Protein Alignment Nlg3 and Ces5a

DIOPT Version :10

• Sequence 1: NP_731170.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_001368779.1
• Gene: Ces5a / 67935
• MGIID: 1915185
• Length: 579
• Species: Mus musculus
• Alignment Length: 679
• Identity: 180/679 - (26%)
• Similarity: 260/679 - (38%)
• Gaps: 211/679 - (31%)

  Fly   160 TRNGAISGVIVQLDGRHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSPVCPQRL 224
            |:.|.:.|....:.|| |:||..:.|||:|:||:|.|||..|.....|..:::|..:..:|.|
Mouse    39 TKLGWVQGKQATVLGR-LEPVNVFLGIPFAAPPLGPLRFSKPQPPIPWDNLREATAYPNLCFQ-- 100

  Fly   225 PDIHNETAALERMPKGRLEYL---KRLL----PYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSSS 282
                            .||:|   :.||    |.| ..||||||||||.|...    ::|||
Mouse   101 ----------------NLEWLFIYQNLLKVSYPIL-GMSEDCLYLNIYAPCHA----NNGSS--- 141

  Fly   283 SAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASYGQIL 347
                                             .||:|::.|..:|..|.:.:|||.||.|..:|
Mouse   142 ---------------------------------LPVMVWIPGGGFETGSASIFDGSALAVYEDVL 173

  Fly   348 VVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAAC 412
            ||||.||||:.||.   |.:....|.|:...|.:|||.|::|||..|||:|:|:|:.|:..||..
Mouse   174 VVTIQYRLGIFGFF---TTQNQHAPGNWAFWDQLAALLWVRENIKYFGGNPDSVTIFGNSAGAIS 235

  Fly   413 VHFLISSMAVPEGLLFNRAILMSGSGLAPWSLVS--NPAKY-AAIVAHHVNC-ASDLPHAHLMKC 473
            :..||.|....:  ||:|||:.||..:.| ||.|  |..|: ..:||:..:| .||  ...|:||
Mouse   236 ISSLILSPLSAD--LFHRAIMQSGVAIIP-SLKSSDNDLKHDLQVVANVCDCNVSD--SKALLKC 295

  Fly   474 LREKTLDQLLSVPIRPPEF-----GFAFG---------------PSIDGVVIDGGDYVPPAPGSP 518
            ||||:..:|:|:..:...|     |..|.               |||.||......|:.|...:|
Mouse   296 LREKSSLELMSLSQKAKSFTRVVDGSFFSEEPLELLSQKTLKIVPSIIGVNNQECGYILPVRDTP 360

  Fly   519 AAQAQAQASTAAGNGLGGEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAFFS 583
            .....:..|||.                              |.|:.|..
Mouse   361 EILLGSNESTAL------------------------------TLIHTLLH--------------- 380

  Fly   584 FNSGDVQYGIEADRRSRILKAYVRNTYTFHLNEIFATIVNEYTDWERPVQHPINIRDETLEALSD 648
                     |.......:.|.|....::                       |.:|||..|:...|
Mouse   381 ---------IPTQHLYIVTKEYFHGKHS-----------------------PTDIRDTLLDLFGD 413

  Fly   649 AQVVAPAAQTVDLHSADHRNSYLYVFDYQTRFGDYPQRQGCI-----------HGEDLPYIFGAP 702
            ...|.|...|...|.......|.|.|.:         |..|.           |.:::.::||.|
Mouse   414 VFFVVPGLVTARYHRDSGGPVYFYEFQH---------RPHCFQNSRPAFVKADHTDEIRFVFGGP 469

  Fly   703 LVGGFNHFTRNYTKTEISLSEVVMFYWSNFVRTGNPNEQMETEHGSRQERSRYKTIEWTAYESVH 767
            .:.|........|:.|..||..:|.||:||.|:|:||       |:       ....|..|:. :
Mouse   470 FLKGDVVMFEEATEEEKLLSRKMMKYWANFARSGDPN-------GA-------DLPPWPVYDE-N 519

  Fly   768 KKYLNFDTKPKLKNHYRAHRLSFWLNLIP 796
            ::||..|.........:..|:.||.:.:|
Mouse   520 EQYLELDVNISTGRRLKDQRVEFWTDTLP 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_731170.2	COesterase	154..791	CDD:395084	177/672 (26%)
Ces5a	NP_001368779.1	COesterase	33..543	CDD:395084	177/672 (26%)