Protein Alignment Nlg1 and LOC1280747

DIOPT Version :10

• Sequence 1: NP_731172.2
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: XP_061513099.1
• Gene: LOC1280747 / 1280747
• VectorBaseID: AGAMI1_007562
• Length: 1118
• Species: Anopheles gambiae
• Alignment Length: 1144
• Identity: 315/1144 - (27%)
• Similarity: 486/1144 - (42%)
• Gaps: 236/1144 - (20%)

  Fly   158 IQVKQGRLMGITRRFQVTSGLRQVDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLPPVCP 222
            :..|.|.:.|:..... :..|..|:.|..:|||..|.|:.||.||....||:|.|:|.....|||
Mosquito    75 VDTKSGAIRGVILELN-SKHLEPVEVFKAVPYATPPIGSLRFEPPKKLPPWKGTKLADTFGSVCP 138

  Fly   223 QKLPDLSPHGSE--NMSRARHKHLSRLLPYLRTESEDCLYLNLYVPHEEPQSTPKQYAVLVYLHG 285
            |..||:|...:.  :|.:.|::||.||.|.|..:|||||.||:|||....:.....|::..|:||
Mosquito   139 QSFPDISNRTAALLSMPKGRYQHLKRLQPLLANQSEDCLTLNIYVPGSGSRGLEAPYSIFFYIHG 203

  Fly   286 ESFEWNSGNPYDGSVLSSYGEVIVVTVNYRLGVLGFL--RPSIDAHNIANYALLDQIAALHWIKE 348
            |:::|.||||||||||:|||.|||||||:|||:||||  |.|:...:..|..|:|.|.||.|:::
Mosquito   204 EAYDWGSGNPYDGSVLASYGHVIVVTVNFRLGILGFLKTRASLSPGSGGNLGLMDIILALQWVRD 268

  Fly   349 NIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASGLFHRAILMSGSAMSDWAASNQSLQLTMQIA 413
            ||.:||||..|:|::||.||||..|..::|....||..||||:||||:|.||.......:.::::
Mosquito   269 NIASFGGDPKRITIVGHDTGAALANLALISKAGKGLVQRAILLSGSALSPWALIPDPDAVRLEVS 333

  Fly   414 HALECPL----NEHVEAEDDDVLLDCLRHRRYQDILHIPTALTQFSTSLGPIVDGHVIPNQ---- 470
            ..:.|.|    |......||  :.:|||.:..:.::.:.....:|..|.||.     :|.:
Mosquito   334 QQMACHLVPGRNGRKPTTDD--ITECLRDKPIEALMGVRLTSVRFMPSWGPF-----LPLEDSMD 391

  Fly   471 PYKVMGHYTEHFSRYDLLFGITESESYHTLAALALEEGLRENERDNLLRFYMQSRFDIRPDLALA 535
            |...|.|..|.|...:|:.|:|.:|||...:|..::.||.|::|:.|||.|:::.|....:...:
Mosquito   392 PEFAMEHSGEGFITSELMLGMTTTESYSDFSASDIQYGLEEDQRNRLLRTYIRNAFTFHLNEIFS 456

  Fly   536 ATLKKYQDMYNNPIKATNLEHRDVVLDILSDARVVGPLLQTGMFHADVNRRNYMYVFGHNSATGP 600
            |...:|.| ::.||:.. :..||..::.|||...|.|:::....||....:.||:.||:.|....
Mosquito   457 AVRNEYTD-WDKPIQHP-INIRDSTMEALSDGHTVAPIIKVAYLHARRGAKTYMFHFGYQSKESE 519

  Fly   601 FAHLPHSIMGEELAFIFGAPLAAAGP-FPSGNYTVQEKLLSEAVMAYWTNFVKTGNPK------- 657
            :.....|:.||:|.:|||.||...|| ||. ||:.|:..::|||:.:.|||.|||:|.
Mosquito   520 YPQRLGSVRGEDLPYIFGLPLVQGGPVFPQ-NYSRQDMGVNEAVLNFVTNFCKTGDPNEAGHQQA 583

