Protein Alignment Nlg3 and Ces2g

DIOPT Version :10

• Sequence 1: NP_731170.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_932116.2
• Gene: Ces2g / 72361
• MGIID: 1919611
• Length: 560
• Species: Mus musculus
• Alignment Length: 665
• Identity: 184/665 - (27%)
• Similarity: 286/665 - (43%)
• Gaps: 156/665 - (23%)

  Fly   154 SSRIINTRNGAISGVIVQLDGRHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSP 218
            :|.|.:|.:|.:.|.::.:...... |..:.|||:|.||||.|||.||.:...||||:.......
Mouse    32 TSPIRSTHSGQVQGRLIHVKDTKAG-VHTFLGIPFAKPPVGPLRFAPPEAPEPWSGVRDGTSQPA 95

  Fly   219 VCPQRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSSSS 283
            :|||      |.|..:|     .|:.||..||.: :.||||||||||.|
Mouse    96 ICPQ------NVTMNME-----GLKELKLTLPPV-SMSEDCLYLNIYTP---------------- 132

  Fly   284 AGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASYGQILV 348
                                  :.|..||  ..||:|::||.:......:.|||||||:...::|
Mouse   133 ----------------------AHAQEGS--NLPVMVWIHGGALTVGMASMYDGSVLAATEDVVV 173

  Fly   349 VTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAACV 413
            |.|.||||||||.:.. |.:::  .|:|.:|.:|||.|:::|||.|||:|:.:|:.|...|...|
Mouse   174 VAIQYRLGVLGFFSTG-DEHAR--GNWGFLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGISV 235

  Fly   414 -HFLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAKYAAIVAHHVNCASDLPHAHLMKCLREK 477
             ..::|.|:  :| ||:|||:.||..|.|.::.|........||....|.: :....|::|||.|
Mouse   236 SSHVVSPMS--KG-LFHRAIMESGVALLPGTIFSFSEVVYQTVAKLSGCEA-MDSEALVRCLRGK 296

  Fly   478 TLDQLLSVPIRPPEFGFAFGPSIDGVVIDGGDYVPPAPGSPAAQAQAQASTAAGNGLGGEAGIAA 542
            :.:::|::   ...|     ..|.|||  .|:::|..|....|.|......:.......|.
Mouse   297 SEEEILAI---SKNF-----QMIPGVV--DGEFLPKHPQELLASADFHPVPSIIGFNNDEY---- 347

  Fly   543 AGGWGTP---GQLENIVLMRKTAINKLSRYDLMAGVTRAEAFFSFNSGDVQYGIEADRRSRILKA 604
              ||..|   |..:.|                 .|:||..                      |:|
Mouse   348 --GWIVPKVIGSTQTI-----------------KGITREN----------------------LQA 371

  Fly   605 YVRNTYTFHL--NEIFATIVNEYTDWERPVQHPINIRDETLEALSDAQVVAPAAQTVDLHSADHR 667
            .:::|....:  .|....::.||.:   .::.|..::.:..|.:.|...|.|:.| |......|.
Mouse   372 VLKDTAPQMMLPPECSDLLMEEYME---DIEDPKTLQIQFTEMMEDFMFVIPSLQ-VAYFQRSHA 432

  Fly   668 NSYLYVFDYQTRF--GDYPQRQGCIHGEDLPYIFGAPLVGGFNHFTRNYTKTEISLSEVVMFYWS 730
            ..|.|.|.:|:.|  ...|......||:::|::||:...|    ...|.|:.|..|:..:|.||:
Mouse   433 PVYFYEFQHQSSFLKDVRPPHVNADHGDEVPFVFGSFFWG----MKLNLTEEEKLLNRRMMKYWA 493

  Fly   731 NFVRTGNPNEQMETEHGSRQERSRYKTIEWTAYESVHKKYLNFDTKPKLKNHYRAHRLSFWLNLI 795
            ||.|.||||          .|...|    |..::. .::||..:.:|.:....:|.:|.||...:
Mouse   494 NFARHGNPN----------SESLPY----WPVFDH-DEQYLQLNIQPAVGQFQKARKLQFWTKTL 543

  Fly   796 P----------DLHK 800
            |          ::||
Mouse   544 PRKIEELKRSQNVHK 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_731170.2	COesterase	154..791	CDD:395084	179/644 (28%)
Ces2g	NP_932116.2	COesterase	33..539	CDD:395084	179/643 (28%)