Protein Alignment Nlg1 and cel.2

DIOPT Version :9

• Sequence 1: NP_001246966.1
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_001120027.1
• Gene: cel.2 / 100144991
• XenbaseID: XB-GENE-1217488
• Length: 552
• Species: Xenopus tropicalis
• Alignment Length: 570
• Identity: 157/570 - (27%)
• Similarity: 235/570 - (41%)
• Gaps: 125/570 - (21%)

  Fly   181 VDQFLGLPYAEAPTG-NRRFMPPGAPLPWQGLKIARHLPPVCPQKLPDLSPHGSENMSRARHKHL 244
            :|.|.|:|:|..|.. .:....||    |.|...|:...|.|.|     :....:|:
 Frog    47 IDIFKGIPFAAPPKPFEKAEKHPG----WSGTLQAKDYKPRCLQ-----ATITQDNV-------- 94

  Fly   245 SRLLPYLRTESEDCLYLNLYVPHEEPQ-STPKQYAVLVYLHGESFEWNSGNP--------YDGSV 300
                    ..|.||||||::||....| ||  ...|:|::.|..|...||..        |||..
 Frog    95 --------FGSLDCLYLNVWVPQTRSQVST--NLPVMVWIFGGGFLLGSGQGANFLSNYLYDGEE 149

  Fly   301 LSSYGEVIVVTVNYRLGVLGFLRPSIDAHNIANYALLDQIAALHWIKENIEAFGGDNSRVTLMGH 365
            ::..|:|||||.|||:|.||||... |::...||.|.||..|:.|:|.||.|||||.:.:||.|.
 Frog   150 VAMRGKVIVVTFNYRVGPLGFLSTG-DSNAPGNYGLWDQHMAIAWVKRNIAAFGGDPNNITLFGE 213

  Fly   366 STGAACVNYLMVSPVASGLFHRAILMSGSAMSDWAASNQSLQLTMQIAHALECPLNEHVEAEDDD 430
            |.|.|.|:...::|...||..|||..||..:..||.....|.....:|..|.||:|...|
 Frog   214 SAGGASVSLQTLTPYNVGLIKRAISQSGVGLCPWAIQRDPLTWAKSLASKLGCPVNNTKE----- 273

  Fly   431 VLLDCLRHR-------RYQ-DILHIPTALTQFSTSLGPIVDGHVIPNQPYKVM------------ 475
             |.||||:.       .|| .:.::...|..: .:..|::||..||::|..:.
 Frog   274 -LADCLRNTDPGALTIAYQLQLFNLEYPLVHY-LAYSPVIDGDFIPDEPRNLFSNAAGVDYIAGV 336

  Fly   476 ----GHYTEHFSRYDL------LFGITESESYHTLAALALEEGLRENERDNLLRFYMQSRFDIRP 530
                ||.   |:..||      |..|:..:....:..|.|.:|:              ...||..
 Frog   337 NNMDGHL---FAGVDLPAINQPLHKISTEQVQKVVRGLTLAKGV--------------PALDIAY 384

  Fly   531 DLALA--ATLKKYQDMYNNPIKATNLEHRDVVLDILSDARVVGPLLQTGMFHADVNRRNYMYVFG 593
            ||..|  .|....:||     |.|.:|.....:.:::....:....|...     ..:.|.|:|.
 Frog   385 DLYTAGWGTNPSQEDM-----KRTVVEVETDYIFLVATQEALALHYQNAK-----GAKTYSYMFS 439

  Fly   594 HNSATGPFAHLPHSIMGEELAFIFGAPLAAAGPFPSGNYTVQEKLLSEAVMAYWTNFVKTGNPK- 657
            |.|....:.....:...|:|.|:||.|.:.  |..   |..:::.:::.::||||||..||:|.
 Frog   440 HPSRMPVYPSWMGADHAEDLQFMFGKPFST--PLA---YRPRDRDVAQYMIAYWTNFAATGDPSK 499

  Fly   658 ------APW------KGIFIN-SHALEWD--RYDLDWPEFNRRAQAYLNI 692
                  .||      .|.::. :|.:.:.  :..|..|.....||.::|:
 Frog   500 GESSIPTPWLAYSTENGQYLEINHKINYQSMKQSLRSPYVRFWAQTFINL 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_001246966.1	COesterase	153..710	CDD:278561	157/570 (28%)
		Aes	<263..>408	CDD:223730	62/153 (41%)
cel.2	NP_001120027.1	COesterase	24..542	CDD:365897	154/561 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43903
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.100