Protein Alignment Nlg1 and Ces1g

DIOPT Version :9

• Sequence 1: NP_001246966.1
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_067431.2
• Gene: Ces1g / 12623
• MGIID: 88378
• Length: 565
• Species: Mus musculus
• Alignment Length: 601
• Identity: 164/601 - (27%)
• Similarity: 280/601 - (46%)
• Gaps: 91/601 - (15%)

  Fly   158 IQVKQGRLMGITRRFQVTSGLRQ-VDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLPPVC 221
            :....|:::|   ::....|..| |..|||:|:|:.|.|:.||.||....||..:|.....||:|
Mouse    26 VHTVHGKVLG---KYVTLEGFSQPVAVFLGVPFAKPPLGSLRFAPPEPAEPWSFVKHTTSYPPLC 87

  Fly   222 PQKLPDLSPHGSENMSRARHKHLSRLLPYLRTESEDCLYLNLYVPHEEPQSTPKQYAVLVYLHGE 286
            .|. |:.:...:|..:..|     :::|:  ..||||||||:|.|.:..|::  :..|:|::||.
Mouse    88 YQN-PEAALRLAELFTNQR-----KIIPH--KFSEDCLYLNIYTPADLTQNS--RLPVMVWIHGG 142

  Fly   287 SFEWNSGNPYDGSVLSSYGEVIVVTVNYRLGVLGFLRPSIDAHNIANYALLDQIAALHWIKENIE 351
            ....:..:.|||..|:.:..|:||.:.||||:.||.... |.|:..|:..|||:|||||:::||.
Mouse   143 GLVIDGASTYDGVPLAVHENVVVVVIQYRLGIWGFFSTE-DEHSRGNWGHLDQVAALHWVQDNIA 206

  Fly   352 AFGGDNSRVTLMGHSTGAACVNYLMVSPVASGLFHRAILMSGSAMSDWAASNQSLQLTMQIAHAL 416
            .|||:...||:.|.|.|...|:.|::||:|..||||||..|....:.......:..|..:||...
Mouse   207 NFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAIAQSSVIFNPCLFGRAARPLAKKIAALA 271

  Fly   417 ECPLNEHVEAEDDDVLLDCLRHRRYQDILHIPTALTQFST------------SLGPIVDGHVIPN 469
            .|      :......::.|||.:...::|.:...: :|.|            .|..::||.::|.
Mouse   272 GC------KTTTSAAMVHCLRQKTEDELLEVSLKM-KFGTVDFLGDPRESYPFLPTVIDGVLLPK 329

  Fly   470 QPYKVMGHYTEHFSRYDLLFGITESESYHTLAALALEEGLRENERDN------LLRFYMQSRFDI 528
            .|.:::..  :.|:....:.||.:.| :..:..:.|:..|.|.:.|.      |.:.|
Mouse   330 APEEILAE--KSFNTVPYMVGINKHE-FGWIIPMFLDFPLSERKLDQKTAASILWQAY------- 384

  Fly   529 RPDLALA-----ATLKKYQDMYNNPIKATNLEHRDVVLDILSDARVVGPLLQTGMFHADVNRRNY 588
             |.|.::     |.::||.....:|...|     |:.||::.|.....|.:.....|.|.....|
Mouse   385 -PILNISEKLIPAAIEKYLGGTEDPATMT-----DLFLDLIGDIMFGVPSVIVSRSHRDAGAPTY 443

  Fly   589 MYVFGHNSATGPFA--HLPHSIMG---EELAFIFGAPLAAAGPFPSGNYTVQEKLLSEAVMAYWT 648
            ||.:.:..:   |.  ..|..::|   :||..::|||....|.      :.:|..||:.||.:|.
Mouse   444 MYEYQYRPS---FVSDDRPQELLGDHADELFSVWGAPFLKEGA------SEEEINLSKMVMKFWA 499

  Fly   649 NFVKTGNPKAPWKGIFINSHALEWDRYDLDWPEFNRRAQAYLNIGIPPTVGYKYRQIYMNFWNKE 713
            ||.:.|||         |...|.      .|||:::: :.||.||:|....::.:...::||.:.
Mouse   500 NFARNGNP---------NGEGLP------HWPEYDQK-EGYLQIGVPAQAAHRLKDKEVDFWTEL 548

  Fly   714 LPDELNQIAAIQEQLQ 729
            ...|..:.::.:|.::
Mouse   549 RAKETAERSSHREHVE 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_001246966.1	COesterase	153..710	CDD:278561	160/580 (28%)
		Aes	<263..>408	CDD:223730	53/144 (37%)
Ces1g	NP_067431.2	COesterase	24..545	CDD:278561	160/580 (28%)
		Aes	<121..>239	CDD:223730	46/120 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810