Protein Alignment Nlg1 and Bche

DIOPT Version :9

• Sequence 1: NP_001246966.1
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: XP_011238302.1
• Gene: Bche / 12038
• MGIID: 894278
• Length: 615
• Species: Mus musculus
• Alignment Length: 624
• Identity: 175/624 - (28%)
• Similarity: 267/624 - (42%)
• Gaps: 115/624 - (18%)

  Fly   148 VPDKLQYTQE---IQVKQGRLMGITRRFQVTSGLRQVDQFLGLPYAEAPTGNRRFMPPGAPLPWQ 209
            :|....:|:|   |..|.||:.|::  ..|..|  .|..|||:|||:.|.|:.||..|.....|.
Mouse    34 MPFGKSHTEEDFIITTKTGRVRGLS--MPVLGG--TVTAFLGIPYAQPPLGSLRFKKPQPLNKWP 94

  Fly   210 GLKIARHLPPVCPQKLPDLSP--HGSE------NMSRARHKHLSRLLPYLRTESEDCLYLNLYVP 266
            .:..|......|.|.:....|  .|||      |:                  ||||||||:::|
Mouse    95 DIHNATQYANSCYQNIDQAFPGFQGSEMWNPNTNL------------------SEDCLYLNVWIP 141

  Fly   267 HEEPQSTPKQYAVLVYLHGESFEWNSGN--PYDGSVLSSYGEVIVVTVNYRLGVLGFLRPSIDAH 329
            ..:    ||...|:|:::|..|:..:.:  .|||..|:....||||::|||:|.||||....:..
Mouse   142 VPK----PKNATVMVWIYGGGFQTGTSSLPVYDGKFLARVERVIVVSMNYRVGALGFLAFPGNPD 202

  Fly   330 NIANYALLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASGLFHRAILMSGS 394
            ...|..|.||..||.|::.||.||||:...:|:.|.|.|||.|:..::.|.:..||.||||.|||
Mouse   203 APGNMGLFDQQLALQWVQRNIAAFGGNPKSITIFGESAGAASVSLHLLCPQSYPLFTRAILESGS 267

  Fly   395 AMSDWAASN--QSLQLTMQIAHALECPLNEHVEAEDDDVLLDCLRHRRYQDILH-----IPTALT 452
            :.:.||..:  ::...|:.:|....|.....:|      ::.|||.:..|:||.     :|:. :
Mouse   268 SNAPWAVKHPEEARNRTLTLAKFTGCSKENEME------MIKCLRSKDPQEILRNERFVLPSD-S 325

  Fly   453 QFSTSLGPIVDGHVIPNQPYKVMGHYTEHFSRYDLLFGITESESYHTLAALALEEGLRENERDNL 517
            ..|.:.||.|||..:.:.|:.::  ......:..:|.|:.:.|.   .|.|.........:.|:|
Mouse   326 ILSINFGPTVDGDFLTDMPHTLL--QLGKVKKAQILVGVNKDEG---TAFLVYGAPGFSKDNDSL 385

  Fly   518 LRFYMQSRFDIRPDLALAATLKKYQD---MYNNPIKATNLE-----------------HRDVVLD 562
            :                  |.|::|:   ||...:.....|                 :||.:.|
Mouse   386 I------------------TRKEFQEGLNMYFPGVSRLGKEAVLFYYVDWLGEQSPEVYRDALDD 432

  Fly   563 ILSDARVVGPLLQTGMFHADVNRRNYMYVFGHNSATGPFAHLPHSIMGEELAFIFGAPLAAAGPF 627
            ::.|..::.|.|:.....|::....:.|.|.|.|:..|:......:.|.|:.|:||.||..
Mouse   433 VIGDYNIICPALEFTKKFAELENNAFFYFFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLGR---- 493

  Fly   628 PSGNYTVQEKLLSEAVMAYWTNFVKTGNPKAPWKGIFINSHALEWDRYDLDWPEFNRRAQAYLNI 692
             ..|||..|::.|.::|..|.||.|.|:|    .|...||..         ||.|....|.||.:
Mouse   494 -RVNYTRAEEIFSRSIMKTWANFAKYGHP----NGTQGNSTM---------WPVFTSTEQKYLTL 544

  Fly   693 GIPPTVGY-KYRQIYMNFWNKELPDELNQIAAIQEQLQK 730
            ....:..| |.|.....||....|..|.....|.|..|:
Mouse   545 NTEKSKIYSKLRAPQCQFWRLFFPKVLEMTGDIDETEQE 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_001246966.1	COesterase	153..710	CDD:278561	167/597 (28%)
		Aes	<263..>408	CDD:223730	55/148 (37%)
Bche	XP_011238302.1	COesterase	46..563	CDD:365897	165/590 (28%)
		AChE_tetra	578..612	CDD:370053	2/6 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910