Protein Alignment Nlg1 and LOC1281357

DIOPT Version :10

• Sequence 1: NP_731172.2
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: XP_061497244.1
• Gene: LOC1281357 / 1281357
• VectorBaseID: AGAMI1_013672
• Length: 1268
• Species: Anopheles gambiae
• Alignment Length: 1293
• Identity: 338/1293 - (26%)
• Similarity: 515/1293 - (39%)
• Gaps: 354/1293 - (27%)

  Fly   158 IQVKQGRLMGIT-RRFQVTSGLRQVDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLPPVC 221
            ::.|.|.|.||. |...|.     |:.|||:|||..|.|:.|:|||..|..|:..::.....|||
Mosquito    60 VKTKYGPLRGIVFRTVPVV-----VEGFLGVPYASPPIGSLRYMPPVTPSTWKAPRLVDRFAPVC 119

  Fly   222 PQKLPDLSPHGSE-----NMSRARHKHLSRLLPYLRTESEDCLYLNLYVPHEEPQSTPKQY--AV 279
            |||||.|.  |::     ::...|.|.|.||:|.|..:|||||||||||||.|..:....:  ..
Mosquito   120 PQKLPKLD--GTDAGVLGDLPIDRLKQLRRLVPTLVNQSEDCLYLNLYVPHAEDTAHRPDHLKPS 182

  Fly   280 LVYLHGESFEWNSGNPYDGSVLSSYGEVIVVTVNYRLGVLGFLRPSIDAHNIANYALLDQIAALH 344
            :||:||||:||||||.||||.|:..|.|||||:|:||||||||:.........|:.|:|.:|.||
Mosquito   183 IVYIHGESYEWNSGNHYDGSTLAMNGNVIVVTINFRLGVLGFLKTGAKGSAQGNFGLMDLVAGLH 247

  Fly   345 WIKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASGLFHRAILMSGSAMSDWAASNQSLQLT 409
            |::||:.|||||.:::|||||.||||..|.|.|||||..|.||.:|:||||:|.||.....|.:.
Mosquito   248 WLRENLVAFGGDPAKITLMGHGTGAALANILAVSPVAGDLIHRVVLLSGSALSPWAIQRDPLSVK 312

  Fly   410 MQIAHALECPLNEHVEAEDDDVLLDCLRHRRYQDILHIPTALTQFSTSLGPIVDGHVIPNQPYKV 474
            .::|....|  ...|..||   |..|||.:...::::|..:..:|.....|.|||.||......|
Mosquito   313 RKVAQQTSC--TGDVVNED---LAPCLRTKSLAELMNISLSSPRFLPGFAPFVDGTVITPAKAAV 372

  Fly   475 M---------------GHYTEHFSRYDLLFGITESESYHTLAALALEEGLRENERDNLLRFYMQS 524
            :               |....:|.:.|:|||:|..|||..|.|..||.|..|.:||.:||.::::
Mosquito   373 INNLKIPTDSAIASTSGIEFSNFHKQDVLFGLTTYESYLELTAADLEFGFNETKRDRILRTFVRN 437

  Fly   525 RFDIRPDLALAATLKKYQDMYNNPIKATNLEHRDVVLDILSDARVVGPLLQTGMFHADVNRRNYM 589
            .:....:...:|...:|.:...:|..|..  :||.||::|||.....||:|....|:....|:|.
Mosquito   438 TYRYHLNEIYSALKNEYTNWERSPRSAYG--YRDAVLELLSDGLTAAPLVQLSHLHSLQGGRSYF 500

  Fly   590 YVFGHNSATGPFAHLPHSIMGEELAFIFG---APLAAAGPFPSGNYTVQEKLLSEAVMAYWTNFV 651
            ..|.|.|....|.....|:.||::.|..|   :|:     ||. ..|..:..:|..||.|..|||
Mosquito   501 LHFKHQSHEWKFPQRTGSVRGEDVPFALGFSPSPM-----FPL-TLTRLDMQVSSTVMRYLCNFV 559

  Fly   652 KTGNP---KAPWKGIFINSHALEWDRYDLDWPEFNRRAQAYLNIGIPPTVGYKYRQIYMNFWNKE 713
            |||||   :.|...:|:||:              |:|:   .|....|......||:..:|..::
Mosquito   560 KTGNPNGLRTPRMDVFVNSN--------------NKRS---WNPAKKPHNETLMRQLVSSFRQQD 607

