Protein Alignment Nlg1 and Ces2a

DIOPT Version :9

• Sequence 1: NP_001246966.1
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_598721.1
• Gene: Ces2a / 102022
• MGIID: 2142491
• Length: 558
• Species: Mus musculus
• Alignment Length: 559
• Identity: 173/559 - (30%)
• Similarity: 273/559 - (48%)
• Gaps: 71/559 - (12%)

  Fly   181 VDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLPPVCPQKLPDLSPHGSENMSRARHKHLS 245
            |..|||:|:|:.|.|..||.||..|.||.|::.....|.:|.|  ||:.     |:..|  |.::
Mouse    55 VHAFLGIPFAKPPVGLLRFAPPEDPEPWSGVRDGTSQPAMCLQ--PDIM-----NLEDA--KEMN 110

  Fly   246 RLLPYLRTESEDCLYLNLYVP-H-EEPQSTPKQYAVLVYLHGESFEWNSGNPYDGSVLSSYGEVI 308
            .:||.: :.||||||||:|.| | :|..:.|    |:|::||......|.:..|.|.|::..|::
Mouse   111 LILPPI-SMSEDCLYLNIYTPTHAQEGSNLP----VMVWIHGGGLVVGSASMNDVSKLAATEEIV 170

  Fly   309 VVTVNYRLGVLGFLRPSIDAHNIANYALLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACVN 373
            :|.:.||||||||.... |.|...|:..|||:|||.|:::||..|||:..|||:.|.|.|...|:
Mouse   171 IVAIQYRLGVLGFFSTG-DQHARGNWGYLDQVAALRWVQKNIAYFGGNRDRVTIFGVSAGGTSVS 234

  Fly   374 YLMVSPVASGLFHRAILMSGSAMSDWAASNQSLQLTMQIAHALECPLNEHVEAEDDDVLLDCLRH 438
            ..::||::.||||.||:.||.|:.....|:.|..:...:|:...|      ||.|.:.|:.|||.
Mouse   235 SHILSPMSKGLFHGAIMQSGVALLPDLISDTSEVVYKTVANLSGC------EATDSEALIHCLRA 293

  Fly   439 RRYQDILHIPTALTQFSTSLGPIVDGHVIPNQPYKVMGHYTEHFSRYDLLFGITESE-SYHTLAA 502
            :..|:||    |:.|....:..:|||..:|..|.:::  .:..|.....:.|:...| .:.....
Mouse   294 KSKQEIL----AINQVFKMIPAVVDGEFLPKHPQELL--TSMDFHPVPSIIGVNTDECGWGVPMF 352

  Fly   503 LALEEGLRENERDNLLRFYMQ--SRFDIRPDLALAATLKKYQDMYNNPIKATNLEHRDVVLDILS 565
            :.|:..::...|:.|......  :|..:.|:.: ...:::|.....:| :....:.|    ::|.
Mouse   353 MGLDHIIKNITRETLPAVLKNTAARMMLPPECS-HLLVEEYMGDTEDP-ETLQAQFR----EMLG 411

  Fly   566 DARVVGPLLQTGMF---HADVNRRNYMYVFGHNSATGPFAHLPHSIM----GEELAFIFGAPLAA 623
            |...|.|.||...|   .|.|    |.|.|.|.|:.  ..|:..|.:    |:::||:||:.|..
Mouse   412 DFMFVIPALQVAHFQRSQAPV----YFYEFQHLSSF--IKHVRPSHVKADHGDDVAFVFGSYLWD 470

  Fly   624 AGPFPSGNYTVQEKLLSEAVMAYWTNFVKTGNPKAPWKGIFINSHALEWDRYDLDWPEFNRRAQA 688
            .    :.:.|.:|:||...:|.||.||.:.|||         ||..|.      .||..:...|
Mouse   471 M----NLDLTEEEELLKRMMMKYWANFARNGNP---------NSEGLP------SWPVLDHDEQ- 515

  Fly   689 YLNIGIPPTVGYKYRQIYMNFWNKELPDELNQIAAIQEQ 727
            ||.:...|.||...:...:.||.|.||.::.::...|::
Mouse   516 YLQLDTQPAVGRALKARRLQFWTKTLPQKIQELKGSQDK 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_001246966.1	COesterase	153..710	CDD:278561	167/540 (31%)
		Aes	<263..>408	CDD:223730	58/146 (40%)
Ces2a	NP_598721.1	COesterase	30..537	CDD:278561	167/540 (31%)
		Aes	<127..>230	CDD:223730	43/107 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810