DRSC/TRiP Functional Genomics Resources

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Protein Alignment Nlg3 and LOC679149

DIOPT Version :9

Sequence 1:NP_001036685.2 Gene:Nlg3 / 40912 FlyBaseID:FBgn0083963 Length:1159 Species:Drosophila melanogaster
Sequence 2:NP_001094469.1 Gene:LOC679149 / 679149 RGDID:1591847 Length:561 Species:Rattus norvegicus


Alignment Length:672 Identity:186/672 - (27%)
Similarity:276/672 - (41%) Gaps:187/672 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   154 SSRIINTRNGAISGVIVQLDGRHLDPVEA----YRGIPYASPPVGNLRFMPPVSAAMWSGVKKAD 214
            ||.|.||..|.:.|   :||  |:...:|    :.|||:|.||||.|||.||.:...||||:...
  Rat    32 SSPIRNTHIGQVRG---KLD--HVKDTKAGVHTFLGIPFAKPPVGPLRFAPPEAPEPWSGVRDGT 91

  Fly   215 RFSPVCPQRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSS 279
            ....:|.|.|..|:.|          .|:.:|..||.: :.||||||||||.|            
  Rat    92 SQPAMCLQNLDVINAE----------GLKEMKLKLPPV-SMSEDCLYLNIYAP------------ 133

  Fly   280 SSSSAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASYG 344
                                      :.|..||  ..||:|::||........:.||||:|....
  Rat   134 --------------------------AHAHEGS--NLPVMVWIHGGGLMTGMASMYDGSLLTVNE 170

  Fly   345 QILVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTG 409
            .::||||.||||||||.:.. |.:::  .|:|.:|.:|||.|:::|||.|||:|:.:|:.|...|
  Rat   171 DLVVVTIQYRLGVLGFFSTG-DEHAR--GNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAG 232

  Fly   410 AACVH-FLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAKYAAIVAHHVNCASDLPHAHLMKC 473
            ..||. .::|.|:  :| ||:.||:.||..|.|:.:......::.:||....|.: :....|:.|
  Rat   233 GTCVSTHVVSPMS--QG-LFHGAIMESGVALLPYLIADTSEMFSTMVAKVSGCEA-MDSEALVHC 293

  Fly   474 LREKTLDQLLSV----------------PIRPPEF----GFAFGPSIDGVVIDGGDYVPPAPGSP 518
            ||.|:..::|::                |..|.|.    .|...|||.||  :..:|        
  Rat   294 LRAKSEAEILAINKVVQMVPAVVDGEFLPRHPKELLASEDFRPVPSIIGV--NNDEY-------- 348

  Fly   519 AAQAQAQASTAAGNGLGGEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGV--TRAEAF 581
                                      ||..|     :|:.....|.:|||.:|.|.:  |.|:..
  Rat   349 --------------------------GWTIP-----LVMGTTQMIKELSRENLQAILKKTTAQLM 382

  Fly   582 FSFNSGDVQYGIEADRRSRILKAYVRNTYTFHLNEIFATIVNEYTDWERPVQHPINIRDETLEAL 646
            ......|:                               ::.||..   .::.|..::.:..|.:
  Rat   383 LPLECSDL-------------------------------LMEEYMG---DIEDPKTLQAQFTELM 413

  Fly   647 SDAQVVAPAAQTVDLHSADHRNSYLYVFDYQTRF--GDYPQRQGCIHGEDLPYIFGAPLVGGFNH 709
            .|...|.||.|.... ...|...|.|.|.:|..|  ...|......||:::|::||.    .|..
  Rat   414 EDFMFVIPALQVAHF-QCSHAPVYFYEFQHQITFLKDIRPPHVKADHGDEIPFVFGY----FFWD 473

  Fly   710 FTRNYTKTEISLSEVVMFYWSNFVRTGNPNEQMETEHGSRQERSRYKTIEWTAYESVHKKYLNFD 774
            ...::|:.|..||..:|.||:||.|.||||          .|...|    |...:. .::||..|
  Rat   474 MKTDFTEEEKLLSRRMMKYWANFARHGNPN----------SEGLSY----WPVMDH-DQQYLQLD 523

  Fly   775 TKPKLKNHYRAHRLSFWLNLIP 796
            |:|.:....:|.||.||...:|
  Rat   524 TQPAVGRALKARRLQFWTKTLP 545

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Nlg3NP_001036685.2 COesterase 151..791 CDD:278561 183/665 (28%)
Aes <313..>410 CDD:223730 39/96 (41%)
LOC679149NP_001094469.1 COesterase 31..540 CDD:278561 183/665 (28%)
Aes <130..>233 CDD:223730 45/145 (31%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166336075
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1516
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
43.740

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