  Fly   714 LPDE-LNQIAAIQEQ-LQKPGQEVITGHMSKYGPRD-HGAEDPVRTLKLLLQEPSLAGPTQSGES 775
            .|.: .|.:..:..| |..|.|.::...:.:|..:: ..|..|..:.:   :....:...|...|
Mosquito   608 PPPQPRNPLPGMPAQPLLTPEQALMQQQLQQYYRKEQQSARQPKHSRR---KRTRFSNDLQRYGS 669

  Fly   776 TETAAENMYNAPPTFGHVHKMQGGSDFEDLVTSTNSLESGEDHPQAPPETVAKSEATMQLLIALI 840
            :|.||   |.:....|.:    |||       :.|....|:|
Mosquito   670 SEGAA---YGSSEEAGTL----GGS-------NGNGGRGGDD----------------------- 697

  Fly   841 TIIIVLNLLIYGTFLLRQRRRRAKALPFPAPKLGGTILSYDGANDEELKRCSKSRDGDDSFVLEM 905
                                                    :...:||.:.....|||.:|.....
Mosquito   698 ----------------------------------------EDDEEEEEEENGDRRDGGESGGRSE 722

  Fly   906 TRKSNTYEAIKTGQRSLSCSTV----------DTHTKVCEWMSSQEAPKSGSFNTATPPPQPILS 960
            |..|  |.::.:.......:|:          ||..:|...:.||..|||
Mosquito   723 TEPS--YYSVDSDYVYSGFTTIKYNLPFWGHYDTTNQVFMEIGSQVVPKS--------------- 770

  Fly   961 DGRLIICQDIEVADAALLIPQHM--HEPQHYEMLLQRQHSALTEPSDEILQQQYPLRNHSHSHSD 1023
                                 |.  |:...:..|:.:.||:...|       :..:|:|..|..:
Mosquito   771 ---------------------HYRGHKLSLWLSLIPQLHSSFNIP-------ELSMRHHHFSEEN 807

  Fly  1024 PV-------DMILAADEQVTSFVHADDVDINVTSRDDSDGLEVIPLTSAQQLELLR--QRNYP-- 1077
            |:       :.|:........||.:....::.|....|..|:.|.......:..::  ..::|
Mosquito   808 PMFYDGLVREQIIEPPLMHIGFVTSTTSKMHKTETIASTILQSISTECPPNITFIQTASASWPLH 872

  Fly  1078 -KVLPTE-----QDLIN---SSYKRNSLPPQNFNAPLPPPRTISNTLG----------------- 1116
             ..|||:     :.|||   :||.|:.            ...::.|:|
Mosquito   873 NSALPTQHGDSNRSLINRLTNSYHRSY------------STALAITIGVGCFLLFLNVLIFVAIY 925

  Fly  1117 --RRRRDSSNITTSPLQVARDCGGEDEDLKEPQITQNTLIVGPIVPKSPASSLKRVKRMPESSAM 1179
              |.:|:|:    |.:::         :|.|.:...|       |.:|.:.::...     ::|.
Mosquito   926 YQREKRESN----SRMKI---------NLLELESRLN-------VVESSSGAVAAA-----AAAA 965

  Fly  1180 TALSGSFQ---SFEAVPPAHE----------------------TT------PPQGGERTECIYAI 1213
            .|.||..:   ||...||.|:                      ||      .|.||.....|..|
Mosquito   966 AAASGEVKEETSFSVAPPPHQEDDGPASHTKGAPLRVASSASSTTATSAKAAPGGGSGPNSIQTI 1030

  Fly  1214 RPSPGSCSWAAP--NGDLYAQPMKSSSRNSLIPRPTKPAESQSQATPAGPAGESLGSTGMATASR 1276
            ..|      ..|  :|..:|..|:.||.:::  :.:...|.|.|
Mosquito  1031 ELS------LTPHYHGHGHATSMRRSSTSAI--KHSHKCELQQQ--------------------- 1066

  Fly  1277 IPQLQRQASGKDLQARTATDNTANPLGCQPRTDSTISSGSSASYASTTDSSSSSSTGT 1334
              |.|:|......|:..:::.|.:     |:..|.:|...|...:|   |.|:||.||
Mosquito  1067 --QQQQQHLYHHHQSSCSSNRTVS-----PKKVSIVSPNPSDDQSS---SGSASSLGT 1114

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_731172.2	COesterase	157..710	CDD:395084	217/580 (37%)
LOC1281357	XP_061497244.1	None