Protein Alignment Nlg1 and Ces1f

DIOPT Version :9

• Sequence 1: NP_001246966.1
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_001096829.2
• Gene: Ces1f / 100125372
• RGDID: 1642419
• Length: 561
• Species: Rattus norvegicus
• Alignment Length: 589
• Identity: 167/589 - (28%)
• Similarity: 266/589 - (45%)
• Gaps: 97/589 - (16%)

  Fly   158 IQVKQGRLMGITRRFQVTSGLRQ-VDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLPPVC 221
            :...:|:::|   ::....|:.| |..|||:|:|:.|.|:.||.||....||..:|.....||:|
  Rat    26 VDTTKGKVLG---KYVSLEGVTQSVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTTYPPMC 87

  Fly   222 P------QKLPDLSPHGSENMSRARHKHLSRLLPYLRTESEDCLYLNLYVPHEEPQSTPKQYAVL 280
            .      |::.||..:..|.:      ||.        .||||||||:|.|.:..:::  :..|:
  Rat    88 SQDAAKGQRMNDLLTNRKEKI------HLE--------FSEDCLYLNIYTPADFTKNS--RLPVM 136

  Fly   281 VYLHGESFEWNSGNPYDGSVLSSYGEVIVVTVNYRLGVLGFLRPSIDAHNIANYALLDQIAALHW 345
            |::||........:.|||.|||:|..|:||.:.||||:.||.... |.|:..|:..|||:|||||
  Rat   137 VWIHGGGMTLGGASTYDGRVLSAYENVVVVAIQYRLGIWGFFSTG-DEHSRGNWGHLDQVAALHW 200

  Fly   346 IKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASGLFHRAILMSGSAMSDWAASNQSLQLTM 410
            :::||..||||...||:.|.|.|...|:.|::||:...||||||..||........:........
  Rat   201 VQDNIANFGGDPGSVTIFGESAGGFSVSVLVLSPLTKNLFHRAISESGVVFLPGLLTKDVRPAAK 265

  Fly   411 QIAHALECPLNEHVEAEDDDVLLDCLRHRRYQDILHIPTALTQFSTS-----------LGPIVDG 464
            |||....|      |.....:::.|||.:..:::|.|...:.....|           |..:||.
  Rat   266 QIADMAGC------ETTTSAIIVHCLRQKTEEELLEIMKKMNLIKLSSQRDNKESYHFLSTVVDN 324

  Fly   465 HVIPNQPYKVMGHYTEHFSRYDLLFGITESESYHTLAALALEEGL--RENERDNLLRFYMQSRF- 526
            .|:|..|.:::..  ::|:....:.||.:.|....|..:.   |.  .:.|.|..:...:..:|
  Rat   325 VVLPKDPKEILAE--KNFNTVPYIVGINKQECGWLLPTMM---GFVPADVELDKKMAITLLEKFA 384

  Fly   527 -------DIRPDLALAATLKKYQDMYNNPIKATNLEHRDVVLDILSDARVVGPLLQTGMFHADVN 584
                   ||.|     ..::||:...::.||.     ||.:|..:.|.....|.:.....|.|..
  Rat   385 SLYGIPEDIIP-----VAIEKYRKGSDDSIKI-----RDGILAFIGDVSFSIPSVMVSRDHRDAG 439

  Fly   585 RRNYMYVFG-HNSATGPFAHLPHSIMG---EELAFIFGAPLAAAGPFPSGNYTVQEKLLSEAVMA 645
            ...|||.:. :.|.:.|  ..|..::|   ::|..:||||:...|.      :.:|..||:.||.
  Rat   440 APTYMYEYQYYPSFSSP--QRPKHVVGDHADDLYSVFGAPILRDGA------SEEEIKLSKMVMK 496

  Fly   646 YWTNFVKTGNPKAPWKGIFINSHALEWDRYDLDWPEFNRRAQAYLNIGIPPTVGYKYRQIYMNFW 710
            :|.||.:.|||         |...|.      .||::::: :.||.||.......:.:...:.||
  Rat   497 FWANFARNGNP---------NGRGLP------HWPQYDQK-EEYLQIGATTQQSQRLKAEEVAFW 545

  Fly   711 NKEL 714
            .:.|
  Rat   546 TQLL 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_001246966.1	COesterase	153..710	CDD:278561	164/583 (28%)
		Aes	<263..>408	CDD:223730	56/144 (39%)
Ces1f	NP_001096829.2	COesterase	24..545	CDD:278561	164/583 (28%)
		Aes	<121..>234	CDD:223730	46/115 (40%)
		Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138	558..561

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810