Protein Alignment Nlg1 and ces3.1

DIOPT Version :9

• Sequence 1: NP_001246966.1
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_001120019.1
• Gene: ces3.1 / 100144981
• XenbaseID: XB-GENE-6467140
• Length: 557
• Species: Xenopus tropicalis
• Alignment Length: 599
• Identity: 171/599 - (28%)
• Similarity: 274/599 - (45%)
• Gaps: 101/599 - (16%)

  Fly   158 IQVKQGRLMGITRRFQVTSGLRQVDQ----FLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLP 218
            :..|.|:|:|      .|.|.::.|:    |:|:|:|:.|.|..||..|..|.||..::.|....
 Frog    27 LMTKYGQLLG------KTVGAKETDRLVHVFMGVPFAKPPIGPLRFEAPQPPEPWSSVREATAPS 85

  Fly   219 PVCPQKLPDLSPHGSENMSRARHKHLSRLL-PYLRTE------SEDCLYLNLYVPHEEPQSTPKQ 276
            |:|.|                 .|.:..|| .:.:.:      ||||||||::.|.::.::  ..
 Frog    86 PMCLQ-----------------DKEVMELLADFFKAKFDFSRVSEDCLYLNVFTPADKGEN--PG 131

  Fly   277 YAVLVYLHGESFEWNSGNPYDGSVLSSYGEVIVVTVNYRLGVLGFLRPSIDAHNIANYALLDQIA 341
            ..|:|::||........:.::||.||:|..|:||::.||||::|||... |.....|:..|||:|
 Frog   132 LPVMVFIHGGGLAIGGASMFEGSALSAYENVVVVSIQYRLGIMGFLSTG-DKEVRGNFGFLDQVA 195

  Fly   342 ALHWIKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASGLFHRAILMSGSAMSDWAASNQS- 405
            ||.|:::||:.||||...||:.|.|.|...|:.|::||::.|||||||..||.|:.....::::
 Frog   196 ALQWVRDNIKDFGGDPQSVTIFGESAGGLSVSALVLSPLSEGLFHRAIAESGVAILPGLTASKTE 260

  Fly   406 --LQLTMQIAHALECPLNEHVEAEDDDVLLDCLRHRRYQDILHIPTALTQFSTSLGPIVDGHVIP 468
              |.|...:.:...|.:::         |:.||:::...:|:.|..|:..  .....:|||..:|
 Frog   261 EILPLLDMVINVSSCSVSD---------LVGCLKNKTEDEIIEITAAMRY--VIFPAVVDGVFLP 314

  Fly   469 NQPYKVMGHYTEHFSRYDLLFGITESESYH----TLAALALEEGLRENERDNLLRFYMQSRFDIR 529
            ....:::.....|  ....|.||...|...    ||......||:.:.:        :|:.....
 Frog   315 KPAEEILAAKESH--PVPFLIGINNHEFGSMLPVTLNITGYREGMEKKD--------IQAILGAL 369

  Fly   530 PDLALAAT-----LKKYQDMYNNPIKATNLEHRDVVLDILSDARVVGPLLQTGMFHADVNRRNYM 589
            |.|...::     :::|....|:|     .|.|:..||:..|...|.|.|:|..:|.|.....|.
 Frog   370 PLLNTVSSVIPFIMEEYFGDTNDP-----KELRNNFLDLAGDIIFVIPALRTAKYHRDSGFPVYF 429

  Fly   590 YVFGHN-----SATGPFAHLPHSIMGEELAFIFGAPLAAAGPFPSGNYTVQEKLLSEAVMAYWTN 649
            |.|.|.     .:...|....|   |:||.|:.|.|....|.....|.|.:||:||:.:|.||.|
 Frog   430 YEFQHRPSLYADSKEDFVKADH---GDELYFVGGGPFLKNGILFKSNGTEEEKILSKTIMKYWAN 491

  Fly   650 FVKTGNPKAPWKGIFINSHAL-EWDRYDLDWPEFNRRAQAYLNIGIPPTVGYKYRQIYMNFWNKE 713
            |.:.|:|         |.|.| ||.:||.|        :.||.|.:......:.:.....||...
 Frog   492 FARNGDP---------NGHGLAEWPKYDED--------EDYLEINLTQKSSQRLKGERFEFWTIT 539

  Fly   714 LPDELNQIAAIQEQ 727
            |||::.::...:||
 Frog   540 LPDKIQKLMEEKEQ 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_001246966.1	COesterase	153..710	CDD:278561	164/580 (28%)
		Aes	<263..>408	CDD:223730	55/147 (37%)
ces3.1	NP_001120019.1	COesterase	25..536	CDD:365897	164/580 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910