Protein Alignment Nlg1 and nlgn2b

DIOPT Version :10

• Sequence 1: NP_731172.2
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_001159808.1
• Gene: nlgn2b / 100002407
• ZFINID: ZDB-GENE-090918-3
• Length: 860
• Species: Danio rerio
• Alignment Length: 900
• Identity: 254/900 - (28%)
• Similarity: 387/900 - (43%)
• Gaps: 183/900 - (20%)

  Fly   137 STTHHPERRHVVPDKLQYTQEIQVKQGRLMGITRRFQVTSGLRQVDQFLGLPYAEAPTGNRRFMP 201
            :|..||              .:....|:|.|:.:... ...|..|:|:||:|||..|.|.|||.|
Zfish    47 TTAKHP--------------MVTTGYGKLRGVRKELN-NEILGPVEQYLGVPYATPPVGERRFQP 96

  Fly   202 PGAPLPWQGLKIARHLPPVCPQKLPDLSPH------GSENMSRARHKHLSRLLPYLRTESEDCLY 260
            |.||..||.::.|....|||||.:..:.|.      .::|:..|        ..|::.:||||||
Zfish    97 PEAPGSWQEIRNATQFAPVCPQNIHGVLPEIMLPVWFTDNLDAA--------AAYVQNQSEDCLY 153

  Fly   261 LNLYVPHEEPQSTPK------------------QYAVLVYLHGESFEWNSGNPYDGSVLSSYGEV 307
            ||:|||.|:...|.|                  :..|::::||.||...:||.:|.|||::||.|
Zfish   154 LNVYVPTEDGPLTKKHDESSMNRPRDEDIRDRRKKPVMLFIHGGSFMEGTGNMFDASVLAAYGNV 218

  Fly   308 IVVTVNYRLGVLGFLRPSIDAHNIANYALLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACV 372
            ||||:|||||||||| .|.|.....||.|||||.||.|:.|||..||||..|:|:.|...||:||
Zfish   219 IVVTMNYRLGVLGFL-SSGDQSAKGNYGLLDQIQALRWLNENIGHFGGDPERITIFGSGAGASCV 282

  Fly   373 NYLMVSPVASGLFHRAILMSGSAMSDWAASNQSLQLTMQIAHALECPLNEHVEAEDDDVLLDCLR 437
            |.|::|..:.|||.|||..||||:|.|:.:.:.|..|..:|..:.|..::..:      |:||||
Zfish   283 NLLILSHHSEGLFQRAIAQSGSAISSWSVNYRPLMYTKILAKKVGCSYSDTAD------LVDCLR 341

  Fly   438 HRRYQDILHIPTALTQFSTSLGPIVDGHVIPNQPYKVMGHYTEHFSRYDLLFGITESESYHTLAA 502
            .:.|::::.......::..:.||:|||.|:|:.|..:|  ....|..||:|.|:.:.|....:..
Zfish   342 RKSYRELVDQDVQPARYHIAFGPVVDGDVVPDDPEILM--QQGEFLNYDILLGVNQGEGLKFVDD 404

  Fly   503 LALEEGLR--------ENERDNLLRFYMQSRFDIRPDLALAATLKKYQDMYNNPIKATNLEHRDV 559
            ...|||:.        .|..|||.. |.:.:..:|..:....|  .:.|..|..::      |..
Zfish   405 NEGEEGISAASFDYTISNFVDNLYG-YPEGKDILRETIKFMYT--DWADRDNGDMR------RKT 460

  Fly   560 VLDILSDARVVGPLLQTGMFHADVNRRNYMYVFGHNSATGPFAHLPHSIMGEELAFIFGAPLAAA 624
            :|.:.:|.:.|.|.:.|...||:.....|.|.|.|:..|........:..|:|:.::||.|:..|
Zfish   461 LLALFTDHQWVAPAVATAKLHAEFQSPVYFYTFHHHCQTEARPEWADAAHGDEIPYVFGVPMVGA 525

  Fly   625 GPFPSGNYTVQEKLLSEAVMAYWTNFVKTGNPKAP----WKGIFINSHALEWDRYDLDWPEFNRR 685
            ......|::..:.:||..||.|||||.|||:|..|    .|.|....:..|    ::.|.:|:.:
Zfish   526 TELFPCNFSKNDIMLSAVVMTYWTNFAKTGDPNIPVPQDTKFIHTKPNRFE----EVIWTKFSSK 586

  Fly   686 AQAYLNIGIPPTVGYKYRQIYMNFWNKELPDELNQIAAIQEQLQKPGQEVITGHMSKYGPRDHGA 750
            .:.||:||:.|.:...||...:.||.:.:|                       |:       |..
Zfish   587 DKQYLHIGLKPRIRDNYRANKVAFWLELVP-----------------------HL-------HTI 621

  Fly   751 EDPVRTLKLLL-----QEPSLAGPTQSGESTETAAENMYNAPPTFGHVHKMQGGSDFEDLVTSTN 810
            .|.:.|....|     ..|...|..||..:..|....:...||          ..|.|
Zfish   622 HDEIPTYTTQLPPGAPHRPGWKGTAQSPGTRSTRHPTVSTYPP----------DPDLE------- 669

  Fly   811 SLESGEDHP--QAP-PETVAKSEATMQLLIALITIIIVLNLLIYGTF---------LLRQRRRRA 863
                |.:||  :.| |.........:.:.:|:...::.||:|.:...         ||::|.||.
Zfish   670 ----GSEHPPERFPFPSNTRDYSTELSVTVAVGASLLFLNVLAFAALYYKRDKRHELLQRRHRRL 730

  Fly   864 KALPFPAPKLGGTILSYDGAND------EELKRC----------------SKSRDGDDSFVLEMT 906
            .......|.:|  |:.....||      |||...                ::...||    ||..
Zfish   731 SPQRGAVPGVG--IVGGPPHNDLALSQEEELMSLQMKQQRVELDHGTPLPTRGLHGD----LEPL 789

  Fly   907 R----KSNTYEAIKTGQRSLSCSTVDTHTKVCEWMSSQEAPKSGSFNTATPPPQP 957
            |    ..:...|::.....:...|.:|.:.:...::..:  ...:|||..|.|.|
Zfish   790 RPPVCPPDYTLALRRAPEDVPLMTANTLSMIPSTITGMQ--PLHAFNTYPPAPAP 842

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_731172.2	COesterase	157..710	CDD:395084	198/588 (34%)
nlgn2b	NP_001159808.1	COesterase	52..611	CDD:395084	199/603 (33%)