Protein Alignment Nlg1 and nlgn4x

DIOPT Version :9

• Sequence 1: NP_001246966.1
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: XP_017946613.1
• Gene: nlgn4x / 100329189
• XenbaseID: XB-GENE-6036018
• Length: 833
• Species: Xenopus tropicalis
• Alignment Length: 854
• Identity: 242/854 - (28%)
• Similarity: 378/854 - (44%)
• Gaps: 196/854 - (22%)

  Fly   141 HPERRHVVPDKLQYTQEIQVKQGRLMGITRRFQVTSGLRQVDQFLGLPYAEAPTGNRRFMPPGAP 205
            ||    :||          ...|::.| ||.......|..|:|:||:|||..|||.|||.||..|
 Frog    45 HP----IVP----------TNYGKIRG-TRTPLPIEILGPVEQYLGVPYASPPTGERRFQPPEPP 94

  Fly   206 LPWQGLKIARHLPPVCPQKLPDLSPHGSENMSRARHKHLSRLLP------------YLRTESEDC 258
            ..|.|:|.|....|||||.|.:.|             .|:.:||            |::.::|||
 Frog    95 SSWTGIKNATQFAPVCPQFLDERS-------------LLNDMLPIWFTANLDTVVSYVQDQNEDC 146

  Fly   259 LYLNLYVPHEEPQSTPKQ---------------------YAVLVYLHGESFEWNSGNPYDGSVLS 302
            ||||:|||.|:..:|.||                     ..|:||:||.|:...:||..|||:|:
 Frog   147 LYLNIYVPTEDGATTKKQADDIANNDRGEDEDIHDPNNKKPVMVYIHGGSYMEGTGNMIDGSILA 211

  Fly   303 SYGEVIVVTVNYRLGVLGFLRPSIDAHNIANYALLDQIAALHWIKENIEAFGGDNSRVTLMGHST 367
            |:|.|||:||||||||||||.....|.. .||.|||||.||.||:|||.|||||..|||:.|...
 Frog   212 SHGNVIVITVNYRLGVLGFLSTGDQAAK-GNYGLLDQIQALRWIEENIGAFGGDPKRVTIFGSGA 275

  Fly   368 GAACVNYLMVSPVASGLFHRAILMSGSAMSDWAASNQSLQLTMQIAHALECPLNEHVEAEDDDVL 432
            ||:||:.|.:|..:.|||.:||:.||:|:|.||.:.|..:.|..:|..:.|.:.:.::      |
 Frog   276 GASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCDMLDTID------L 334

  Fly   433 LDCLRHRRYQDILHIPTALTQFSTSLGPIVDGHVIPNQPYKVMGHYTEHFSRYDLLFGITESESY 497
            ::|||.:.|::::........:..:.||::||.|||:.|..:|..  ..|..||::.|:.:.|
 Frog   335 VECLRDKNYKELIQQSITPATYHIAFGPVIDGDVIPDDPQILMEQ--GEFLNYDIMLGVNQGE-- 395

  Fly   498 HTLAALALEEGLRENER---------------DNLLRFYMQSRFDIRPDLALAATLKKYQDMYNN 547
                .|...:|:.:||.               |||.. |.:.:..:|..:..         ||.:
 Frog   396 ----GLKFVDGMVDNEDGVSLSDFDFSVSNFVDNLYG-YPEGKDTLRETIKF---------MYTD 446

  Fly   548 PIKATNLE-HRDVVLDILSDARVVGPLLQTGMFHADVNRRNYMYVFGHNSATGPFAHLPHSIMGE 611
            .....|.| .|..::.:.:|.:.|.|.:.|...||......|.|.|.|:..:........|..|:
 Frog   447 WADKENPETRRKTLVALFTDHQWVAPAVATADLHARYGSPTYFYAFYHHCQSEMKPTWADSAHGD 511

  Fly   612 ELAFIFGAPLAAAGPFPSGNYTVQEKLLSEAVMAYWTNFVKTGNPKAP----WKGIFINSHALEW 672
            |:.::||.|:.......:.|::..:.:||..||.|||||.|||:|..|    .|.|....:..|
 Frog   512 EVPYVFGIPMIGPTELFNCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKPNRFE- 575

  Fly   673 DRYDLDWPEFNRRAQAYLNIGIPPTVGYKYRQIYMNFWNKELP-----DELNQIAAIQEQLQKPG 732
               ::.|.:::.:.|.||:||:.|.|...||...:.||.:.:|     :|:.|..:...::..|
 Frog   576 ---EVAWSKYDPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNLNEIFQYVSTTTKVPPP- 636

  Fly   733 QEVITGHMSKYGPRDHGAEDPVRTLKLLLQEPSLAGPTQSGESTETAAENMYNAPPTFGHVHKMQ 797
                  .|:.|   .|....|....::..:.|::. |..:.:.|:   :|:
 Frog   637 ------DMTSY---PHVTRRPPLKPRITTKRPAMT-PANNAKETQ---KNV-------------- 674

  Fly   798 GGSDFEDLVTSTNSLESGEDHPQAPPETVAKSEATMQLLIALITIIIVLNLLIYGTFLLRQRRRR 862
                   |..:|...|...|:           ...:.:.||:...::.||:|.:.....::.:||
 Frog   675 -------LGENTIITEDKRDY-----------STELSVTIAVGASLLFLNILAFAALYYKKDKRR 721

  Fly   863 AKALPFPAPKLGGTILSYDGAND------EELKRCSKSRDGDDSFVLEMTRKSNTYEAIKTGQRS 921
            .:....|:|:...|       ||      ||:            ..|:|.:..:.:|
 Frog   722 HETHRRPSPQRNTT-------NDIAHIQNEEI------------MSLQMKQLEHDHE-------- 759

  Fly   922 LSCSTVDTH 930
              |..:..|
 Frog   760 --CEALQAH 766

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_001246966.1	COesterase	153..710	CDD:278561	201/609 (33%)
		Aes	<263..>408	CDD:223730	78/165 (47%)
nlgn4x	XP_017946613.1	COesterase	46..610	CDD:365897	204/620 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D80457at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43903
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020