Protein Alignment Nlg1 and ache

DIOPT Version :9

• Sequence 1: NP_001246966.1
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: XP_002940088.1
• Gene: ache / 100490673
• XenbaseID: XB-GENE-923160
• Length: 600
• Species: Xenopus tropicalis
• Alignment Length: 595
• Identity: 185/595 - (31%)
• Similarity: 269/595 - (45%)
• Gaps: 87/595 - (14%)

  Fly   163 GRLMGITRRFQVTSGLRQ------VDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLPPVC 221
            |.|:..||..:| .||||      |..|||:|:||.|....||.......||..:..|...|..|
 Frog    27 GGLLVSTRSGKV-RGLRQPVLSTHVSAFLGIPFAEPPVDKMRFRRSEPKKPWTDVWDATAYPNAC 90

  Fly   222 PQKLPDLSPHGSENMSRARHKHLSRLLPYLRTESEDCLYLNLYVPHEEPQSTPKQYAVLVYLHGE 286
            .|....|.| |...|......         |..||||||||::|||..|.:.    .|:|:::|.
 Frog    91 YQYFDTLYP-GFPGMEMWNPN---------RPMSEDCLYLNIWVPHPRPSNA----TVMVWIYGG 141

  Fly   287 SFEWNSG--NPYDGSVLSSYGEVIVVTVNYRLGVLGFLR---PSIDAHNIANYALLDQIAALHWI 346
            .|...|.  :.|||..|.....||||::|||:|..|||.   .|:||.  .|..|.||..||.|:
 Frog   142 GFYSGSSSLDVYDGRYLCHAENVIVVSMNYRVGAFGFLTLTPGSVDAP--GNVGLFDQRLALQWV 204

  Fly   347 KENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASGLFHRAILMSGSAMSDWA--ASNQSLQLT 409
            ::||..||||...||:.|.|.||..|...::||.:..||.:|.|.|||..:.||  ...::.:.|
 Frog   205 QDNIAFFGGDPRTVTIFGESAGAVSVGMHVLSPGSHHLFSKAALQSGSPNTPWATITPQEARRRT 269

  Fly   410 MQIAHALECPLNEHVEAEDDDVLLDCLRHRRYQDIL----HIPTALTQFSTSLGPIVDGHVIPNQ 470
            ..:...|:|.:.      :|..||:|||.::.|:::    .:..|.:.|..:..|:.|....|..
 Frog   270 ELLGKFLDCRMG------NDTELLNCLRVKQPQELIDHEFSVLPAPSVFRFAFVPVPDADFFPEP 328

  Fly   471 PYKVMGHYTEHFSRYDLLFGITESE-SYHTLAALALEEGLRENERDNLLR--FYMQSRFDI--RP 530
            |..:|.  ...|....|:.|:.::| ||..|..   ..|..:|....:.|  |....:..:  ..
 Frog   329 PEILMN--MGRFKPCPLIMGVNQNEGSYFLLYG---APGFSKNNESLITREEFLGGVKMSVPQAN 388

  Fly   531 DLALAATLKKYQDMYNNPIKATNLEHRDVVLDILSDARVVGPLLQTGMFHADVNRRNYMYVFGH- 594
            |:||.|.:.:|.|..:   :...:::|:.:..::.|..|:.||.......|:...|.|.|.|.|
 Frog   389 DIALEAVVMQYTDWAD---EHAGVKNREAMDQLVGDHNVICPLTYFAGKVAETGNRVYTYFFDHR 450

  Fly   595 --NSATGPFAHLPHSIMGEELAFIFGAPLAAAGPFPSGNYTVQEKLLSEAVMAYWTNFVKTGNPK 657
              |.|...:..:||   |.|:.|:||.||.|     :.|||.||:.||..:|.||.||.:||:|.
 Frog   451 ASNLAWPQWMGVPH---GYEIEFVFGLPLDA-----NLNYTPQEEALSRRMMRYWANFARTGDPN 507

  Fly   658 APWKGIFINSHALEWDRYDLDWPEFNRRAQAYLNIGIPPTVGYKYRQIY------MNFWNKELPD 716
               :|.         |.:...||.:....|.|:.:...|     |:::.      ..|||:.||.
 Frog   508 ---EGN---------DAHQPRWPLYTASEQRYMALNNKP-----YQELQGIRVQTCMFWNRFLPK 555

  Fly   717 ELNQIAAIQE 726
            .||....|.|
 Frog   556 LLNITDNIDE 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_001246966.1	COesterase	153..710	CDD:278561	176/577 (31%)
		Aes	<263..>408	CDD:223730	58/151 (38%)
ache	XP_002940088.1	COesterase	31..549	CDD:395084	174/573 (30%)
		AChE_tetra	564..597	CDD:400834	1/2 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910