Protein Alignment Nlg1 and bche

DIOPT Version :10

• Sequence 1: NP_731172.2
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: XP_002931610.1
• Gene: bche / 100495889
• XenbaseID: XB-GENE-980117
• Length: 602
• Species: Xenopus tropicalis
• Alignment Length: 605
• Identity: 188/605 - (31%)
• Similarity: 288/605 - (47%)
• Gaps: 93/605 - (15%)

  Fly   155 TQEIQVKQGRLMGITRRFQVTSGLRQVDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLPP 219
            |..:..|.|::.|:  :..|.||:  :..|||:||||.|.|:.||..|....||..:..|.....
 Frog    30 TDIVDTKYGKVTGV--QISVFSGI--ITAFLGIPYAEPPIGDLRFKKPVPHKPWSEIWNASQYGN 90

  Fly   220 VCPQKLPDLSP--HGSENMSRARHKHLSRLLPYLRTESEDCLYLNLYVPHEEPQSTPKQYAVLVY 282
            .|.|.:..:.|  .|:|..:           |..:. ||||||||:::|..:|::.    :|:|:
 Frog    91 SCYQTVDQIFPGFSGAEMWN-----------PNTQL-SEDCLYLNIWIPTPKPRNA----SVMVW 139

  Fly   283 LHGESFE--WNSGNPYDGSVLSSYGEVIVVTVNYRLGVLGFLRPSIDAHNIA--NYALLDQIAAL 343
            ::|.|||  .:|.:.|||..|:....||||::|||||.||||  :...:|.|  |..|.||..||
 Frog   140 IYGGSFETGTSSLDLYDGKFLARTERVIVVSMNYRLGALGFL--AFPGNNEAPGNVGLFDQRLAL 202

  Fly   344 HWIKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASGLFHRAILMSGSAMSDWA------AS 402
            .|:.|||.||||:...:|:.|.|.|.|.|:|.|:||.:.|.|.|||:.|.:|.:.||      ||
 Frog   203 QWVYENIAAFGGNPKSITIFGESAGGASVSYHMLSPKSHGFFTRAIMQSATANAPWAVITKAEAS 267

  Fly   403 NQSLQLTMQIAHALECPLNEHVEAEDDDVLLDCLRHRRYQDILHIPTAL----TQFSTSLGPIVD 463
            |::|.|    |:.|.|......|      ::.|||::..::|.....::    :....:..|.||
 Frog   268 NRALTL----ANLLNCFYRNETE------IIACLRNKSPEEIFEKAVSVLPHRSVIEVNFPPTVD 322

  Fly   464 GHVIPNQPYKVMGHYTEHFSRYDLLFGITESESYHTLAALALEEGLRENERD-----NLLRFY-- 521
            |..:...| :::....:...:..:|.|:.:.|..:.|.     .||....:|     |..:|:
 Frog   323 GDFLIEMP-EILMQLGQLKKKTQILTGVNKDEGSYFLV-----YGLPGFSKDHESFINRTQFHKS 381

  Fly   522 MQSRFDIRPDLALAATLKKYQDMYN--NPIKATNLEHRDVVLDILSDARVVGPLLQTGMFHADVN 584
            ::..|....:||:.:.|..|.:..:  ||     ..:||.:.||:.|...:.|||:...:::::.
 Frog   382 VKLAFPKATELAIDSVLFHYTNWEDEQNP-----SHNRDAMDDIVGDYNFICPLLEFTKWNSELG 441

  Fly   585 RRNYMYVFGHNSA--TGP-FAHLPHSIMGEELAFIFGAPLAAAGPFPSGNYTVQEKLLSEAVMAY 646
            ...|:|.|.|.|:  |.| :..:.|   |.|:.|:||.|:     :...|||..|:.||..:|.|
 Frog   442 NNAYLYYFHHRSSKLTWPGWMGVMH---GYEIEFVFGIPM-----YRRLNYTKAEETLSRTLMRY 498

  Fly   647 WTNFVKTGNPKAPWKGIFINSHALEWDRYDLDWPEFNRRAQAYLNIGIPPT-VGYKYRQIYMNFW 710
            |.||.|||||         |......:|    ||.|....|.||.:|...: ...|.|.....||
 Frog   499 WANFAKTGNP---------NGAQSSENR----WPVFTLDEQHYLMLGTEDSKTNRKMRAKQCRFW 550

  Fly   711 NKELPDELNQIAAIQEQLQK 730
            |...|..|.....|.|..|:
 Frog   551 NNFYPKVLQITGNIDEVEQQ 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_731172.2	COesterase	157..710	CDD:395084	179/581 (31%)
bche	XP_002931610.1	COesterase	32..550	CDD:395084	179/581 (31%)
		AChE_tetra	565..599	CDD:430146	2/6 (33%)