.|:|.....:.:|.:...|...|..|||.::
 Worm   198 NMGLMDQQLALRWVHENIGAFGGDRSRVTLFGESAGSASTTAHLFAPNSHKYFRNIIAKSGSIIN 262

  Fly   398 DWAASN--QSLQLTMQIAHALECPLNEHVEAEDDDVLLDCLRHRRYQDILHIPTALTQ-----FS 455
            .||::.  ..|.|:.::|..:.|      .:.|.:.::.|||        .:|..|.|     .|
 Worm   263 SWASATPPTMLDLSFRLAKKVNC------SSPDMNAIVKCLR--------SVPAHLVQAEADNIS 313

  Fly   456 TSLGPIVDGHVIP-----------------NQPYK-----VMGH----------YTEHFSRYDLL 488
            ..:||.:....:|                 |:.:|     :.|.          |.....:|...
 Worm   314 GDIGPPMTFAYVPVSSDANFFQGDVFQKLANKQFKKDVNIIFGSVKDEGTYWLPYYMSLPKYGFA 378

  Fly   489 FGIT-ESESYHTLAALA---LEEGLRENERDNLLRFYMQSRFDIRPDLALAATLKKYQDMYNNPI 549
            |..| .:|..|..|.:.   .||.:|.     .:.::..|:      |.|.|.:..|:.     :
 Worm   379 FNHTISAEDPHNRALITRDHYEESMRA-----FMPYFAGSK------LVLNAFMNSYEH-----V 427

  Fly   550 KATNL---EHRDVVLDILSDARVVGPLLQTGMF--HADVNRRN-----YMYVFGHNSATGPFAHL 604
            ..:|:   .:||.|      ||.:|.|..|...  .||:...|     |||.|.:.|:..|:...
 Worm   428 STSNVPEERYRDGV------ARFLGDLFFTCSLIDFADLISDNIFGNVYMYYFTYRSSANPWPKW 486

  Fly   605 PHSIMGEELAFIFGAPLAAAGPFPSGNYTVQEKLLSEAVMAYWTNFVKTGNPKAPWKGIFINSHA 669
            ...:.|.|:.:.||.|......:.. .:...||.||..:|..|.||..||
 Worm   487 MGVMHGYEIEYAFGQPYWRPHLYDQ-THLEDEKRLSSIIMQIWANFANTG--------------- 535

  Fly   670 LEWDRYDLDWPEFNRRAQAYLNIGIPPTVGYKYRQI 705
                |.|..||::|:..:..:.:| ..|:..|:|.|
 Worm   536 ----RTDSFWPQYNKIERKAIELG-ETTLQGKHRII 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_001246966.1	COesterase	153..710	CDD:278561	167/614 (27%)
		Aes	<263..>408	CDD:223730	60/150 (40%)
ace-2	NP_491141.1	COesterase	33..546	CDD:278561	165/598 (28%)
		Aes	<135..>233	CDD:223730	48/105 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910