Protein Alignment Nlg3 and Ces2f

DIOPT Version :10

• Sequence 1: NP_731170.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_001073334.2
• Gene: Ces2f / 71903
• MGIID: 1919153
• Length: 561
• Species: Mus musculus
• Alignment Length: 657
• Identity: 192/657 - (29%)
• Similarity: 283/657 - (43%)
• Gaps: 147/657 - (22%)

  Fly   149 LPAQLSSRIINTRNGAISGVIVQLDGRHLDPVEA----YRGIPYASPPVGNLRFMPPVSAAMWSG 209
            |.:..:|.|.||..|.:.|..|     ||..::|    :.|||:|.||||.|||.||.:...|||
Mouse    27 LDSSEASPIRNTHTGQVRGKFV-----HLTDIKAGAHNFLGIPFAKPPVGPLRFAPPEAPEPWSG 86

  Fly   210 VKKADRFSPVCPQRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRD 274
            |:.......:|.|. .||.|    ||     .|:.:|.:||.. :.||||||||||.|
Mouse    87 VRDGTSQPAMCLQN-DDIVN----LE-----GLKIIKMILPPF-SMSEDCLYLNIYTP------- 133

  Fly   275 SSGSSSSSSAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSV 339
                                           :.|..||  ..||:|::||........:.|||||
Mouse   134 -------------------------------AHAQEGS--NLPVMVWLHGGGLVAGMASMYDGSV 165

  Fly   340 LASYGQILVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLA 404
            ||:...::||...||||:.||.:...:   :...|:|.:|..|||||:::|||.|||:|:|:||.
Mouse   166 LAATEDVVVVVTQYRLGIPGFYSTGDE---QARGNWGFLDQTAALHWVQQNIANFGGNPDSVTLF 227

  Fly   405 GHGTGAACVHFLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAKYAAIVAHHVNCASDLPHAH 469
            |...|...|.|.:.| .|.:| ||:|||:.||..|.|..:..:|......||:...|.:....|
Mouse   228 GQSAGGTSVSFHVLS-PVSQG-LFHRAIMESGVALLPTIIPDSPEMIFTKVANLSGCETSNSEA- 289

  Fly   470 LMKCLREKTLDQLLSVPIRPPEFGFAFGPSIDGVVIDGGDYVPPAPGSPAAQAQAQASTAAGNGL 534
            |::|||.|:..::|::     ...|.|.|:    |:| |.::|..|....|.|......:. .|:
Mouse   290 LVRCLRGKSEAEILAM-----SKAFRFMPA----VVD-GKFLPRHPKKLLASADFHPVPSI-IGV 343

  Fly   535 GGEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMA--GVTRAEAFFSFNSGDVQYGIEADR 597
            ..:     ..||..|    .|....:| |.|::|.:|.|  .:|..:.......||:
Mouse   344 NND-----EYGWIIP----KIFKFSQT-IRKINRNNLKAIMKITTEQMMLPSECGDL-------- 390

  Fly   598 RSRILKAYVRNTYTFHLNEIFATIVNEYTDWERPVQHPINIRDETLEALSDAQVVAPAAQTVDLH 662
               :::.|:|:|                       :.|..::.:..|.:.|..::.||.| |...
Mouse   391 ---LIEEYLRDT-----------------------EDPWTLQMQFREMIGDFLIIIPALQ-VARF 428

  Fly   663 SADHRNSYLYVFDYQTRFGDY--PQRQGCIHGEDLPYIFGAPLVGGFNHFTRNYTKTEISLSEVV 725
            ...|...|.|.|.:::....|  |......||::|..|||:...|    ...::|..|..||..:
Mouse   429 QRSHAPVYFYEFQHRSSLLKYFRPWHVKADHGDELYLIFGSFFWG----LKFSFTAEEKLLSRKM 489

  Fly   726 MFYWSNFVRTGNPN-EQMETEHGSRQERSRYKTIEWTAYESVHKKYLNFDTKPKLKNHYRAHRLS 789
            |.||:||.|.|||| |.:.....|.|:                ..||..|..|.:.:..:|.||.
Mouse   490 MKYWANFARYGNPNSEDLPYWPASNQD----------------DLYLQLDIHPSVGHALKARRLP 538

  Fly   790 FWLNLIP 796
            ||...:|
Mouse   539 FWTKTLP 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_731170.2	COesterase	154..791	CDD:395084	188/645 (29%)
Ces2f	NP_001073334.2	COesterase	32..540	CDD:395084	188/645 (29%)