Protein Alignment Nlg3 and Ces1a

DIOPT Version :9

• Sequence 1: NP_001036685.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_001177304.1
• Gene: Ces1a / 679817
• RGDID: 1583671
• Length: 563
• Species: Rattus norvegicus
• Alignment Length: 665
• Identity: 180/665 - (27%)
• Similarity: 270/665 - (40%)
• Gaps: 162/665 - (24%)

  Fly   154 SSRIINTRNGAISGVIVQLDGRHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSP 218
            |..:::|..|.:.|..:.|:| ...||..:.|:|:|.||:|:|||.||..|..||.||.|..:.|
  Rat    22 SPPVVDTLQGKVLGKYISLEG-FTQPVAVFLGVPFAKPPLGSLRFAPPQPAESWSFVKNATSYPP 85

  Fly   219 VCPQ------RLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSG 277
            :|.|      .|.::.  |..||.:|   |||           ||||||||||.|..:.|:|
  Rat    86 MCSQITGVGPVLSEVF--TNQLENVP---LEY-----------SEDCLYLNIYSPTDLTSKD--- 131

  Fly   278 SSSSSSAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLAS 342
                                                 :.||:|:|||........:.:||..|::
  Rat   132 -------------------------------------RLPVMVWVHGGGLLSGGASTFDGLALST 159

  Fly   343 YGQILVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHG 407
            :.:::||.|.||||:.|||:.. |.:|:  .|:|..|.:|||.|::.||..|||||||:||.|..
  Rat   160 HEKVVVVVIQYRLGIWGFLSTG-DEHSR--GNWGHFDQVAALQWVQNNIVNFGGDPNSVTLFGES 221

  Fly   408 TGAACVHFLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAKYAAIVAHHVNCASDLPHAHLMK 472
            .|...|..|:.|.....  ||:|||..||..|.|.....|....|..||....||: ...|.:::
  Rat   222 AGGESVSVLVLSPLTKN--LFHRAISESGVALTPCLFRENTRLAAEQVAIATGCAA-TTSADIVR 283

  Fly   473 CLREKTLDQLLSVPIR----------PPEFGFAFGPS-IDGVVIDGGDYVPPAPGSPAAQAQAQA 526
            ||||||.::||:..::          .|...:.|..: ||||::      |.||       :...
  Rat   284 CLREKTEEELLATTLKMKFFALDLHGDPRESYPFLTTVIDGVLL------PKAP-------EEIL 335

  Fly   527 STAAGNGLGGEAGI-AAAGGWGTPGQ----LENIVLMRKTAINKLSRYDLMAGVTRAEAFFSFNS 586
            |....|.:....|| ....||..|..    |....|.:|||.:.|.:...:..:::
  Rat   336 SEKNFNTVPYIVGINKQEFGWFIPTMMGYPLSESKLDQKTATSLLWKSYPLTNISK--------- 391

  Fly   587 GDVQYGIEADRRSRILKAYVRNTYTFHLNEIFATIVNEYTDWERPVQHPINIRDETLEALSDAQV 651
                                         |:......:|....   ..|...:|..|:.:.|...
  Rat   392 -----------------------------ELTPVATEKYLGGS---DCPDKKKDLFLDMMGDVLF 424

  Fly   652 VAPAAQTVDLHSADHRNSYLYVFDYQTRF-GDY-PQRQGCIHGEDLPYIFGAPLVGGFNHFTRNY 714
            ..|:......|......:|:|.|.|...| .|. |:.....||:::..::|.|.:      ....
  Rat   425 AVPSVIVARYHRDARATTYVYEFKYHPSFVSDMRPKTVIADHGDEVYSVWGTPFL------KEGA 483

  Fly   715 TKTEISLSEVVMFYWSNFVRTGNPNEQMETEHGSRQERSRYKTIEWTAYESVHKKYLNFDTKPKL 779
            ::.||:||.::|.:|.||.|.||||.: ...|             |..|:. .:.||...|..:.
  Rat   484 SEEEINLSTMMMKFWGNFARNGNPNGE-GLPH-------------WPEYDE-KESYLQIGTTIQQ 533

  Fly   780 KNHYRAHRLSFWLNL 794
            ....:...::||..|
  Rat   534 AQKLKYKEVAFWTGL 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_001036685.2	COesterase	151..791	CDD:278561	177/660 (27%)
		Aes	<313..>410	CDD:223730	40/96 (42%)
Ces1a	NP_001177304.1	COesterase	24..545	CDD:278561	176/658 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336079
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740