Protein Alignment Nlg3 and Ces1h

DIOPT Version :9

• Sequence 1: NP_001036685.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_001357759.1
• Gene: Ces1h / 75704
• MGIID: 1922954
• Length: 562
• Species: Mus musculus
• Alignment Length: 666
• Identity: 175/666 - (26%)
• Similarity: 277/666 - (41%)
• Gaps: 163/666 - (24%)

  Fly   154 SSRIINTRNGAISGVIVQLDGRHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSP 218
            |..::||.:|.:.|..:.|:| ...||..:.|:|:|.||:|:|||.||.....||.||.|..:.|
Mouse    22 SPPVVNTTHGKVLGKYISLEG-FTQPVAVFLGVPFAKPPLGSLRFAPPQPPEPWSFVKNATSYPP 85

  Fly   219 VCPQR--LPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSS 281
            :|.|.  |..:.|: ..:....|.||.:           ||||||||:|.|:.:....:
Mouse    86 MCSQDAVLGQMVND-LIINNKEKIRLRF-----------SEDCLYLNVYTPVDLMKNTN------ 132

  Fly   282 SSAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASYGQI 346
                                             :.||:|::||........:.|||..|:::..:
Mouse   133 ---------------------------------RLPVMVWIHGGGLVVGGASAYDGRTLSAHENV 164

  Fly   347 LVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAA 411
            :||||.|||.:.||.:.. |.:|:  .|:|.:|.:|||||:::|||.|||||.|:|:.|...|..
Mouse   165 VVVTIQYRLAIWGFFSTG-DEHSR--GNWGHLDQLAALHWIQDNIANFGGDPGSVTIFGQSAGGE 226

  Fly   412 CVHFLISSMAVPEGLLFNRAILMSG----SGLAPWSLVSNPAKYAAIVAHHVNCASDLPHAHLMK 472
            .|..|:.|.....  ||:|||..||    |||    .:.:.:.....:|....|.: ...|.::.
Mouse   227 SVSVLVLSPLAKN--LFHRAISQSGVVFTSGL----FMEDASSVTEQIAVTAGCKT-TTSAVIVH 284

  Fly   473 CLREKTLDQLLSVPIRPPEF----------GFAFGPSI-DGVVIDGGDYVPPAPGSPAAQAQAQA 526
            |||:||.::||.:..:...|          .:.|.|:: ||||:      |.||.:..|:...
Mouse   285 CLRQKTEEELLEIMQKMNLFKLDAQENTKKNYPFLPTVLDGVVL------PKAPEAILAEKNF-- 341

  Fly   527 STAAGNGLGGEAGI-AAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAFFSFNSGDVQ 590
                 |.:....|| ....||..|..:|                              |...||:
Mouse   342 -----NTVPYIVGINKQEFGWTLPMIME------------------------------FPPTDVK 371

  Fly   591 YGIEADRRSRILKAYVRN-TYTFHLNEIFATIVNEYTDWERPVQHPINIRDETLEALSDAQVVAP 654
            ..      .:::..::|. .|.|::.|....:..|  .:.:....||..|...|:.:.|.....|
Mouse   372 LD------KKVISLFLRKLAYFFNIPEDGIPVAIE--KYSKGTDDPIQNRVWLLQLIGDVMFGIP 428

  Fly   655 AAQTVDLHSADHRN----SYLYVFDYQTRFGD--YPQRQGCIHGEDLPYIFGAPLVGGFNHFTRN 713
            :.    :.|..||:    :|:|.|..:..|..  .|:.....||:::..:||||::      ...
Mouse   429 SV----IVSRGHRDAGAPTYMYEFQSRPSFSSELKPKTVTGDHGDEVYSVFGAPIL------REG 483

  Fly   714 YTKTEISLSEVVMFYWSNFVRTGNPNEQMETEHGSRQERSRYKTIEWTAYESVHKKYLNFDTKPK 778
            .::.||:||:::|.:|:||.|.||||.| ...|             |..|.. .|.||......:
Mouse   484 SSEEEINLSKMMMKFWANFARNGNPNGQ-GLPH-------------WPEYNQ-KKGYLQIGATTQ 533

  Fly   779 LKNHYRAHRLSFWLNL 794
            .....:...:|.|..|
Mouse   534 QAQGLKDKEVSLWTEL 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_001036685.2	COesterase	151..791	CDD:278561	173/661 (26%)
		Aes	<313..>410	CDD:223730	39/96 (41%)
Ces1h	NP_001357759.1	COesterase	24..546	CDD:365897	172/659 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832416
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740