Protein Alignment Nlg1 and nlgn2

DIOPT Version :9

• Sequence 1: NP_001246966.1
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: XP_031755501.1
• Gene: nlgn2 / 100329187
• XenbaseID: XB-GENE-6034906
• Length: 810
• Species: Xenopus tropicalis
• Alignment Length: 860
• Identity: 249/860 - (28%)
• Similarity: 384/860 - (44%)
• Gaps: 171/860 - (19%)

  Fly   158 IQVKQGRLMGITRRFQVTSGLRQVDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLPPVCP 222
            :....|:|.|:.:... ...|..|.|:||:|||..|.|.|||..|.||..|..::.|....||||
 Frog    31 VNTNYGKLRGVKKDLN-NEILGPVVQYLGIPYATPPIGERRFQAPEAPASWTEVRNATTFAPVCP 94

  Fly   223 QKLPDLSPHG-------SENMSRARHKHLSRLLPYLRTESEDCLYLNLYVP---------HEEP- 270
            |.|..:.| |       :|||        ..:..|::.:||||||||:|||         .|:|
 Frog    95 QNLHGMLP-GIMLPLWFTENM--------DVVAGYVQNQSEDCLYLNIYVPLEDGPISKSREDPR 150

  Fly   271 --QSTPKQ-------YAVLVYLHGESFEWNSGNPYDGSVLSSYGEVIVVTVNYRLGVLGFLRPSI 326
              |.||.:       ..|::::||.|:...:||.:|||||::||.|||||:|||||:|||:....
 Frog   151 KAQHTPDEDIRDSGKKPVMMFIHGGSYMEGTGNMFDGSVLAAYGNVIVVTLNYRLGILGFMSTGD 215

  Fly   327 DAHNIANYALLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASGLFHRAILM 391
            .|.. .||.|||||.||.|::|||..||||..|:|:.|...||:||:.|::|..:.|||.:||..
 Frog   216 QAAK-GNYGLLDQIQALRWLEENIGHFGGDPERITIFGSGAGASCVSLLILSHHSEGLFQKAIAQ 279

  Fly   392 SGSAMSDWAASNQSLQLTMQIAHALECPLNEHVEAEDDDVLLDCLRHRRYQDILHIPTALTQFST 456
            ||:|:|.|:.:.:.|:.|..:|..:.|...|:.|      ::.|||.:.|:|::.......::..
 Frog   280 SGTAISSWSVNYEPLKYTRLLAAKVGCDYQENSE------MVMCLRRKPYRDLVDQDIQPARYHI 338

  Fly   457 SLGPIVDGHVIPNQPYKVMGHYTEHFSRYDLLFGITESESYHTLA-ALALEEGLR--------EN 512
            :.||:|||.|:|:.|..:|..  ..|..||:|.|:.:.|....:. .|..|:|:.        .|
 Frog   339 AFGPVVDGDVVPDDPEILMEQ--GEFLNYDILMGVNQGEGLKFVEDTLESEDGISNSYFDFTVSN 401

  Fly   513 ERDNLLRFYMQSRFDIRPDLALAATLKKYQDMYNNPIKATNLEHRDVVLDILSDARVVGPLLQTG 577
            ..|||..| .:.:..:|..:....|  .:.|..|..::      |..:|.:.:|.:.|.|.:.|.
 Frog   402 FVDNLYGF-AEGKDVLRETIKFMYT--DWADRDNGDMR------RKTLLALFTDHQWVAPAIATA 457

  Fly   578 MFHADVNRRNYMYVFGHNSAT------GPFAHLPHSIMGEELAFIFGAPLAAAGPFPSGNYTVQE 636
            .|||:.....|.|.|.|....      |..||      |:|:.::||.|:..|......|::..:
 Frog   458 KFHAEYESPVYFYAFYHRCQAEGRPEWGEAAH------GDEVPYVFGVPMVGATDLFPCNFSKND 516

  Fly   637 KLLSEAVMAYWTNFVKTGNPKAP----WKGIFINSHALEWDRYDLDWPEFNRRAQAYLNIGIPPT 697
            .:||..||.|||||.|||:|..|    .|.|....:..|    ::.|.:||.:.:.||:||:.|.
 Frog   517 VMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFE----EVVWTKFNPKEKQYLHIGLKPR 577

  Fly   698 VGYKYRQIYMNFWNKELP--DELNQIAAIQEQLQKPGQEVITG-HMSKYGPRDHGAEDPVRTLKL 759
            |...||...:.||.:.:|  .|||                 || |.|                 .
 Frog   578 VKDNYRANKVAFWLELVPHLHELN-----------------TGLHTS-----------------T 608

  Fly   760 LLQEPSLAGPTQSGESTETAAENMYNAPPTFGHVHKMQGGSDFEDLVTSTNSLESGEDHPQAPPE 824
            ..::|:  |.|:...|..|........||..          |.|         |..::.|:..|.
 Frog   609 TTRQPT--GGTRRTSSGSTTRRPPVTFPPDI----------DIE---------EEMDNRPRYSPF 652

  Fly   825 TVAKSEATMQL--LIALITIIIVLNLLIYGTFLLRQRRRRAKALPFPAPKLG---GTILSYDGAN 884
            .....:.:.:|  .:|:...::.||:|.:.....::.||........:|..|   |..|::.|..
 Frog   653 PGDSRDYSTELSVTVAVGASLLFLNILAFAALYYKRDRRHELRQRRHSPGRGGVPGNDLAHHGPE 717

  Fly   885 DE----ELKRCSKSRDGDDSFVLEMTRKSNTYEAIKTGQRSLSCSTVDTHTKVCEWMSSQEAPKS 945
            :|    ::||...:.|      ||..|..:....        :|....|       ::.:.||:.
 Frog   718 EELMSLQIKRAGGAPD------LEPLRPHDILRP--------ACPPDYT-------LALRRAPED 761

  Fly   946 GSFNTATPPPQPILS 960
            .......|||..:::
 Frog   762 APLPPPPPPPTSVMA 776

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_001246966.1	COesterase	153..710	CDD:278561	201/596 (34%)
		Aes	<263..>408	CDD:223730	72/163 (44%)
nlgn2	XP_031755501.1	COesterase	29..590	CDD:395084	201/596 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D80457at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010