Protein Alignment Nlg1 and LOC1281827

DIOPT Version :10

• Sequence 1: NP_731172.2
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: XP_061505289.1
• Gene: LOC1281827 / 1281827
• VectorBaseID: AGAMI1_012788
• Length: 737
• Species: Anopheles gambiae
• Alignment Length: 758
• Identity: 207/758 - (27%)
• Similarity: 323/758 - (42%)
• Gaps: 149/758 - (19%)

  Fly    17 GNHKLLSHVSPMGVAAEKQPLHKGNELENAMKLREAPKQSRVIGDITTTIQPDSDPGRSIGHQAL 81
            |:|:|   .:..||....|....|:.....|....|...|                  |....:|
Mosquito    52 GSHQL---SAAAGVGLASQSAQSGSLASGVMSSVPAAGAS------------------SSSSSSL 95

  Fly    82 RRAKAPPPSLELHFRQNLNKLFAGDETTHVGHTNATDNTTAAVLATDEGSSEHEPSTTHHPERRH 146
            ..:.|......:...::.:..|    |.::||     ..:..::..:.|:.||..|.. .|.||.
Mosquito    96 LSSSAEDDVARITLSKDADAFF----TPYIGH-----GESVRIIDAELGTLEHVHSGA-TPRRRG 150

  Fly   147 VV----------PDKLQYTQEIQVKQGRLMGITRRFQVTSGLRQVDQFLGLPYAEAPTGNRRFMP 201
            :.          .|.|    .:...:||:.|||  ....|| ::||.:||:|||:.|.|..||..
Mosquito   151 LTRRESNSDANDNDPL----VVNTDKGRIRGIT--VDAPSG-KKVDVWLGIPYAQPPVGPLRFRH 208

  Fly   202 PGAPLPWQGLKIARHLPPVCPQKLPDL----------SPHGSENMSRARHKHLSRLLPYLRTESE 256
            |.....|.|:......|..|.|.:..:          :|:                .|.    ||
Mosquito   209 PRPAEKWTGVLNTTTPPNSCVQIVDTVFGDFPGATMWNPN----------------TPL----SE 253

  Fly   257 DCLYLNLYVPHEEPQSTPKQYAVLVYLHGESFEWNSG----NPYDGSVLSSYGEVIVVTVNYRLG 317
            ||||:|:..    |:..||..||::::.|..|  .||    :.||...|:|...||||::.||:.
Mosquito   254 DCLYINVVA----PRPRPKNAAVMLWIFGGGF--YSGTATLDVYDHRALASEENVIVVSLQYRVA 312

  Fly   318 VLGFL---RPSIDAHNIANYALLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSP 379
            .||||   .|...    .|..|.||..||.|:::||..||||.|||||.|.|.||..|:..::|.
Mosquito   313 SLGFLFLGTPEAP----GNAGLFDQNLALRWVRDNIHRFGGDPSRVTLFGESAGAVSVSLHLLSA 373

  Fly   380 VASGLFHRAILMSGSAMSDWA-ASNQSLQL-TMQIAHALECPLNEHVEAEDDDVLLDCLRHRRYQ 442
            ::..||.||||.|||..:.|| .|.:...| .:::|.|:.||   |..::..|. ::|||.:...
Mosquito   374 LSRDLFQRAILQSGSPTAPWALVSREEATLRALRLAEAVGCP---HEPSKLSDA-VECLRGKDPH 434

  Fly   443 DILHIPTALTQFSTSLG-------PIVDGHVIPNQPYKVMGHYTEHFSRYDLLFGITESESYHTL 500
            .:::     .::.| ||       |:|||..:...|.:.:.  :..|.:.::|.|....|.|:.:
Mosquito   435 VLVN-----NEWGT-LGICEFPFVPVVDGAFLDETPQRSLA--SGRFKKTEILTGSNTEEGYYFI 491

  Fly   501 AALALEEGLRENERDNLLR-FYMQSRFDIRP---DLALAATLKKYQDMY--NNPIKATNLEHRDV 559
             ...|.|.||:.|...:.| .::|:..::.|   ..|..|.:.:|.|..  :||     ..:||.
Mosquito   492 -IYYLTELLRKEEGVTVTREEFLQAVRELNPYVNGAARQAIVFEYTDWTEPDNP-----NSNRDA 550

  Fly   560 VLDILSDARVVGPLLQTGMFHADVNRRNYMYVFGHNSATGPFAHLPHSIMGEELAFIFGAPLAAA 624
            :..::.|......:.:....:|:.....|||::.|.|...|:......:.|:|:.::||.||.
Mosquito   551 LDKMVGDYHFTCNVNEFAQRYAEEGNNVYMYLYTHRSKGNPWPRWTGVMHGDEINYVFGEPLN-- 613

  Fly   625 GPFPSGNYTVQEKLLSEAVMAYWTNFVKTGNPKAPWKGIFINSHALEWDRYDLDWPEFNRRAQAY 689
               |:..||..||..|..:|.||:||.|||||..       |:.:.|:.    :||:.....:.|
Mosquito   614 ---PTLGYTEDEKDFSRKIMRYWSNFAKTGNPNP-------NTASSEFP----EWPKHTAHGRHY 664

  Fly   690 LNIGIPPT-VGYKYRQIYMNFWNKELPDELNQIAAIQEQLQKP 731
            |.:|:..: ||...|.....||.|.||    |:.|....|..|
Mosquito   665 LELGLNTSFVGRGPRLRQCAFWKKYLP----QLVAATSNLPGP 703

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_731172.2	COesterase	157..710	CDD:395084	172/585 (29%)
LOC1281827	XP_061505289.1	None