Protein Alignment Nlg1 and Ces1d

DIOPT Version :9

• Sequence 1: NP_001246966.1
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_579829.3
• Gene: Ces1d / 113902
• RGDID: 70896
• Length: 565
• Species: Rattus norvegicus
• Alignment Length: 598
• Identity: 175/598 - (29%)
• Similarity: 277/598 - (46%)
• Gaps: 105/598 - (17%)

  Fly   158 IQVKQGRLMGITRRFQVTSGLRQ-VDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLPPVC 221
            :...:|:::|   ::....|..| |..|||:|:|:.|.|:.||.||....||..:|.....||:|
  Rat    26 VNTVKGKVLG---KYVNLEGFAQPVAVFLGIPFAKPPLGSLRFAPPQPAEPWNFVKNTTSYPPMC 87

  Fly   222 PQK------LPDLSPHGSENMSRARHKHLSRLLPYLRTESEDCLYLNLYVPHEEPQSTPKQYAVL 280
            .|.      |.:|..:..||:.          |.:    ||||||||:|.|.:..:::  :..|:
  Rat    88 SQDAVGGQVLSELFTNRKENIP----------LQF----SEDCLYLNVYTPADLTKNS--RLPVM 136

  Fly   281 VYLHGESFEWNSGNPYDGSVLSSYGEVIVVTVNYRLGVLGFLRPSIDAHNIANYALLDQIAALHW 345
            |::||........:.|||.|||::..|:|||:.||||:.||.... |.|:..|:..|||:|||||
  Rat   137 VWIHGGGLVVGGASTYDGQVLSAHENVVVVTIQYRLGIWGFFSTG-DEHSQGNWGHLDQVAALHW 200

  Fly   346 IKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASGLFHRAILMSGSAMSDWAASNQSLQLTM 410
            :::||..|||:...||:.|.|.|...|:.|::||:|..||||||..||..::....:..|..:..
  Rat   201 VQDNIANFGGNPGSVTIFGESAGGFSVSALVLSPLAKNLFHRAISESGVVLTSALITTDSKPIAN 265

  Fly   411 QIAHALECPLNEHVEAEDDDVLLDCLRHRRYQDILHIPTALTQFSTSL--GP---------IVDG 464
            .||....|      :.....|::.|||.:...::|.....|..|...|  .|         ::||
  Rat   266 LIATLSGC------KTTTSAVMVHCLRQKTEDELLETSLKLNLFKLDLLGNPKESYPFLPTVIDG 324

  Fly   465 HVIPNQPYKVMGHYTE-HFSRYDLLFGITESE---SYHTLAALALEEG-LRENERDNLL-RFYMQ 523
            .|:|..|.:::   || .|:....:.||.:.|   ...||....|.|| |.:....:|| :.|
  Rat   325 VVLPKTPEEIL---TEKSFNTVPYIVGINKQEFGWIIPTLMGYPLSEGKLDQKTAKSLLWKSY-- 384

  Fly   524 SRFDIRPDLALAATL-----KKYQDMYNNPIKATNLEHRDVVLDILSDARVVGPLLQTGMFHADV 583
                  |.|.::..:     :||....::|.|     .:|:..|:::|.....|.:.....|.|.
  Rat   385 ------PTLKISEKMIPVVAEKYFGGTDDPAK-----RKDLFQDLVADVMFGVPSVMVSRSHRDA 438

  Fly   584 NRRNYMYVFGHNSATGPF--AHLPHSIM---GEELAFIFGAPLAAAGPFPSGNYTVQEKLLSEAV 643
            ....:||.|.:..:   |  |..|.:::   |:||..:||:|....|.      :.:|..||:.|
  Rat   439 GAPTFMYEFEYRPS---FVSAMRPKTVIGDHGDELFSVFGSPFLKDGA------SEEETNLSKMV 494

  Fly   644 MAYWTNFVKTGNPKAPWKGIFINSHALEWDRYDLDWPEFNRRAQAYLNIGIPPTVGYKYRQIYMN 708
            |.||.||.:.|:|         |...|.      .|||:::: :.||.||.......:.:...:.
  Rat   495 MKYWANFARNGSP---------NGGGLP------HWPEYDQK-EGYLKIGASTQAAQRLKDKEVA 543

  Fly   709 FWN----KELPDE 717
            ||:    ||..:|
  Rat   544 FWSELRAKEAAEE 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_001246966.1	COesterase	153..710	CDD:278561	170/585 (29%)
		Aes	<263..>408	CDD:223730	57/144 (40%)
Ces1d	NP_579829.3	COesterase	24..545	CDD:278561	170/585 (29%)
		Aes	<121..>239	CDD:223730	48/120 (40%)
		Prevents secretion from ER. /evidence=ECO:0000255	562..565

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910