  Fly   658 APWKGIFINSHALEWDRYDL-DWPEFNRRAQAYLNIGIPPTVGYKYRQIYMNFWNKELPDELNQI 721
            ||....:  ..|.|..|:.| .|..:....|.||:|...|.:...||...|..|...:|
Mosquito   584 APLHPDY--GTAKERTRFRLITWETYETTTQQYLSISTKPKMRSHYRGHKMALWLNLIP------ 640

  Fly   722 AAIQEQLQKPGQEVITGHMSKYGPRD-HGAEDPVRTLKLLLQEPSLAGPT---QSG------EST 776
                 ||.:||...::.....:..|: |.....||.       .|.:.|.   |:|      ||.
Mosquito   641 -----QLHRPGDPEVSMRHHHFREREPHYYAGSVRA-------ESFSRPRSLYQNGVINDAQESR 693

  Fly   777 ETAAENMYNAPPTFGHV---HKMQGGSDFEDLVTSTNSLESGEDHPQAPPETVAKSE-----ATM 833
            :.:........||.|.|   :.:.||....|.:|:..|    |:..:...|.:|...     |.:
Mosquito   694 QESFGTECTPDPTMGEVLQENGVGGGGGPGDTLTNVLS----EEEEEELLEKLANRHYYSYTAAL 754

  Fly   834 QLLIALITIIIVLNLLIY-GTFLLRQRRRRAKALPFPAPKLG------GTILSYDGAN----DEE 887
            .:.:.:..::::||:||: |.:..|.|.:|.......:..:|      ||..|..|:|    :.|
Mosquito   755 GVTVGVGCLLLLLNMLIFAGIYYQRDRTKRKSQTSQSSGTVGGSGVTSGTSASLSGSNGTPDESE 819

  Fly   888 LK----------RCSKSRDGDDSFVLEMTRKSNTYEAIKTGQRSLSCSTVDTHTKVCEWMSSQEA 942
            :.          :..::.:...|:.....|..|  ....||...........|..:....|..:.
Mosquito   820 IPLTSIPSPSPVKAKRTIEPPPSYATLPKRTGN--NGASTGIHHQHQHHHHLHQHLAGGSSGTKD 882

  Fly   943 PKSGSFNTATPPPQPILSDGRLIICQ-------DIEVADAALLIPQHMHEPQHYEMLLQRQ---- 996
            .|.||     ||....|..|...:.:       |...:..    .||..:.|.|   |.:|
Mosquito   883 TKLGS-----PPTSTHLRTGASTLGRSGTGSFYDSSTSSR----QQHQQQQQPY---LTQQVIAP 935

  Fly   997 ------HSALT-EPSDEILQQQYPLRNHSHSHSDPVDMILAADEQVTSFVHADDVDINVTSRDDS 1054
                  |:|:| .|:...:.....|...|.:...|:.....:..             :.:|...:
Mosquito   936 HSTNVGHTAVTITPAAATVSHHQTLPRASKAPLPPIRSTTCSSS-------------SASSSSGT 987

  Fly  1055 DGLEVIPLTSAQQLELLRQRNYPKVLPTEQDLINS----SYKRNSLPPQNF--------NAPLPP 1107
            ....|:||||.                    |:||    :...|:..|.::        ||.|||
Mosquito   988 ASTSVVPLTSI--------------------LVNSNSTTTNNNNNHQPHHYQQQSCEMANATLPP 1032

  Fly  1108 --------------------------PRTISNTLGRRRRD--------------SSNITTSPLQV 1132
                                      |.|:   ||:.:..              |.::||.
Mosquito  1033 QPNSSVITVDLVSSATVAAAAATGSSPPTV---LGQHQHQHHHHHHHAHHHASGSGSVTTG---- 1090

  Fly  1133 ARDCGGEDEDLKEPQITQNTLIVGPIVPKSPASSLKRVK 1171
            :...||                 ||..|.|.|:..|||:
Mosquito  1091 SGPAGG-----------------GPAAPGSTATLKKRVQ 1112

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_731172.2	COesterase	157..710	CDD:395084	210/572 (37%)
LOC1280747	XP_061513099.1	None