Protein Alignment Nlg3 and ces3

DIOPT Version :10

• Sequence 1: NP_731170.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_001038401.1
• Gene: ces3 / 560651
• ZFINID: ZDB-GENE-030131-9563
• Length: 549
• Species: Danio rerio
• Alignment Length: 657
• Identity: 173/657 - (26%)
• Similarity: 271/657 - (41%)
• Gaps: 155/657 - (23%)

  Fly   154 SSRIINTRNGAISGVIVQLDGRHLDP--VEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRF 216
            |..::..::|::.|..|:..|   .|  ||.|.|||:|.||||..|...|.....|.|::.|..:
Zfish    25 SGPVVVLKHGSVRGQYVKAKG---SPAVVEQYLGIPFAQPPVGPHRLAAPQPVQGWEGIRNATEY 86

  Fly   217 SPVCPQRLPDI---HNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGS 278
            |.:|.|. |:|   :.::..||..|.|              .||||||||:|.|.|....|
Zfish    87 SSMCLQD-PNIVPKYAKSMTLELPPTG--------------VSEDCLYLNVYTPSQRSESD---- 132

  Fly   279 SSSSSAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASY 343
                                                |:||:|::||.:........|||:.||:|
Zfish   133 ------------------------------------KFPVMVWIHGGALVIGGACMYDGTPLAAY 161

  Fly   344 GQILVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGT 408
            .:::||.|.||||:||:|:.. |::::  .|:|.:|.||||.|:::||.||||||.|:|:||...
Zfish   162 EKVVVVVIQYRLGILGYLSTG-DQHAQ--GNWGFLDQIAALQWVQQNIEAFGGDPQSVTIAGESA 223

  Fly   409 GAACVHFLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAKYAAIVAHHVNC---ASDLPHAHL 470
            |......|..| .:.:| ||.|||..||..........:|..||.::|:...|   :|::    |
Zfish   224 GGISASLLTLS-PMTKG-LFQRAIFQSGVATVKGYSFKDPLTYAKVIANITECDFSSSEV----L 282

  Fly   471 MKCLREKTLDQLLSVPIRPPEFGFAFGPSIDGVVIDGGDYVPPAPGSPAAQAQAQASTAAGNGLG 535
            :||:||.|.:|::....:...        :.|..:| |:::...|
Zfish   283 VKCIREMTEEQIIKAAQKKYR--------LPGATVD-GEFIKAQP-------------------- 318

  Fly   536 GEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAFFSFNSG----DVQYGIEAD 596
                             |.|:..:     ...:..::.|.|..|..::.:..    |...|::|.
Zfish   319 -----------------EEILKSK-----DFPKIPILVGTTNHEFGWTLSHAILPKDWAKGMDAK 361

  Fly   597 RRSRILKAYVRNTYTFHLNEIFATIVNEYTDWERPVQHPINIRDETLEALSDAQVVAPAAQTVDL 661
            ...:.|..:    |....:|....|.:||.   :..:.|..|||...|.|.|..:|.|:.:....
Zfish   362 SAKQTLDFF----YNAGASEANGIIADEYF---KNAKTPEEIRDAFTELLGDIIMVIPSIKVASY 419

  Fly   662 HSADHRNSYLYVFDYQTRFGD--YPQRQGCIHGEDLPYIFGAPLVGGFNHFTRNYTKTEISLSEV 724
            |.......|:|.|.:.....:  .|......||:::.::|||....|....|...|:.|..|...
Zfish   420 HRDAGAPVYMYEFQHGPSIANKFRPSFVKADHGDEIGFMFGACFWDGQVKVTGTLTEEENQLCRT 484

  Fly   725 VMFYWSNFVRTGNPNEQMETEHGSRQERSRYKTIEWTAYESVHKKYLNFDTKPKLKNHYRAHRLS 789
            ||.||:||||||:||.               ..:.|..|:. ..||||...:.......:..:|.
Zfish   485 VMKYWANFVRTGSPNP---------------APVPWPVYDQ-SNKYLNLGLQQTEGQGLKKDKLL 533

  Fly   790 FWLNLIP 796
            |:...:|
Zfish   534 FFTEELP 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_731170.2	COesterase	154..791	CDD:395084	171/650 (26%)
ces3	NP_001038401.1	COesterase	25..535	CDD:395084	171/650 (26%)